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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Retatrutide for Sale > Peptide Buy Weight Loss Peptides Retatrutide Tirzepatide Semaglutide GLP-1 10mg 20mg Research Peptide
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Peptide Buy Weight Loss Peptides Retatrutide Tirzepatide Semaglutide GLP-1 10mg 20mg Research Peptide

TDS 7503 Inquiries

Unit Price: Get Latest Price
CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

guangzhou

Brand:

STTY

Packaging:

5 mg/vial, 10vial/kit;10 mg/vial,10vial/kit;15 mg/vial, 10vial/kit

Price valid (until):

2026-08-31

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
11 days
Qualification:
Main Products:

Peptide

  • Product Details

  • Seller Information

  • Inquiry History

  • Description

    Contact us: Whatsapp: 

    +852 9458 3732  

    +852 5504 0284 

    ------Product Detail------

    Basic Info.

    Shop Peptide Buy Weight Loss Peptides Retatrutide Tirzepatide Semaglutide GLP-1 10mg 20mg Research Peptide-Detailed Image 1

    I. Basic Information

    Full Name: Retatrutide (Research Code: LY3437943)

    CAS Number: 2381089-83-2
    Molecular Formula: C₂₂₁H₃₄₂N₄₆O₆₈
    Structure: A synthetic peptide of 39 amino acids with fatty acid side chains; half-life approximately 6 days.
    Purity: ≥99% (Research Grade)
    Appearance: White to off-white lyophilized powder


    II. Mechanism of Action (Triple Receptor Agonist)
    Simultaneously activates three major metabolic receptors: GLP-1 + GIP + Glucagon (GCG):

    GLP-1: Lowers blood sugar, suppresses appetite, delays gastric emptying

    GIP: Enhances insulin secretion, increases satiety

    GCG: Promotes fat breakdown, increases energy expenditure, reduces liver fat

    Comparison: Semaglutide (single receptor), Tirzepatide (dual receptor), Retatrutide (triple receptor)


    III. Core Efficacy (Phase III Clinical Data, 2026)

    Powerful Weight Loss (TRIUMPH-1, 80 weeks)

    4 mg: Average weight loss 15%

    9 mg: Average weight loss 22%

    12 mg: Average weight loss 24–30% (up to 30% in severely obese individuals)
    83% of weight loss is fat, muscle is preserved

    Significant Blood Sugar Reduction: Significantly reduces HbA1c in type 2 diabetes patients, some approaching normal levels

    Comprehensive Metabolic Improvement: Lowers triglycerides, non-digestive enzymes... HDL-C reduces inflammatory factors (hsCRP) and improves fatty liver (MASH). Benefits include: Knee osteoarthritis: 76% improvement in pain score and functional enhancement; Improvement in sleep apnea, chronic low back pain, etc.


    IV. Specifications and Usage (Research/Reagent Grade)
    Common Specifications: 5 mg/vial, 10 mg/vial (lyophilized)
    Reconstitution: Dilute with 3 ml or 10 ml of **bacteriostatic water**.

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    Packaging & Shipping   

    Shop Peptide Buy Weight Loss Peptides Retatrutide Tirzepatide Semaglutide GLP-1 10mg 20mg Research Peptide-Detailed Image 5


    Create win-win situation with customers

         Our main products include peptide products and pharmaceutical raw materials. We boast strong R&D capabilities, superb synthesis technology, and advanced quality control methods. We actively promote joint ventures and cooperation with major enterprises and manufacturers, serving society and users with the concept of industrial development. We always adhere to market demand orientation and continuously develop new high-tech chemical products and pharmaceutical intermediates.

         I am very confident in the quality of our products, and many foreign customers have given high praise after receiving our goods. Our products are of excellent quality, and we firmly guarantee door-to-door delivery of your orders.


    Corporate Culture:Strive for survival by quality, strive for development by competition


    Corporate Philosophy:We always adhere to "integrity-based, customer first, high quality and efficiency" as the concept, based on "excellent quality, transparent price, punctual delivery, professional service" as the principle, meanwhile we can and will do our best to provide customers with the best service to repay customers.

    Shop Peptide Buy Weight Loss Peptides Retatrutide Tirzepatide Semaglutide GLP-1 10mg 20mg Research Peptide-Detailed Image 6


    ------FAQ------

    Which payment is available for your company?

    Bank Transfer,Paypal or Bitcoins usdt trc usdt erc and so on.  You can choose the way which is convenient for you.

