 Home > Chemical Reagents > Organic Reagents > 4-Methylmorpholine for Sale > 4-Methylmorpholine109-02-4C5H11NO

4-Methylmorpholine109-02-4C5H11NO buy - large image1

4-Methylmorpholine109-02-4C5H11NO buy - image1

4-Methylmorpholine109-02-4C5H11NO buy - image2

4-Methylmorpholine109-02-4C5H11NO buy - image3

4-Methylmorpholine109-02-4C5H11NO buy - image4

4-Methylmorpholine109-02-4C5H11NO

3 Inquiries

Unit Price:

$33-34/MT FOB

Get Latest Price 

CAS No.:

109-02-4

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

上海

Brand:

OORENT

Packaging:

Vial/Bottle/Bag/Carton

Price valid (until):

2026-07-17

Contact Supplier

 Chat Now

Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Product Detail

4-Methylmorpholine Basic information

Product Name:	4-Methylmorpholine
Synonyms:	NMM;N-Methyl morphofine;N-METHYLMORPHOLINE;4-METHYL-1-OXA-4-AZACYCLOHEXANE;4-METHYLMORPHOLINE;AKOS 89985;LUPRAGEN(R) N 105;1-Methylmorpholine
CAS:	109-02-4
MF:	C5H11NO
MW:	101.15
EINECS:	203-640-0
Product Categories:	Building Blocks;Heterocyclic Building Blocks;Morpholines;Protein Sequencing;Protein Structural Analysis;Reagents for Protein Sequencing;MorpholinesEssential Chemicals;Reagent Plus;Routine Reagents;Building Blocks;Chemical Synthesis;proteins;Organic solvents;Indazoles;Heterocyclic Building Blocks;Morpholines/Thiomorpholines;109-02-4;bc0001
Mol File:	109-02-4.mol

4-Methylmorpholine Chemical Properties

Melting point	−66 °C(lit.)
Boiling point	115-116 °C750 mm Hg(lit.)
density	0.92 g/mL at 25 °C(lit.)
vapor density	>1 (vs air)
vapor pressure	18 mm Hg ( 20 °C)
refractive index	n20/D 1.435(lit.)
Fp	75 °F
storage temp.	Store below +30°C.
solubility	Chloroform (Soluble), Ethyl Acetate, Methanol (Slightly)
pka	7.38(at 25℃)
form	Liquid
color	Clear
Specific Gravity	0.920 (20/4℃)
PH	10.6 (50g/l, H2O, 20℃)
explosive limit	2.1%(V)
Water Solubility	>500 g/L (20 ºC)
Merck	14,6277
BRN	102719
Henry's Law Constant	5.0×10⁰ mol/(m³Pa) at 25℃, Du et al. (2017)
Stability:	Volatile
InChI	1S/C5H11NO/c1-6-2-4-7-5-3-6/h2-5H2,1H3
InChIKey	SJRJJKPEHAURKC-UHFFFAOYSA-N
SMILES	CN1CCOCC1
LogP	-0.32 at 25℃
CAS DataBase Reference	109-02-4(CAS DataBase Reference)
NIST Chemistry Reference	Morpholine, 4-methyl-(109-02-4)
EPA Substance Registry System	4-Methylmorpholine (109-02-4)
Absorption	cut-off at 290nm

Safety Information

Hazard Codes	F,C
Risk Statements	11-20/21/22-34-10-22
Safety Statements	16-26-36/37/39-45-25
RIDADR	UN 2535 (4-METHYLMORPHOLINE (N-METHYLMORPHOLINE))
WGK Germany	1
RTECS	QE5775000
F	10-23
Autoignition Temperature	165 °C DIN 51794
TSCA	TSCA listed
HazardClass	3
PackingGroup	II
HS Code	29349990
Storage Class	3 - Flammable liquids
Hazard Classifications	Acute Tox. 4 Oral Eye Dam. 1 Flam. Liq. 2 Skin Corr. 1B
Toxicity	LD50 orally in Rabbit: 1960 mg/kg LD50 dermal Rabbit 1240 mg/kg

MSDS Information

Provider	Language
4-Methyl-1-oxa-4-azacyclohexane	English
ACROS	English
SigmaAldrich	English
ALFA	English

