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4alpha,8beta-Dihydroxyeudesm-7(11)-en-12,8-olide

Name: 4alpha,8beta-Dihydroxyeudesm-7(11)-en-12,8-olide
Brand: Cuicheng Bio
SKU: pr2606081092
Price: 300000 USD
Availability: InStock

Unit Price:

$300000-350000/G FOB

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CAS No.:

1231208-53-9

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

5mg

Price valid (until):

2026-07-08

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
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Description

4α,8β-Dihydroxyeudesm-7(11)-en-12,8-olide (CAS 1231208-53-9) functions primarily as a bioactive natural product, phytomedicinal reference standard, and molecular probe in pharmacological research.

Classified as a eudesmane-type sesquiterpene lactone, it is naturally synthesized by plants like Chloranthus elatior and Chloranthus japonicus. Like many related eudesmanolides, it exhibits notable biological properties being actively explored in drug discovery.

Core Functions and Research Applications

Anti-Inflammatory Screening: In biochemical assays, compounds of this sesquiterpene class function as potent anti-inflammatory agents. They inhibit the expression of inducible nitric oxide synthase (iNOS) and downregulate major pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukins (IL-1β, IL-6).
Oncology Research (Cytotoxicity & Apoptosis): This molecular skeleton is highly investigated for its anticancer properties. Related structures function by inducing cell cycle arrest, triggering the depolarization of mitochondrial membrane potentials, and activating cleaved caspase-3 to drive apoptotic pathways in cancer cell lines.
Phytochemical Reference Standard: Because it serves as a chemical marker for the Chloranthus genus, high-purity forms of this molecule (≥98%) are used in analytical chemistry—such as High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS)—to profile, standardize, and verify the quality of herbal extracts.
Enzyme Inhibition Studies: It serves as a testing substrate to evaluate enzyme-inhibiting properties common to plant terpenoids, particularly against enzymes related to neurodegenerative and metabolic pathways.

Basic Info

Product Name:

4,8-Dihydroxyeudesm-7(11)-en-12,8-olide

Other Name:

4,8-Dihydroxyeudesm-7(11)-en-12,8-olide

CAS No.:

1231208-53-9

Molecular Formula:

C15H22O4

Exact Mass:

266.151794

Categories:

Sesquiterpene

Characteristics

PSA:

66.76000

XLogP3:

0.66

Density:

1.3±0.1 g/cm3

Boiling Point:

456.4±45.0 °C at 760 mmHg

Flash Point:

170.6±22.2 °C

Refractive Index:

1.570

See More 4,8-Dihydroxyeudesm-7(11)-en-12,8-olide Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 4,8-Dihydroxyeudesm-7(11)-en-12,8-olide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

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4alpha,8beta-Dihydroxyeudesm-7(11)-en-12,8-olide

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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