    May I get one sample before placing order?

    Yes, Sample are available. For normal products, samples are for free and you just need to bear the freight; For those high value products, you just need to freight and certain product cost. When we both cooperate for some times or when you are our VIP customer, free sample will be offered when you need.Mutual effort towards each other.

    Why should you buy from us not from other suppliers?

    1. Powerful R & D team
    2. The ability of quantized production from grams to tons;
    3. Various kinds of advanced equipment in the laboratory and plant;
    4 .Strict QC standard to meet the demand of customers, advanced equipment for analysis and assay;
    5. Efficient and safe logistic plans for chemical products transportation;
    6 .Excellent after-sale service.
    7. Highest quality and good package
    8 .ISO certificate

    Items Specifications
    Product name Retatrutide
    Appearance white powder
    purity 99%
    Package 10 vials/box
    shelf life 2 years
    ECHEMI Editorial Reference
    Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.
    Retatrutide (LY-3437943) was discovered by the American pharmaceutical company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors) for obesity. The 2024 Lasker~DeBakey Clinical Medical Research Award has been given to Joel Habener and Svetlana Mojsov for their discovery of a new hormone GLP-1(7-37) and to Lotte Knudsen for her role in developing sustained acting versions of this hormone as a treatment for obesity.

    Certificates
    • Peptide Buy Weight Loss Peptides Retatrutide Tirzepatide Semaglutide GLP-1 10mg 20mg Research Peptide Certificates 2 TDS

    Basic Info
    Product Name:

    Retatrutide

    Other Name:

    Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

    CAS No.:

    2381089-83-2

    InChIKeys:

    MLOLQJNKXBNWFW-SAGGEDDASA-N

    Molecular Weight:

    0

    EC Number:

    200-001-8

    Color/Form:

    White lyophilized

    Characteristics
    Water Solubility:

    Soluble in water (5mg/ml).

    Storage Conditions:

    -20°C

    Critical Temperature & Pressure:

    -20°C

    Research
    Class:

    Triple agonist — GCGR, GIPR, GLP-1R

    Status:

    Investigational (Phase 3)

    Mechanism:

    Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

    EC50 (Human GCGR):

    5.79 nM

    EC50 (Mouse GIPR):

    0.191 nM

    EC50 (Mouse GLP1R):

    0.794 nM

    EC50 (Mouse GCGR):

    2.32 nM

    EC50 (Human GLP1R):

    0.775 nM

    EC50 (Human GIPR):

    0.0643 nM

    Source:

    Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

    Clinical Development:

    NCT04881760; NCT05882045; NCT06354660

    References
    ChEMBL:

    CHEMBL5095485

    DrugBank:

    DB18993

    KEGG DRUG:

    D12430

    PubChem:

    PubChem

    Disclaimer:

    Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptide

    Location:

    Room 1501, Building 1, Changnan Mansion, Country Garden, on the west side of Taoyang North Road

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    11 days

    Year of Establishment:

    2025

  • Inquiry History
    7503 Inquiries
    Country Product Purchase Quantity Date Posted
    Malaysia

    Retatrutide

    20 MG Oct 28, 2026
    Australia

    Retaturtide

    100 MG Oct 29, 2026
    United States

    Retatrutide 30mg and 50mg

    20 PCS Oct 29, 2026
    Belgium

    Retatrutide

    1 MG Oct 29, 2026
    Romania

    Retatrutide

    10 G Oct 29, 2026
    United States

    Retatrutide

    2 MT Oct 29, 2026
    United States

    Retatrutide

    1 MT Oct 29, 2026
    United Kingdom

    Retatrutide

    1 PCS Oct 28, 2026
    United States

    Retatrutide

    30 MT Oct 28, 2026
    United Kingdom

    Retatrutide

    10 MT Oct 28, 2026
    United States

    retatrutide

    30 MG Oct 28, 2026
    Czech

    Retatrutide

    10 MG Oct 28, 2026
    Austria

    retatrutide

    30 MG Oct 28, 2026
    United States

    Retatrutide

    100 KG Oct 28, 2026
    Malta

    Retatrutide

    10 MT Oct 28, 2026
    United States

    Retatrutide

    600 MG Oct 28, 2026
    United States

    Retatrutide

    500 G Oct 28, 2026
    United States

    Retatrutide

    60 G Oct 28, 2026
    Croatia

    Retatrutide

    10 MG Oct 28, 2026
    United States

    Retatrutide

    200 MG Oct 28, 2026
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