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NVP-LAQ824

Name: NVP-LAQ824
Brand: Cuicheng Bio
SKU: pr2606011629
Price: 12000 USD
Availability: InStock

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CAS No.:

404951-53-7

Grade:

Industrial Grade

Content:

98%

Port:

guanghzou

Brand:

Cuicheng Bio

Packaging:

g/kg

Price valid (until):

2026-07-02

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
Seller Information

Description

NVP-LAQ824 (also known as Dacinostat; CAS No.: 404951-53-7) functions primarily as a potent, novel, broad-spectrum Histone Deacetylase (HDAC) inhibitor [404951-53-7]. It exerts significant anticancer activities at nanomolar concentrations, with an in vitro inhibitory concentration ($\text{IC}_{50}$) ranging between 30 to 32 nM. As a hydroxamic acid derivative, it is extensively investigated in biomedical research as a targeted anti-tumor agent.

The essential function of NVP-LAQ824 (Dacinostat) is to serve as a nanomolar pan-HDAC inhibitor that remodels the epigenetic landscape. By boosting histone acetylation, upregulating the p21 suppressor pathway, disrupting the Hsp90 chaperone system, and cutting off VEGF-driven angiogenesis, it selectively drives cell cycle arrest and apoptosis across a broad spectrum of drug-resistant hematological and solid tumors.

Items	Specifications

Basic Info

Product Name:

Dacinostat

Other Name:

2-Propenamide,N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-,(2E)-;(2E)-N-Hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide;Dacinostat;NVP-LAQ 824

CAS No.:

404951-53-7

Molecular Formula:

C22H25N3O3

InChIKeys:

InChIKey=BWDQBBCUWLSASG-MDZDMXLPSA-N

Molecular Weight:

379.4522

Exact Mass:

379.45

Categories:

Organic Reagents

Characteristics

PSA:

88.59000

XLogP3:

3.41

Density:

1.3±0.1 g/cm3

Refractive Index:

1.693

See More Dacinostat Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Dacinostat Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

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Product Name	Grade / Content	Price	Supplier Name	Details
2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)- 99% white powder kanbei	Industrial Grade/99		Henan Lihao Chem Plant Limited	Inquiry