Hydroxypropyl methyl cellulose
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Hydroxypropyl methyl cellulose
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CAS No:
9004-65-3
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Formula:
C3H8O2.xCH4O.xUnspecified
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Chemical Name:
Hydroxypropyl methyl cellulose
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Synonyms:
Cellulose,2-hydroxypropyl methyl ether;Hydroxypropyl methyl cellulose ether;Methocel X 2602;Methyl hydroxypropyl cellulose;Cellulose hydroxypropyl methyl ether;Methocel HG 65;Methocel HG 60;Methofas PM;Methocel HG;Courlose HPM;Methocel J 12HS;Methocel HG 90;2-Hydroxypropyl methyl cellulose;Methofas PM 4500;Celacol HPM 450;Methocel E;Methocel F;Methocel K;Pharmacoat 603;Methocel 60HG4000;Celacol HPM 5000;HPMC 20000PV;Pharmacoat 606;TC 5R;Methocel XD 1214;Methocel XD 1214.44;Methocel HG 228;Methocel K 4M Premium;Methocel K 4M;Metolose 90SH4000;Methocel 50;MOPTs;Metolose 60SH50;Methocel 228;Synchron-Oral;Methocel F 4M;Methocel K 15M-DGS;MC 400;Metolose 90SH15000;Methocel E 15;Culminal MHPC;Methocel F 7M;Culminal MHPC 6000;TC 5;Metolose 90SH100;Synchron;Methocel K 100M;Methocel E 5;Methocel J;Methocel E 15LV;Methocel E 50;Methocel K 100;Methocel E 4M;Methocel MK 4;Metolose 90SH30000;Celacol HPM 15000DS;Metolose 65SH50;Methocel J 75MS;Metolose 65SH400;Methocel J 75;Methocel K 15MS;Metolose SH 4000;Hypromellose;Viscontran MHPC 50;Marpolose MP 4000;Metolose 60SH4000;Methocel J 5MS;Methocel F 50;2-Hydroxypropyl methyl cellulose ether;Methocel 90HG40;Walocel MW 60GA;Walocel MK 3.000PF;Culminal MHPC 20000PR;Methocel K 4MS;Metolose 90SH3000;Metolose 65SH4000;Hydroxypropyl methyl cellulose;Marpolose 60MP5;Celacol 15000DS;Methocel K 15M;Metolose 65SH1500;TC 5E;Methofas PM 450;8063-82-9;11106-33-5;12673-53-9;37341-76-7;39363-71-8;59029-31-1;62683-26-5;65607-39-8;68073-10-9;71373-07-4;98112-80-2;125053-98-7;125857-43-4;137397-89-8;137397-90-1;137397-91-2;171544-38-0;173080-61-0;194615-25-3;876407-53-3;1262284-64-9;2227180-04-1;2258661-54-8;2376293-65-9
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CAS No:
Description
Hypromellose is a water-soluble hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices.
Characteristics
0.00000
White to cream powder
1.326 g/cm3
225-230 °C
H2O: 50 mg/mL, clear to very faintly turbid, faintly yellow
Hypromellose powder is a stable material, although it is hygroscopic
after drying.
Solutions are stable at pH 3–11. Hypromellose undergoes a
reversible sol–gel transformation upon heating and cooling,
respectively. The gelation temperature is 50–90°C, depending
upon the grade and concentration of material. For temperatures
below the gelation temperature, viscosity of the solution decreases
as temperature is increased. Beyond the gelation temperature,
viscosity increases as temperature is i
Safety Information
NONH for all modes of transport
1
24/25
NF9125000
Stable. Solid is combustible, incompatible with strong oxidizing agents.
Hydroxypropyl methyl cellulose Use and Manufacturing
It is made from cellulose, methyl chloride and ethylene oxide.
As emulsifier, film former, protective colloid, stabilizer, suspending agent, or thickener in foods.Pharmaceutic aid (suspending agent; tablet excipient; demulcent; viscosity increasing agent); hydrophilic carrier in drug delivery systems.In adhesives, asphalt emulsions, caulking compounds, tile mortars, plastic mixes, cements, paints.
Price Analysis
- Data: 2026-07-22
- Price: 12000.00Yuan/ton
- Change: 0
Drug Function and Efficacy
Hydroxypropyl methylcellulose is a partial methyl and partial polyhydroxypropyl ether of cellulose, which can be dissolved in cold water to form a solution with a certain viscosity. Its properties are similar to the viscoelastic substances (mainly mucin) in tears, and it can be used as artificial tears. Through the adsorption of polymers, it attaches to the surface of the eyeball to simulate the effect of conjunctival mucin, improves the state of reduced eye mucin, and increases the retention time of the eyeball under the state of reduced tears. This adsorption effect is independent of the viscosity of the solution, ensuring that low-viscosity solutions also have a lasting wetting effect. In addition, it can also reduce the contact angle of the clean corneal surface to increase the corneal wetting effect and improve the stability of the precorneal tear film.
Registered Holders
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HUZHOU ZHANWANG PHARMACEUTICAL CO LTD
Active
United States
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THE DOW CHEMICAL COMPANY
Active
China
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Meixinjia Zhongwei Pharmaceutical Co., Ltd.
Active
China
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