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Dietary Supplement Ingredient Nutrition Enhancement CAS 34717-03-8 Magnesium Orotate

Name: Dietary Supplement Ingredient Nutrition Enhancement CAS 34717-03-8 Magnesium Orotate
Brand: ONERBIO
SKU: pr2606021211
Price: 10.7 USD
Availability: InStock

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Unit Price:

$10.7/KG FOB

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CAS No.:

34717-03-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

ONERBIO

Packaging:

25kg/drum

Price valid (until):

2026-12-31

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Wuhan Oner Biotech Co.,Ltd.

Company Type:

Distributor

Location:

China

Qualification:

Main Products:

Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

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Product Description
Seller Information
Inquiry History

Description

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Product Name: Magnesium Orotate
CAS Number: 27067-92-1
Molecular Formula: C₁₀H₆MgN₄O₈
Molecular Weight: 334.48 g/mol
Appearance: White to off-white crystalline powder

Magnesium orotate is a magnesium salt of orotic acid, a pyrimidine carboxylic acid involved in pyrimidine biosynthesis. It appears as a white to off-white crystalline powder, essentially odorless, with poor solubility in water and common nonpolar media, while showing limited solubility in some aqueous systems under specific pH conditions. The compound contains one magnesium ion associated with two orotate anions, giving a defined stoichiometric composition. It is stable under ordinary storage conditions when kept dry and protected from excessive heat, light, and strong oxidizing agents. Functionally, magnesium orotate is used as a mineral supplement and as a source of both magnesium and orotate. It is studied for supporting energy-related processes, cardiovascular function, and muscular performance. In pharmaceutical and nutraceutical formulations, it may be incorporated into tablets, capsules, and powders. In biochemical research, it serves as a tool for examining pyrimidine metabolism and mineral transport. It should be stored in a tightly closed container in a cool, dry place. Standard laboratory handling practices are recommended, including eye protection, gloves, and adequate ventilation. This material is generally regarded as low toxicity, but contact with eyes, skin, and respiratory tract should be minimized. Avoid incompatible oxidizers.

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ITEMS	STANDARDS		RESULTS
Description	White to almost white powder		White powder
UV absorbance ratio	A250/A260 A280/A260	0.41-0.49 2.03-2.71	0.45 2.14
PH	2.0-4.0		2.68
Loss on drying	≤5.0%		2.64%
Assay (UV)	≥98.0%		99.17%
Transmittance	≥98.5%		99.1%
Heavy metals	≤10ppm		＜10ppm
Purity (HPLC)	≥98.0%		99.6%
Conclusion	It complies to the standard

For regulatory compliance (e.g., USP, EP, JP), raw material Vidarabine must meet several rigorous standards:

Assay (by HPLC): 98.0% – 102.0% on an anhydrous basis.
Related Substances: Limits for specific impurities, notably Ara-Hx (NMT 2.0%), as well as any unspecified individual impurity (NMT 0.1%) and total impurities (NMT 2.0%).
Residual Solvents: Must comply with ICH Q3C guidelines (Class 1 and 2 solvents limited or absent).
Heavy Metals: NMT 20 ppm (typically lower for injectable grades).
Water Content (Karl Fischer): NMT 6.0% (the material is hygroscopic to a degree).
Microbial Limits: Total aerobic microbial count (TAMC) ≤ 1000 CFU/g, absence of S. aureus, P. aeruginosa, and Candida albicans.

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As a high-purity pharmaceutical intermediate, L-Tyrosine Ethyl Ester Hydrochloride is predominantly utilized in the chemical synthesis of bioactive peptides, dopamine analogs, and melanin precursors. Its excellent solubility profile makes it an ideal chiral building block for asymmetric synthesis and a critical substrate in enzymatic reactions. Available in purity grades of ≥98% (HPLC), it meets stringent requirements for R&D and cGMP manufacturing processes. Reliable supply ensures batch-to-batch consistency for long-term project scalability.

Vidarabine is classified as a potential reproductive hazard and an irritant. Safety Data Sheets (SDS) mandate the following:

Hazard Statements (H360): May damage fertility or the unborn child (Category 1B).
Precautionary Measures: Use fume hoods and wear impermeable gloves (e.g., nitrile), lab coats, and safety goggles. Avoid generating airborne dust.
First Aid: In case of skin contact, wash immediately with copious soap and water. If inhaled, move to fresh air.
Storage: Store in tightly sealed, light-resistant containers at 2°C to 8°C (refrigerated) for long-term stability. Avoid freezing.

While superseded by newer nucleoside analogs (Acyclovir, Ganciclovir) for systemic use due to better bioavailability and lower toxicity, Vidarabine retains niche value. Its primary current application is ophthalmic ointment (3%) . Pharmacokinetically, the raw material has poor oral bioavailability (<10%) and is rapidly deaminated in the gastrointestinal tract, necessitating parenteral or topical administration.

Vidarabine API is a well-characterized, stable crystalline nucleoside analog. While its systemic use has declined, it remains a critical raw material for topical antiviral ophthalmic preparations, particularly where resistance to other agents occurs. Manufacturers must strictly control impurities (especially Ara-Hx) and water content to ensure final drug product efficacy.

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ECHEMI Editorial Reference

Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat Mg deficiency. Orotic acid acts as a transporter that carries magnesium into the cells. It also exhibits antioxidant properties, since it is a key intermediate in the biosynthetic pathway of pyrimidines that promotes the synthesis of enzymes which act as free radical scavengers. Experiments investigating the potential cardioprotective actions of orotic acid in pathological heart conditions are still ongoing.

Certificates

Basic Info

Product Name:

Magnesium orotate

Other Name:

Magnesium,bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-κN3,κO4)-,(T-4)-;Magnesium,bis(orotato)-;Magnesium,bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-N3,O4)-,(T-4)-;4-Pyrimidinecarboxylic acid,1,2,3,6-tetrahydro-2,6-dioxo-,magnesium complex;(T-4)-Bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-κN3,κO4)magnesium;Magnesium orotate;Magnerot;11097-30-6;27067-77-2

CAS No.:

34717-03-8

Molecular Formula:

C10H6MgN4O8

InChIKeys:

InChIKey=QWLHYYKDLOVBNV-UHFFFAOYSA-L

Molecular Weight:

334.48200

Exact Mass:

334.00400

EC Number:

252-167-6

UNII:

GI96W46M5A

ATC Code:

A - Alimentary tract and metabolism

Categories:

Nutrition Supplements

Characteristics

PSA:

184.04000

XLogP3:

-2.63140

Appearance:

A white to almost white crystalline powder.

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Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Magnesium orotate Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

Location:
Changqing 5th Road, Jianghan District

Payment Terms:
TT against copy of documents

Average lead Time:
5

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
5-10

Year of Establishment:
2020

Wuhan Oner Biotech Co.,Ltd. located in the popular city of Wuhan, specilize in producing and developing pharmaceutical & its intermediates, Cosmetics Raw Material and Intermediate, food additive, Plant extracts,and in distributing the products of our own company. We serves our clients by supplying high-quality.These products are manufactured in ISO 9001 certified plants and have continuously been passing quality inspection by CIQ (China Entry & Exit Inspection and Quarantine Bureau),100% pass rate. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , the products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

Inquiry History

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Country	Product	Purchase Quantity	Date Posted
Canada	Magnesium orotate	1000 G	May 26, 2026

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