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cis-Methylisoeugenol

Unit Price:

$160000-180000/G FOB

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CAS No.:

6380-24-1

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

5mg

Price valid (until):

2026-07-08

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

  • Product Description

  • Seller Information

  • Description
    cis-Methylisoeugenol (chemically known as (Z)-1,2-dimethoxy-4-(prop-1-en-1-yl)benzene) is a naturally occurring phenylpropanoid alkene compound. As a methylated derivative of isoeugenol, it is widely distributed within the volatile essential oils of aromatic plants such as Asarum (wild ginger), Acorus calamus (sweet flag), and Cymbopogon winterianus (Java citronella).
    Due to the specific spatial configuration of its cis- double bond, it exhibits distinct physical and biological properties compared to its more stable trans- isomer. Its primary functions span smooth muscle relaxation, premium fragrance compounding, plant chemical defense, and mucous dissolution.
    1. Core Biological and Pharmacological Functions
    • Smooth Muscle Relaxation and Antispasmodic Activity: In biomedical and metabolomic models, methylisoeugenol functions as a potent smooth muscle relaxant. It helps modulate internal muscle tone, making it a valuable target of interest for researching therapies against Irritable Bowel Syndrome (IBS), painful menstrual cramps (dysmenorrhea), and sudden gastrointestinal spasms.
    • Mucolytic Agent and Respiratory Relief: Specialized metabolomic whitepapers highlight the role of this lipophilic molecule as an effective mucolytic agent. When deployed in respiratory pathways, it thins and loosens heavy, accumulated mucus, assisting in the clearance of airway secretions to help relieve chest tightness and shortness of breath caused by coughs, colds, and bronchitis.
      • Antifungal and Anti-Infective Efficacy: It displays clear antifungal properties against Candida albicans and other opportunistic pathogens. It operates by penetrating and disrupting the structural integrity of fungal cell membrane barriers, serving as an active monomer candidate in natural therapeutic screening for oral thrush or yeast infections.
      • Antioxidant and Cellular Cytoprotection: The dimethoxybenzene ring within its structure offers electron-donating capabilities, giving the molecule a baseline free radical scavenging profile. In cell assays, it aids in downregulating the activation of pro-inflammatory cascades (such as the NF-κB pathway), protecting tissue grids from localized oxidative degradation.
      2. Commercial Fragrance and Food Industry Functions
      • Premium "Carnation-Note" Aromatic Fixative: In the fragrance and perfumery industry, cis-methylisoeugenol is a highly valued raw material. It naturally delivers a sweet, warm, mildly spicy, and herbaceous tea-like scent profile that mimics the luxury carnation or clove blossom aroma.
      • Safe Alternative to Isoeugenol: Because pure isoeugenol is strictly restricted by the International Fragrance Association (IFRA) due to dermal sensitization risks, the methylated cis-methylisoeugenol is widely used as a safe scent fixative in fine perfumes (such as rose, ylang-ylang, and oriental blends) and high-end skincare formulations because it carries a significantly lower risk of skin allergy.
        • Food Flavor Enhancer: It is officially approved as a safe flavoring additive for food, beverages, baked goods, and chocolates to enrich and stabilize the taste profiles of vanilla, berries, and complex spices.
        3. Ecological Allelopathy and Agricultural Pest Management
        • Insect Attractant and Chemical Weapon: In wild ecosystems, plants deploy this compound as a secondary metabolite to interact with their environment—either to attract specific pollinators or to repel predators. Because it possesses an intense olfactory pull on specific destructive agricultural pests (such as male fruit flies), it is widely utilized by agricultural scientists as a natural active ingredient in eco-friendly insect traps to manage crop infestations.
        4. Analytical Chemistry and Synthetic Utility
        • Isomeric Quality Reference Standard: In natural product discovery, high-purity cis-methylisoeugenol is used as a validated analytical reference standard. Analysts employ it in Gas Chromatography-Mass Spectrometry (GC-MS) to accurately determine the purity, isomer ratios, and quality control baselines of commercial essential oils. It also functions as a reactive electrophilic intermediate to synthesize more complex polyphenolic drug backbones.


    Basic Info
    Product Name:

    cis-Methylisoeugenol

    Other Name:

    Benzene,1,2-dimethoxy-4-(1Z)-1-propen-1-yl-;Benzene,1,2-dimethoxy-4-propenyl-,(Z)-;Benzene,1,2-dimethoxy-4-(1-propenyl)-,(Z)-;Benzene,1,2-dimethoxy-4-(1Z)-1-propenyl-;Veratrole,4-propenyl-,cis-;1,2-Dimethoxy-4-(1Z)-1-propen-1-ylbenzene;cis-Methylisoeugenol;cis-Isoeugenol methyl ether;4-cis-Propenylveratrole;(Z)-3,4-Dimethoxy-β-methylstyrene;(Z)-Methylisoeugenol;(Z)-O-Methylisoeugenol;1,2-Dimethoxy-4-(1-cis-propenyl)benzene;1,2-Dimethoxy-4-(1′-Z-propenyl)benzene;cis-O-Methylisoeugenol;(Z)-1,2-Dimethoxy-4-(prop-1-en-1-yl)benzene

    CAS No.:

    6380-24-1

    Molecular Formula:

    C11H14O2

    InChIKeys:

    InChIKey=NNWHUJCUHAELCL-PLNGDYQASA-N

    Molecular Weight:

    178.23

    Exact Mass:

    178.23

    Categories:

    Phenylpropanoids

    Characteristics
    PSA:

    18.46000

    XLogP3:

    3.05

    Appearance:

    colourless to pale yellow liquid; delicate, clove-carnation aroma

    Density:

    1.0±0.1 g/cm3

    Melting Point:

    70 °C

    Boiling Point:

    270.5 °C

    Flash Point:

    104.5±21.3 °C

    Refractive Index:

    1.534

    Water Solubility:

    Insoluble in glycerine and propylene glycol; soluble in most fixed oils

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

    Location:

    Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    51-100

    Year of Establishment:

    2019

  • Country Product Purchase Quantity Date Posted
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