High quality bestseller10mg -TB500- peptide bulk supply, 99% pure powder
1 Inquiries
1566590-77-9
Pharmaceutical Grade
99%
Guangzhou
Chunqiao
5mg 10mg
2026-07-05
peptide
-
Product Description
-
Seller Information
-
Inquiry History
-
DescriptionECHEMI Editorial ReferenceAfamelanotide, a synthetic α-melanocyte stimulating hormone analog and first-in-class melanocortin-1 receptor agonist, has been approved in the EU for the prevention of phototoxicity in adults with erythropoietic protoporphyria (EPP)[1].Basic Info
-
Product Name:
Afamelanotide acetate
Other Name:(Nle4,D-Phe7)-α-MSHAfaMelanotide, NDP-MSH, Melanotan 1, CUV1647;Afamelanotide acetate;Afamelanotide acetate, 10 mM in DMSO;Melanotan I acetate :Melanotan I;Melanotan 1 acetate
CAS No.:1566590-77-9
Molecular Formula:C80H115N21O21
InChIKeys:LBIUKNXYUXOWFF-CRYSLBJVSA-N
Molecular Weight:1706.93
Exact Mass:1705.85763976
EC Number:590-177-9
Categories:
Research-
Class:
Actin-sequestering protein / 43-amino-acid peptide
Status:Research compound — Not FDA approved (investigational: RGN-259 for dry eye / neurotrophic keratitis)
Mechanism:A naturally occurring 43-amino-acid peptide (Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH) that binds G-actin (sequesters monomeric actin), preventing F-actin polymerization. Promotes cell migration, angiogenesis, wound healing, and anti-inflammatory responses via integrin-linked kinase (ILK) and HIF-1α/VEGF pathways. TB-500 is the synthetic fragment Ac-LKKTETQ (MW ~895) often sold under this CAS.
Activity note:Thymosin Beta-4 is an actin-binding protein, not a receptor agonist. Functional activity is measured by actin sequestration (Kd ~0.7–1 μM) and cell migration assays, not EC₅₀.
Source:Goldstein AL, et al. Vitam Horm. 2003;66:257–296. RegeneRx RGN-259 clinical program.DOI
Clinical Development:
References-
DrugBank:PubChem:UNII:Disclaimer:
Thymosin Beta-4 (TB-500) is NOT FDA-approved for human therapeutic use. RGN-259 (Tβ4 ophthalmic solution) is an investigational drug not yet approved. TB-500 sold on research-chemical marketplaces is a synthetic fragment and is not an approved medicine. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
-
-
Seller Information
-
Business Type:
Trader
-
Main Products:
peptide
-
Location:
Unit 1-B2141, 19B-F1, 81-1 Nonglinxia Road, Yuexiu District, Guangzhou, China
-
Year of Establishment:
2026
-
-
Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
Pakistan
Afamelanotide CAS1566590-77-9
1 G Jan 27, 2025 Post an enquiry for this product
More from this Seller
-
-
-
Sterile Tirzepatide Lyophilized Reagent For GIP GLP-1 Metabolic Research
Cosmetics Grade / 99%
$43/UNIT EXW
-
-
-
-
Cibinetide ARA-290 Peptide 10mg Vials Erythropoietin Derivative Research
Cosmetics Grade / 99%
$80/UNIT EXW
-
-
-
-
Dulaglutide 5mg Vials Long Acting GLP-1 Agonist Fc Fusion Peptide
Cosmetics Grade / 99%
$115/UNIT EXW
-
-
-
-
Cyanocobalamin Vitamin B12 1ml Vials Red Liquid Supplement 5000mcg
Cosmetics Grade / 99%
$110/UNIT EXW
-
-
-
-
KPV Tripeptide 5mg Vials Alpha MSH Fragment Anti-Inflammatory Peptide
Cosmetics Grade / 99%
$45/UNIT EXW
-
-
-
-
Top Grade Best Peptide,99% High Purity Level white raw powder in stock 100mg
Pharmaceutical Grade / 99.9%
-