KissPeptin-10 is of high quality and purity, and is sold directly by the manufacturer.

Description

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Kisspeptin-10, also called Metastin (45-54), is a 10 amino acid peptide that corresponds to the bioactive C-terminal 45-54 amino acids of metastin, a metastasis suppressor gene product. It acts as a potent agonist of GPR54 (OT7T175, AXOR12), with approximately 8-fold higher binding affinity than metastin (Ki values of 0.042 and 0.34 nM, respectively, for displacement of metastin (40-54)). Metastin (45-54) induces calcium mobilization in GPR54-transfected cells (EC50 = 0.18-1.1 nM). It inhibits the migration of GPR54-transfected CHO cells at concentrations of 10-100 nM, equaling thepotency of full length metastin.

Applications and Effects:

① Reproductive Regulation: Kisspeptin-10 plays a crucial role in reproductive biology and is a key regulator of the hypothalamic-pituitary-gonadal axis. It primarily regulates gonadal function and the reproductive cycle by binding to the kissin receptor GPR54 (also known as KISS1), influencing the secretion of gonadotropin-releasing hormone (GnRH). In rodent models, kisspeptin-10 plays a crucial role in the onset of puberty and the maintenance of reproductive function.

② Vasoconstriction and Angiogenesis: Kisspeptin-10 not only plays a role in the reproductive system but also has potential effects on the cardiovascular system. Studies have shown that kisspeptin-10 can increase cardiac contractility and induce fibrosis and changes in mitochondrial structure in rat heart tissue. These changes suggest that kisspeptin-10 may play a key role in the pathogenesis of heart disease.

③ Antioxidant Activity: Studies have shown that kisspeptin-10 also has potential antioxidant activity, potentially reducing the reproductive toxicity induced by certain drugs, such as methotrexate, this makes kisspeptin-10 a potential therapeutic peptide that can be used to improve sexual desire, muscle growth, and other aspects.

Function

1. 1.Treatment of depression and anxiety disorders: Retatrutide has been shown to have antidepressant and anxiolytic effects in preclinical studies, suggesting that it could be a promising treatment option for individuals with these conditions.
2. 2.Prevention of neurodegenerative diseases: Retatrutide has neuroprotective properties that may be useful in preventing or slowing the progression of neurodegenerative diseases such as Alzheimer's and Parkinson's.
3. 3.Enhancement of cognitive function: Retatrutide has been shown to improve learning and memory in animal studies, suggesting that it could have potential as a cognitive enhancer in humans.
4. 4.Treatment of chronic pain: Retatrutide has been shown to have analgesic effects in preclinical studies, suggesting that it could be a useful treatment option for individuals with chronic pain conditions.
5. 5.Promotion of wound healing: Retatrutide has been shown to accelerate wound healing in animal studies, suggesting that it could have potential as a therapeutic agent for promoting wound healing in humans.
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Superiority

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address

1.High quality and competitive price.
2.Free sample for your evaluation.
3.Promptly delivery by well-reputed shipping lines.
4.Trial order is available for testing after samples.
5.We will inform you all the information at every stage in advance.
6.Packaging can gear to buyers' special request. 

Our service

1. Reply your inquiry in 24 working hours.
2. Customized design is available. OEM are welcomed.
3. Exclusive and unique solution can be provided to our customer by our well-trained and professional engineers and
staff.
4. Professional factory: We are manufacturer, specializing in producing all kinds of herb extract for more than 10 years, competitive with good quantity.
5. As an honest seller, we always use superior raw material, advanced machines, skilled technicians to ensure our products to be finished in high quality and stable feature.

FAQ

Q1:Are you a supplier or a manufacturer?

A:We are both a supplier and a manufacturer.

Q2:How will you deliver the goods?

A:We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.

Q3:Which kind of payment terms do you accept?

A:, Bitcoin, PayPal.USDT.

Q4:How is the after-sales service?

A:We will provide high-quality products and ensure 100% safe deliver.

Q5:how can we guarantee quality?

A:We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality.

Q6: How to confirm the Product Quality before placing orders?

A:You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q7:Is there any discount?

A:Yes, for larger quantity, we always support with better pric e

Company Introduction

Shanxi An Da Si Hai Technology Co., Ltd. is a professional manufacturer of various peptide products and chemical raw materials.

We have a dedicated R&D team and a reliable, efficient logistics team to ensure you receive high-quality products safely and promptly.In order to serve customers well, the company has established special technical department and after-sale service department. Our customers come from countries including the United States, Europe,

Europe, Japan, South Korea, and India. Most of our main products are in stock and ready for immediate shipment.  Please let us know the specific quantity you need.

We will make careful reply if you get any question. We will satisfy market demands by top products and better service, and will welcome market challenge .We will offer you the most competitive price. Feel free to contact us for more information.