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Natural Premium Ginseng Root Extract 15% Ginsenoside Rh2 From China

Name: Natural Premium Ginseng Root Extract 15% Ginsenoside Rh2 From China
Brand: ONERBIO
SKU: pr2606021219
Price: 10.19 USD
Availability: InStock

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Unit Price:

$10.19/KG FOB

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CAS No.:

78214-33-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

ONERBIO

Packaging:

25kg/drum

Price valid (until):

2026-12-31

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Wuhan Oner Biotech Co.,Ltd.

Company Type:

Distributor

Location:

China

Qualification:

Main Products:

Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

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Product Description
Seller Information

Description

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Product Name: Ginsenoside Rh2
CAS Number: 78214-33-2
Molecular Formula: C₃₆H₆₂O₈
Molecular Weight: 622.87 g/mol
Appearance: White to off-white crystalline powder

Ginsenoside Rh2 is a naturally occurring dammarane-type triterpenoid saponin and a minor ginsenoside found in Panax species, especially after processing. It appears as a white to off-white crystalline powder. The compound is poorly soluble in water but dissolves in certain polar and medium-polar organic liquids. Its structure contains a tetracyclic dammarane skeleton with attached sugar and hydroxyl groups, giving it amphiphilic character and enabling interactions with biological membranes and proteins. Ginsenoside Rh2 belongs to the protopanaxadiol subgroup and differs from related ginsenosides by its sugar linkage pattern and stereochemistry. The 20(S) form is commonly referenced, while the 20(R) epimer also exists. Functionally, Ginsenoside Rh2 is widely studied for antiproliferative, pro-apoptotic, anti-inflammatory, antioxidant, and immunomodulatory activities. It is used in cancer research, cell signaling investigations, and studies of cell cycle progression, apoptosis, and angiogenesis. It may also influence metabolic regulation and neuroprotective pathways. Laboratory studies suggest it can modulate multiple signaling cascades linked to oxidative stress, inflammation, and programmed cell death. In nutraceutical and cosmetic development, it is explored for skin care, anti-aging, and wellness applications. It serves as an analytical standard and a synthetic target in saponin chemistry. Because of low water solubility, formulations often require suitable delivery systems to improve dispersion and bioavailability. Store in a cool, dry, dark place, protected from heat, moisture, and strong oxidizing agents. Handle with standard laboratory precautions.

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ITEMS	STANDARDS		RESULTS
Description	White to almost white powder		White powder
UV absorbance ratio	A250/A260 A280/A260	0.41-0.49 2.03-2.71	0.45 2.14
PH	2.0-4.0		2.68
Loss on drying	≤5.0%		2.64%
Assay (UV)	≥98.0%		99.17%
Transmittance	≥98.5%		99.1%
Heavy metals	≤10ppm		＜10ppm
Purity (HPLC)	≥98.0%		99.6%
Conclusion	It complies to the standard

For regulatory compliance (e.g., USP, EP, JP), raw material Vidarabine must meet several rigorous standards:

Assay (by HPLC): 98.0% – 102.0% on an anhydrous basis.
Related Substances: Limits for specific impurities, notably Ara-Hx (NMT 2.0%), as well as any unspecified individual impurity (NMT 0.1%) and total impurities (NMT 2.0%).
Residual Solvents: Must comply with ICH Q3C guidelines (Class 1 and 2 solvents limited or absent).
Heavy Metals: NMT 20 ppm (typically lower for injectable grades).
Water Content (Karl Fischer): NMT 6.0% (the material is hygroscopic to a degree).
Microbial Limits: Total aerobic microbial count (TAMC) ≤ 1000 CFU/g, absence of S. aureus, P. aeruginosa, and Candida albicans.

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As a high-purity pharmaceutical intermediate, L-Tyrosine Ethyl Ester Hydrochloride is predominantly utilized in the chemical synthesis of bioactive peptides, dopamine analogs, and melanin precursors. Its excellent solubility profile makes it an ideal chiral building block for asymmetric synthesis and a critical substrate in enzymatic reactions. Available in purity grades of ≥98% (HPLC), it meets stringent requirements for R&D and cGMP manufacturing processes. Reliable supply ensures batch-to-batch consistency for long-term project scalability.

