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D-Fructose-6-phosphate

Name: D-Fructose-6-phosphate
Brand: Cuicheng Bio
SKU: pr2606081176
Price: 1000 USD
Availability: InStock

Unit Price:

$1000-1200/G FOB

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CAS No.:

643-13-0

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

1mg

Price valid (until):

2026-07-08

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
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Description

D-Fructose-6-phosphate (F6P), often called Neuberg ester, is a fundamental phosphorylated sugar intermediate that primarily functions as a major crossing hub connecting glycolysis, gluconeogenesis, and the pentose phosphate pathway. It is present in all living cells and is vital for cellular energy production and macromolecule synthesis.

Core Biological and Metabolic Functions

Central Checkpoint in Glycolysis: F6P acts as the direct substrate for phosphofructokinase-1 (PFK-1), the primary rate-limiting and committed step of glycolysis. PFK-1 phosphorylates F6P into fructose-1,6-bisphosphate, driving the cell toward energy (ATP) generation.
Key Intermediate in Gluconeogenesis: When cells need to synthesize glucose from non-carbohydrate sources (like during fasting), the enzyme fructose-1,6-bisphosphatase converts fructose-1,6-bisphosphate back into F6P, reversing the glycolytic direction to help maintain blood sugar levels.
Gateway to Carbohydrate Interconversion: The enzyme phosphoglucose isomerase (PGI) rapidly interconverts F6P and D-glucose-6-phosphate (G6P) in a reversible reaction. This allows the cell to easily shift glucose between storage (glycogen), breakdown (glycolysis), or antioxidant production pathways based on its current energy state.
- Feeder for the Pentose Phosphate Pathway (PPP): In its reverse direction, F6P acts as a critical entry point for non-oxidative PPP reactions. Transketolase and transaldolase enzymes utilize F6P to produce ribose-5-phosphate (needed for DNA/RNA synthesis) and erythrose-4-phosphate (needed for aromatic amino acid synthesis).
- Precursor for Hexosamine Biosynthesis: F6P is converted into glucosamine-6-phosphate by the enzyme GFAT. This initializes the hexosamine pathway, which yields UDP-GlcNAc—a crucial building block for protein glycosylation, cell wall components, and cellular structural signaling.

Basic Info

Product Name:

Fructose 6-phosphate

Other Name:

D-Fructose,6-(dihydrogen phosphate);Fructose,6-(dihydrogen phosphate),D-;Fructose 6-(dihydrogen phosphate);Fructose 6-phosphate;D-Fructose 6-phosphate

CAS No.:

643-13-0

Molecular Formula:

C6H13O9P

InChIKeys:

InChIKey=GSXOAOHZAIYLCY-HSUXUTPPSA-N

Molecular Weight:

260.13600

Exact Mass:

260.14

EC Number:

211-395-6

UNII:

2012QM764Y

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

166.72000

Density:

1.936g/cm3

Boiling Point:

591.6ºC at 760 mmHg

Flash Point:

311.6ºC

Refractive Index:

1.622

Water Solubility:

911 mg/mL

Collision Cross Section:

154.2 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|156.44 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|148.02 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|150 Å² [M+Na]+ [CCS Type: TW, Method: calibrated with polyalanine]|154.4 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|144.1 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|154.9 Å² [M+Na-2H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]

See More Fructose 6-phosphate Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Fructose 6-phosphate Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

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D-Fructose-6-phosphate

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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