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Home > Biochemical Engineering > Inhibitors > Suzetrigine for Sale > Suzetrigine(VX548) cas 2649467-58-1 lab use for research
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Suzetrigine(VX548) cas 2649467-58-1 lab use for research

10 Inquiries

Unit Price: Get Latest Price
CAS No.:

2649467-58-1

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

/

Packaging:

bag

Price valid (until):

2026-07-07

Company Type:
Trader
Location:
China
Qualification:
Main Products:

3-(1-Naphthoyl)indole

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Suzetrigine (VX-548), marketed as Journavx, is an orally administered selective NaV1.8 inhibitor approved by the FDA for the treatment of moderate to severe acute pain in adults. NaV1.8 is a voltage-gated sodium channel that plays a crucial role in transmitting pain signals and is selectively expressed in peripheral pain receptors and dorsal root ganglia.

    Mechanism of Action: Suzetrigine intervenes in the pain signal transduction pathway by highly selectively inhibiting NaV1.8 channels, reducing pain before the signal reaches the brain. This mechanism of action involves blocking peripheral pathways.

    Action: VX-548 is an orally active and highly selective NaV1.8 inhibitor with analgesic effects.


    1. Consignee name: Mr.lucas
    2. Phone/what3pp:86 15053178817
    3. E mail:lucas@tf-chemi.com


    Basic Info
    Product Name:

    Suzetrigine

    Other Name:

    2-Pyridinecarboxamide, 4-[[[(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)tetrahydro-4,5-dimethyl-5-(trifluoromethyl)-2-furanyl]carbonyl]amino]-;Suzetrigine;VX-548(Suzetrigine);4-[(2R,3S,4S,5R)-3-(3,4-Difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carboxamido]picolinamide;(2R,3S,4S,5R)-4-[[3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carbonyl]amino]pyridine-2-carboxamide;SUZETRIGINE/VAX548;FANDACHEM VX-548;FANDACHEM Suzetrigine

    CAS No.:

    2649467-58-1

    Molecular Formula:

    C21H20F5N3O4

    InChIKeys:

    XSQUJFKRXZMOKA-KRZZIQMTNA-N

    Molecular Weight:

    473.4

    EC Number:

    200-100-8

    Color/Form:

    White to light yellow

    Categories:

    Inhibitors

    Characteristics
    Density:

    1.399±0.06 g/cm3(Predicted)

    Boiling Point:

    591.8±50.0 °C(Predicted)

    PKA:

    11.74±0.70(Predicted)

  • Seller Information
    Business Type:

    Trader

    Main Products:

    3-(1-Naphthoyl)indole

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Inquiry History
    10 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Suzetrigine

    2 KG Jul 9, 2025
    Bangladesh

    Suzetrigine

    30 G Nov 18, 2024
    Bangladesh

    SUZETRIGINE

    1 KG Mar 25, 2026
    Turkey

    Suzetrigine

    2 KG Jul 2, 2025
    Russia

    Suzetrigine

    25 KG Feb 17, 2026
    United States

    suzetrigine

    1 KG Sep 13, 2025
    Turkey

    Suzetrigine

    2 KG Jul 9, 2025
    Turkey

    Suzetrigine

    2 KG Jul 2, 2025
    Pakistan

    SUZETRIGINE

    1 KG Jun 5, 2025
    Pakistan

    SUZETRIGINE

    1 KG May 27, 2025
    Post an enquiry for this product
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