Vidarabine is classified as a potential reproductive hazard and an irritant. Safety Data Sheets (SDS) mandate the following:

Hazard Statements (H360): May damage fertility or the unborn child (Category 1B).
Precautionary Measures: Use fume hoods and wear impermeable gloves (e.g., nitrile), lab coats, and safety goggles. Avoid generating airborne dust.
First Aid: In case of skin contact, wash immediately with copious soap and water. If inhaled, move to fresh air.
Storage: Store in tightly sealed, light-resistant containers at 2°C to 8°C (refrigerated) for long-term stability. Avoid freezing.

While superseded by newer nucleoside analogs (Acyclovir, Ganciclovir) for systemic use due to better bioavailability and lower toxicity, Vidarabine retains niche value. Its primary current application is ophthalmic ointment (3%) . Pharmacokinetically, the raw material has poor oral bioavailability (<10%) and is rapidly deaminated in the gastrointestinal tract, necessitating parenteral or topical administration.

Vidarabine API is a well-characterized, stable crystalline nucleoside analog. While its systemic use has declined, it remains a critical raw material for topical antiviral ophthalmic preparations, particularly where resistance to other agents occurs. Manufacturers must strictly control impurities (especially Ara-Hx) and water content to ensure final drug product efficacy.

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ECHEMI Editorial Reference

Ginsenoside Rh2 is isolated from the root of Ginseng. Ginsenoside Rh2 induces the activation of caspase-8 and caspase-9. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-path manner.
(20S)-ginsenoside Rh2 is a ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, an antineoplastic agent, an apoptosis inducer, a cardioprotective agent, a bone density conservation agent and a hepatoprotective agent. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a ginsenoside, a tetracyclic triterpenoid and a 20-hydroxy steroid. It derives from a hydride of a dammarane.

Certificates

Basic Info

Product Name:

Ginsenoside Rh2

Other Name:

β-D-Glucopyranoside,(3β,12β)-12,20-dihydroxydammar-24-en-3-yl;Dammarane,β-D-glucopyranoside deriv.;(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl β-D-glucopyranoside;Ginsenoside Rh2;3-O-β-D-Glucopyranosyl-20(S)-protopanaxadiol;20(S)-Ginsenoside Rh2;20(S)-Rh2;Ginsenoside 20-Rh2;Ginsenoside rh2(S);67400-18-4

CAS No.:

78214-33-2

Molecular Formula:

C36H62O8

InChIKeys:

InChIKey=CKUVNOCSBYYHIS-IRFFNABBSA-N

Molecular Weight:

622.87

Exact Mass:

622.87

UNII:

0JU44A5KWG

DSSTox ID:

DTXSID60855750

HScode:

29389090

Categories:

Nutrition Supplements

Characteristics

PSA:

140

XLogP3:

5.6

Appearance:

White powder

Density:

1.2±0.1 g/cm3

Melting Point:

139-144 °C

Boiling Point:

726.4ºC at 760 mmHg

Flash Point:

393.1±32.9 °C

Refractive Index:

1.572

Storage Conditions:

2-8°C

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Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Ginsenoside Rh2 Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

Location:
Changqing 5th Road, Jianghan District

Payment Terms:
TT against copy of documents

Average lead Time:
5

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
5-10

Year of Establishment:
2020

Wuhan Oner Biotech Co.,Ltd. located in the popular city of Wuhan, specilize in producing and developing pharmaceutical & its intermediates, Cosmetics Raw Material and Intermediate, food additive, Plant extracts,and in distributing the products of our own company. We serves our clients by supplying high-quality.These products are manufactured in ISO 9001 certified plants and have continuously been passing quality inspection by CIQ (China Entry & Exit Inspection and Quarantine Bureau),100% pass rate. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , the products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.
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