99% Purity TSM10 safe Global Shipping and Custom Packaging 5mg*10vials/10mg*10vials/20mg*10vials

  Product Detail  

SM is a potent, synthetic growth hormone–releasing factor (GHRF) analogue that specifically stimulates the synthesis and release of endogenous growth hormone. It effectively reduces visceral abdominal fat, improves body composition, enhances lipid metabolism, and supports healthy metabolic function. It also helps maintain muscle mass, boosts energy levels, promotes physical recovery, and supports overall metabolic wellness. With high purity, reliable stability, and good safety, TSM is widely used in endocrine research, metabolic health studies, body composition management, and biomedical raw material applications.

Name:Rain

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Email:rain@anymang.cn

Triple Agonist Design :

GLP-1 receptor: Retatrutide delays gastric emptying, suppress appetite, and promote secretion.

GIP receptor: Retatrutide enhances sensitivity and regulate central satiety signals.

Glucagon receptor (GCGR): Retatrutide activates liver energy metabolism, promote lipolysis and glycogenolysis, and increase basal metabolic rate.

The triple synergistic effect increases energy consumption while reducing energy intake, significantly improving weight loss effects.

Mechanism of Action and Molecular Structure of Retatrutide:

1)Triple Agonist Design
- GLP-1 receptor: Retatrutide delays gastric emptying, suppress appetite, and promote secretion.
- GIP receptor: Retatrutide enhances insulin sensitivity and regulate central satiety signals.
- Glucagon receptor (GCGR): Retatrutide activates liver energy metabolism, promote lipolysis and glycogenolysis, and increase basal metabolic rate.
The triple synergistic effect increases energy consumption while reducing energy intake, significantly improving weight loss effects.

2) Structural Optimization
- Based on the GIP skeleton modification, non-natural amino acids (such as α-methylleucine at position 13) are introduced to enhance receptor affinity.
- The half-life is extended to 7 days through fatty acid side chain modification