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1-Hydroxy-2,3,5-trimethoxyxanthone

Name: 1-Hydroxy-2,3,5-trimethoxyxanthone
Brand: Cuicheng Bio
SKU: pr2606104160
Price: 200000 USD
Availability: InStock

Unit Price:

$200000-250000/G FOB

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CAS No.:

22804-49-5

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

5mg

Price valid (until):

2026-07-11

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
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Description

1-Hydroxy-2,3,5-trimethoxyxanthone (commonly designated in medical research as HM-1) is a naturally occurring polyphenolic compound belonging to the xanthone chemical class. It is primarily isolated from traditional medicinal herbs, most notably the Tibetan plant Halenia elliptica D. Don and the Polygala paniculata plant.

Its biological functions and pharmacological mechanisms focus heavily on cardiovascular health and tissue inflammation:

Vasorelaxant Action (Cardiovascular Function): HM-1 acts as a potent vasodilator. It relaxes coronary arteries through a dual action: an endothelium-dependent pathway that triggers the release of nitric oxide (NO), and an endothelium-independent pathway that blocks calcium ($Ca^{2+}$) influx through L-type voltage-operated calcium channels.
Anti-Inflammatory Profile: It functions as a protective agent against acute, toxin-induced tissue injuries (such as lipopolysaccharide-induced lung damage). It achieves this by suppressing the expression of key inflammatory proteins, specifically inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2).
Inhibition of Bone Resorption: In bone cellular models, HM-1 effectively impedes osteoclast differentiation. This function positions it as a potential lead scaffold for researching therapies targeting bone loss diseases like osteoporosis.

Basic Info

Product Name:

1-hydroxy-2,3,5-trimethoxyxanthene

Other Name:

1-hydroxy-2,3,5-trimethoxyxanthene;1-Hydroxy-2,3,5-trimethoxy-9H-xanthen-9-one;Tovopyrifolin C 3,5-di-O-methyl ether

CAS No.:

22804-49-5

Molecular Formula:

C16H14O6

InChIKeys:

FFVKXGZKJBHJMS-UHFFFAOYSA-N

Molecular Weight:

302.282

Exact Mass:

302.079

Categories:

Xanthones

Characteristics

PSA:

74.2

XLogP3:

3.1

Melting Point:

184-186℃

See More 1-hydroxy-2,3,5-trimethoxyxanthene Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 1-hydroxy-2,3,5-trimethoxyxanthene Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

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1-Hydroxy-2,3,5-trimethoxyxanthone

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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