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I. Basic Chemical Identification

• Common Name: Semax
• Amino Acid Sequence: Met-Glu-His-Phe-Pro-Gly-Pro (linear heptapeptide)
• CAS Registry Number: 80714-61-0
• Molecular Weight: 813.92 Da
• Molecular Formula: C₃₇H₅₁N₉O₁₀S

II. Key Physicochemical Properties

• Appearance: White to off-white loose powder, no visible foreign matter
• Solubility: Soluble in purified water, slightly soluble in organic solvents
• Stability: Stable in a dark, sealed and dry environment; long-term storage is recommended at -20℃ frozen

III. Synthesis & Quality Standards

Synthesis Process: Adopting standard Fmoc Solid-Phase Peptide Synthesis (SPPS) with mature and controllable process

• HPLC Purity: ≥98.0% (≥99.0% for research grade)
• Key Indicators: Qualified amino acid composition, moisture ≤10.0%, heavy metal (Pb) ≤10 ppm

IV. Storage & Transportation Requirements

• Packaging: Sealed packaging with built-in desiccant and  protection to ensure stability
• Storage: Frozen at -20℃, protected from light and moisture, avoiding high temperature
• Transportation: General cargo channel, properly insulated to avoid damage

V. Applications & Specifications

• Main Applications: Life science research; R&D of fine chemical intermediates
• Specifications: Marked "For Research/Chemical Raw Material Use Only", complying with relevant industrial standards

Description:

• MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a small peptide that originates from the mitochondria, the energy-producing organelles within cells. It plays a key role in regulating metabolism, cellular energy production, and age-related health issues. MOTS-C is part of a class of peptides known as mitokines, which are molecules produced by mitochondria that influence cellular functions and systemic processes.

  Regulation of Metabolism:

  MOTS-C helps regulate glucose metabolism and sensitivity, making it a key player in blood sugar regulation and potentially helpful in managing conditions like type 2 diabetes.
  Promotes Fat Loss:

  MOTS-C has been shown to enhance fat oxidation, which could support weight loss and prevent excessive fat accumulation, especially in the context of aging or metabolic disorders.
  Increases Energy Production:

  By boosting mitochondrial function, MOTS-C helps improve cellular energy production, potentially reducing fatigue and increasing overall vitality, particularly in aging individuals.
  Anti-Aging Properties:

  MOTS-C is thought to have anti-aging effects by improving metabolic health, protecting against oxidative stress, and enhancing the body's ability to handle the stress associated with aging.
  Improves Exercise Performance:

  Some studies suggest that MOTS-C can enhance physical performance and endurance by increasing the efficiency of energy use within cells, potentially improving athletic performance and recovery.
  Supports Muscle Health:

  MOTS-C may play a role in maintaining muscle mass and improving muscle function, particularly in older adults, by modulating mitochondrial function and muscle metabolism.
  

  Semax is an experimental drug that was originally developed back in Russia to prevent and treat circulatory disorders. It has also been identified as a “nootropic” or “cognitive enhancer.”

  Also known as the Heptapeptide SEMAX (MEHFPGP), it is the analog of ACTH. It has been seen to demonstrate prolonged neuropathic activity.

  Historically, it has been used in patients experiencing pathologies connected to brain circulation dysfunction. This has also been suggested in literature because of its effects on carboxypeptidase which may increase physical performance and adaptation capacities in exposure due to high intensity and exercises at high doses.