4-Methylmorpholine Usage And Synthesis

Chemical Properties	colorless and transparent liquid. with characteristic odor. soluble in organic solvents, miscible with water and ethanol.
Uses	4-Methylmorpholine is an excellent solvent, emulsifier, corrosion inhibitor, Catalyst in polyurethane foamsextraction solvent, stabilizing agent for chlorinated hydrocarbons, and also can be used as pesticide intermediates. 4-Methylmorpholine is widely used in the synthesis of pesticide compounds such as insecticide, fungicide, plant growth regulator, etc. It is also used in the synthesis of fine chemicals such as surfactant, lubricant coolant, metal antirust agent, fiber treatment agent, etc.
Preparation	4-Methylmorpholine preparation method is to slowly add formaldehyde in morpholine drop by drop, under stirring add formic acid reaction, automatic reflux, and release carbon dioxide. After adding formic acid, heating reflux 4 ~ 5h, cooling and adding sodium hydroxide immediately distillation, collect all the fraction before the boiling point of 99 ℃, and then add sodium hydroxide in the fraction to saturation, cooling the oil layer, drying, fractional distillation, to obtain N-methylmorpholine.
Synthesis Reference(s)	Tetrahedron Letters, 36, p. 4881, 1995 DOI: 10.1016/0040-4039(95)00875-D
General Description	4-Methylmorpholine is a water-white liquid with an ammonia-like odor. Less dense than water and insoluble in water. Flash point 75°F. May be moderately toxic by ingestion, inhalation and skin absorption. Very irritating to skin, eyes, and mucous membranes. Used as a solvent and to make pharmaceuticals.
Air & Water Reactions	Highly flammable. Insoluble in water.
Reactivity Profile	Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health Hazard	May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Fire Hazard	Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Flammability and Explosibility	Flammable
Purification Methods	Dry it by refluxing with BaO or sodium, then fractionally distil it through a helices-packed column. The picrate has m 227o, the thiocyanate salt has m 103o (from butanone). [Hall J Phys Chem 60 63 1956, Beilstein 27 I 203, 27 III/IV 22.]

4-Methylmorpholine Preparation Products And Raw materials

Shop Fluorobenzene462-06-6C6H5F-Detailed Image 2

Basic Info

Product Name:

4-Methylmorpholine

Other Name:

Morpholine,4-methyl-;4-Methylmorpholine;N-Methylmorpholine;1-Methylmorpholine;NMM;NSC 9382;KL 21;Jeffcat NMM;205657-43-8

CAS No.:

109-02-4

Molecular Formula:

C5H11NO

InChIKeys:

InChIKey=SJRJJKPEHAURKC-UHFFFAOYSA-N

Molecular Weight:

101.15

Exact Mass:

101.15

BRN:

102719

EC Number:

203-640-0

UNII:

11P91ANU5X

NSC Number:

9382

UN Number:

2535

DSSTox ID:

DTXSID9029146

HScode:

29349990

Categories:

Organic Reagents

Characteristics

PSA:

12.5

XLogP3:

-0.33

Appearance:

Clear Liquid

Density:

0.91406 g/cm³ @ Temp: 25.00 °C

Melting Point:

146-147 °C

Boiling Point:

116 °C

Flash Point:

75 °F

Refractive Index:

n 20/D 1.435(lit.)

Water Solubility:

>500 g/L (20 ºC)Highly flammable. Insoluble in water.

Storage Conditions:

Store at RT.

Vapor Pressure:

18 mm Hg ( 20 °C)

Vapor Density:

>1 (vs air)

Toxicity:

Oral-Rat LD50: 1960 mg/kg; Oral-Mouse LD50: 1970 mg/kg

Flammability characteristics:

Inflammable in case of open flame, high temperature, oxidant; burning produces toxic nitrogen oxide fumes

Explosive limit:

2.1%(V)

Air and Water Reactions:

Highly flammable. Insoluble in water.

Reactive Group:

Amines, Phosphines, and Pyridines

Reactivity Alerts:

Highly Flammable

Reactivity Profile:

Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

See More 4-Methylmorpholine Properties 

Hazard Identification

Classification of the substance or mixture

Flammable liquids, Category 2

Acute toxicity - Category 4, Oral

Skin corrosion, Sub-category 1B

Serious eye damage, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H225 Highly flammable liquid and vapour H302 Harmful if swallowed H314 Causes severe skin burns and eye damage
Prevention	P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment. P242 Use non-sparking tools. P243 Take action to prevent static discharges. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response	P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower]. P370+P378 In case of fire: Use ... to extinguish. P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 Wash contaminated clothing before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P316 Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help.
Storage	P403+P235 Store in a well-ventilated place. Keep cool. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 4-Methylmorpholine Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
Russia	N-Methylmorpholine	100 KG	Mar 17, 2026
Uzbekistan	n-methylmotpholine	1 TON	Aug 5, 2025
India	N-Methylmorpholine	1 20' Fcl	Oct 17, 2024

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Supplier Name	Details
N-Methyl morphofine	/	Shandong zhishang chemical Co.,Ltd	Inquiry
4-Methylmorpholine 99.0% Colourless clear liquid Yuanjinchem	Industrial Grade/99.0	Zhejiang Yuanjin Chemical Co., Ltd.	Inquiry
N-Methylmorpholine 99% see COA kanbei	/99	Henan Lihao Chem Plant Limited	Inquiry
High Quality 99% Purity of 4-Methylmorpholine CAS NO 109-02-4 ISO 9001:2005 REACH Verified Producer	Industrial Grade/99	Shaanxi Dideu Medichem Co. Ltd	Inquiry
N-Methylmorpholine	/0.99	shanghai jinghui industrial co.ltd	Inquiry

Hot Related Products



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.