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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Retatrutide for Sale > Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic
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Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic buy - image1
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Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic buy - image4
Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic buy - image5
Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic buy - image6

Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic

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Unit Price:

$30/UNIT FOB

Get Latest Price
CAS No.:

2381089-83-2

Grade:

Cosmetics Grade

Content:

99%

Port:

Chinese mainland

Brand:

Any

Packaging:

5mg*10vials 10mg*10vials 15mg*10vials 20mg*10vials 30mg*10vials 40mg*10vials 50mg*10vials 60mg*10vials

Sample Available:

Yes

Price valid (until):

2026-10-29

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
45 days
Qualification:
Main Products:

Semag lutide,Tirzepatide,Retatrutide,raw material,GHK-CU,TB500(Thymosin B4 AceTate)

  • Product Details

  • Seller Information

  • History Price

  • Inquiry History

  • Description


      Product Detail  


    Salesperson:zora

    whatsapp:+85269492373

    Email:zora@anymang.cn

    Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

    Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.

    In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.

    Retatrutide, LY3437943

    CAS#: 2381089-83-2

    Molecular Formula: C221H342N46O68

    Molecular Weight: 4731.33

    Sequence: H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

    Appearance: White Powder

    Purity (HPLC): ≥99.0%

    Single Impurity (HPLC): ≤1.0%

    Sodium Content (HPLC): 5.0%-12.0%

    Moisture Content (Karl Fischer): ≤10.0%

    Peptide Content: ≥80.0%

    Storage: Store at 2-8 degrees Celsius in a dry and cool place.

    Packaging: 1g-1kg, plastic bottle

    Intended Use: For scientific research purposes

    Items Specifications Items Specifications
    Model NO. Retatrutide Export Market Global 
    Quality Pharmaceutical grade Grade Pharmaceutical Grade
    Appearance White powder Transport Package Box
    Storage Dry and Cool Place Content Appearance 99
    Arrival Time 5-8 days Packaging 10mg/vial,10vials/box

    What is Retatrutide?

    Retatrutide (LY-3437943) is a drug in development to treat obesity and type 2 diabetes. This active compound activates receptor agonists in our bodies, helping with blood sugar control and weight loss management. Retatrutide is a glucagon-like peptide-1 (GLP-1) agonist, a new drug that also acts on another hormone called glucose-dependent insulnotropic polypeptide (GIP). These two hormones combined work wonders in promoting weight loss. But Retatrutide goes one step further; the drug also acts as a third hormone: glucagon.


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    Why choose us

    Our company has independent factories, mass production of pharmaceutical intermediates, organic intermediates and other raw materials, widely used in medicine, health care products, cosmetics, nutritional supplements, food additives and other fields.
    Our company adheres to the business philosophy of integrity and cooperation. scientific innovation and service first.With absolute quality assurance as the purpose and perfect service system as the basis, our company provides efficient and satisfactory consulting services, sincerely welcomes your business inquiries,and looks forward to working with you to create a new future.  
    Key Products:
    Our primary focus encompasses a range of products, including weight loss peptides, medicinal peptides, cosmetic peptides, and customized peptides. Notable among our weight loss peptide offerings are Semaglutide, Tirzepatide, Retatrutide, and others.

    Shop Retatrutide Lyophilized Hypoglycemic Cagrilintide trize sema Nad  for Weight Loss Peptides-Detailed Image 11 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 8 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 9 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 10 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 11 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 12 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 13 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 14 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 15 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 16 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 17 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 18 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 19 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 20 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 21 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 22 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 23 Shop Retatrutide | US Warehouse | GLP-1 GIP GCG Peptides | 99%Peptide Peptides Synthetic Peptide Research Peptide Lab Peptide Cosmetic Peptide Pharmaceutic-Detailed Image 24

    Mechanism of Action & Advantages

    Triple Receptor Agonist: As a triple agonist targeting GLP-1, GIP, and glucagon receptors, Retatrutide enables multi-pathway synergy to regulate blood glucose, energy expenditure, and appetite for comprehensive metabolic control.

    Potent Weight Loss & Glucose Control: Clinical data show its weight reduction and glycemic benefits are significantly superior to single or dual receptor agonists, offering a more robust treatment option for severe obesity and type 2 diabetes.

    Broader Metabolic Benefits: Beyond weight and glucose, studies indicate positive effects on cardiovascular metabolic markers like blood pressure and lipids.

    Clinical Trials & Safety Profile ​

    Phase II & III Clinical Trials: In multiple large-scale, randomized, double-blind, placebo-controlled trials, Retatrutide demonstrated outstanding efficacy:

    Achieved mean weight reduction exceeding 20% (over 24% in some subgroups) in patients with obesity.

    Significantly reduced HbA1c in type 2 diabetes patients alongside substantial weight loss.

    The overall safety profile is consistent with the GLP-1 receptor agonist class, with no new safety risks identified.

    Industry Recognition: Due to its breakthrough data, Retatrutide is recognized as a major advancement in obesity and diabetes treatment, with research published in leading medical journals.

