Tipranavir RC09313
174484-41-4
Pharmaceutical Grade
99%
Royalchem
25kg/drum
Yes
2030-01-01
Pharmaceutical intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceTipranavir is a pyridine-2-sulfonamide substituted at C-5 by a trifluoromethyl group and at the sulfonamide nitrogen by a dihydropyrone-containing m-tolyl substituent. It is an HIV-1 protease inhibitor. It has a role as a HIV protease inhibitor and an antiviral drug.|Tipranavir is a sulfonamide-containing dyhydropyrone and a nonpeptidic protease inhibitor that targets the HIV protease. Tipranavir and ritonavir are coadministered to treat HIV.|Tipranavir is a Protease Inhibitor. The mechanism of action of tipranavir is as a HIV Protease Inhibitor.|Tipranavir is an antiretroviral protease inhibitor used in the therapy and prevention of human immunodeficiency virus (HIV) infection and the acquired immunodeficiency syndrome (AIDS). Tipranavir can cause transient and usually asymptomatic elevations in serum aminotransferase levels and is a rare cause of clinically apparent, acute liver injury. In coinfected patients, hepatic injury during highly active antiretroviral therapy including tipranavir may be a result of exacerbation of the underlying chronic hepatitis B or C, rather than a direct effect of the medication.|Tipranavir is a non-peptidomimetic agent that inhibits both wild type and drug resistant forms of human immunodeficiency virus (HIV) protease.Basic Info
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Product Name:
Tipranavir
Other Name:2-Pyridinesulfonamide,N-[3-[(1R)-1-[(6R)-5,6-dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)-;2-Pyridinesulfonamide,N-[3-[1-[5,6-dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)-,[R-(R*,R*)]-;N-[3-[(1R)-1-[(6R)-5,6-Dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)-2-pyridinesulfonamide;U 140690;PNU 140690;Tipranavir;Aptivus;TPV
CAS No.:174484-41-4
Molecular Formula:C31H33F3N2O5S
InChIKeys:InChIKey=SUJUHGSWHZTSEU-FYBSXPHGSA-N
Molecular Weight:602.66400
Exact Mass:602.66
UNII:ZZT404XD09
DSSTox ID:DTXSID6048622
NCI Thesaurus Code:C66603
Color/Form:White solid from ethyl acetate + heptane
ATC Code:J05AE09|J - Antiinfectives for systemic use
Categories:
Characteristics-
PSA:
113.97000
XLogP3:8.47930
Appearance:White Solid
Density:1.313g/cm3
Melting Point:86-89 °C
Boiling Point:680ºC
Flash Point:365.1ºC
Refractive Index:1.579
Water Solubility:Insoluble|In water, 7.17X10-6 mg/L at 25 °C (est)|Freely soluble in dehydrated alcohol, propylene glycol. Insoluble in aqueous buffer, pH 7.5
Vapor Pressure:0mmHg at 25°C
Henrys Law Constant:Henry's Law constant = 2.63X10-14 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa = 5.86 (hydroxyl) (est)
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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