Oroxylin A

Oroxylin A, also known as arbutin A, is a flavonoid compound extracted from Scutellaria baicalensis. Its molecular formula is C16H12O5, CAS number is 480-11-5, and molecular weight is 284.263. Density 1.4 ± 0.1 g/cm ³, boiling point 540.9 ± 50.0 ° C, melting point 195-197 ° C, flash point 207.4 ± 23.6 ° C.
Qiancen Paper Protein A has pharmacological activities such as anti-cancer, anti-inflammatory, neuroprotective, and anticoagulant. In vitro and animal experiments have shown that it can inhibit the proliferation of cervical cancer HeLa cells by binding to SHCBP1 protein and regulating signaling pathways such as TNF and HIF-1 [1-2]. This compound needs to be stored at 2-8 ° C and has acute toxicity through oral administration category 4. Synthesis can be achieved through baicalein methylation or whole cell biosynthesis in Pichia pastoris, with the latter yielding 339.5 mg/L. Upstream and downstream products include baicalein, iodomethane, and kaempferol flavonoids.