    Items Specifications






    ECHEMI Editorial Reference
    Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.
    Retatrutide (LY-3437943) was discovered by the American pharmaceutical company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors) for obesity. The 2024 Lasker~DeBakey Clinical Medical Research Award has been given to Joel Habener and Svetlana Mojsov for their discovery of a new hormone GLP-1(7-37) and to Lotte Knudsen for her role in developing sustained acting versions of this hormone as a treatment for obesity.

    Certificates

    Basic Info
    Product Name:

    Retatrutide

    Other Name:

    Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

    CAS No.:

    2381089-83-2

    InChIKeys:

    MLOLQJNKXBNWFW-SAGGEDDASA-N

    Molecular Weight:

    0

    EC Number:

    200-001-8

    Color/Form:

    White lyophilized

    Characteristics
    Water Solubility:

    Soluble in water (5mg/ml).

    Storage Conditions:

    -20°C

    Critical Temperature & Pressure:

    -20°C

    Research
    Class:

    Triple agonist — GCGR, GIPR, GLP-1R

    Status:

    Investigational (Phase 3)

    Mechanism:

    Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

    EC50 (Human GCGR):

    5.79 nM

    EC50 (Mouse GIPR):

    0.191 nM

    EC50 (Mouse GLP1R):

    0.794 nM

    EC50 (Mouse GCGR):

    2.32 nM

    EC50 (Human GLP1R):

    0.775 nM

    EC50 (Human GIPR):

    0.0643 nM

    Source:

    Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

    Clinical Development:

    NCT04881760; NCT05882045; NCT06354660

    References
    ChEMBL:

    CHEMBL5095485

    DrugBank:

    DB18993

    KEGG DRUG:

    D12430

    PubChem:

    PubChem

    Disclaimer:

    Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Semag lutide,Tirzepatide,Retatrutide,raw material,GHK-CU,TB500(Thymosin B4 AceTate)

    Location:

    Room 1002-C3973, No. 80, Yongtai Modaonan Street, Yongping Subdistrict, Baiyun District, Guangzhou City

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    45 days

    Year of Establishment:

    2026

    Anymang is a US-based trading company dedicated to the global supply and formulation of high-quality cosmetic raw materials, with a core focus on peptide ingredients. Committed to bridging premium suppliers and beauty manufacturers worldwide, we deliver pure, stable, and efficacious peptides—including anti-aging, brightening, and firming peptides—alongside a full spectrum of cosmetic actives and custom formulation solutions. With rigorous quality control and compliance with US safety standards, we ensure consistent batch quality and reliable delivery. Our experienced team provides professional technical support and tailored services to help clients develop competitive skincare and personal care products. Trusted by partners across the globe, Anymang stands as your dependable partner for innovative, high-performance cosmetic raw materials and peptide formulations.

  • Weekly Price

    The chart shows the price trend of the product in the past 12 months.

  • Inquiry History
    7440 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Retatrutide 2381089-83-2

    3 MT Mar 28, 2026
    United Kingdom

    Retatrutide - 2381089-83-2

    1 G Feb 10, 2026
    United States

    Retatrutide CAS 2381089-83-2 10mg vial

    20 MT Mar 7, 2026
    United States

    Factory Retatrutide API 99% Purity CAS 2381089-83-2

    5 KG Nov 10, 2025
    United Kingdom

    Peptide powder Retatrutide 99% pure for Body building cas 2381089-83-2 Weight Loss Peptide with COA

    1 MT Mar 22, 2026
    United States

    2381089-83-2

    100 G Jul 14, 2026
    United States

    2381089-83-2

    100 G Feb 24, 2026
    United States

    2381089-83-2

    100 MT Dec 9, 2023
    United States

    Retatrutide 2381089-83-2

    200 MG May 16, 2026
    United Kingdom

    2381089-83-2 retatrutide

    300 MG Feb 13, 2026
    United States

    Retatrutide 2381089-83-2 wholesale

    500 MT Nov 3, 2023
    United States

    Retatrutide CAS 2381089-83-2 99%

    10 PCS Feb 21, 2026
    Poland

    CAS 2381089-83-2 (Custom Peptide)

    40 MT Apr 10, 2026
    Austria

    Peptide Retatruide CAS 2381089-83-2

    100 MT Apr 4, 2026
    Austria

    Retatrutide CAS 2381089-83-2 10mg vial

    20 PCS Feb 10, 2026
    United States

    GLP-1 / GIP Retatrutide cas 2381089-83-2

    1 MT Oct 16, 2024
    United States

    Retatrutide 99% High Quality CAS 2381089-83-2

    1 G Jan 23, 2026
    United States

    Injection Peptide Tirzepatide/Retatrutide/ Semaglutide Peptides CAS 2381089-83-2

    10  Oct 21, 2023
    Australia

    GMP Grade 99% Retatrutide Lyophilized Powder CAS 2381089-83-2

    10 G Jun 12, 2026
    Palestine

    Factory 99% Purity Retatrutide Peptide CAS 2381089-83-2 Door-To-Door Service

    10 MG Mar 16, 2026
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