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Isopropyl chloroformate108-23-6

Unit Price:

$33-34/MT FOB

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CAS No.:

108-23-6

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

上海

Brand:

OORENT

Packaging:

Vial/Bottle/Bag/Carton

Price valid (until):

2026-07-17

Company Type:
Trader
Location:
China
Qualification:
Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

  • Product Description

  • Seller Information

  • Description

    Product Detail


    Isopropyl chloroformate Basic information
    Product Name: Isopropyl chloroformate
    Synonyms: chlorocarbonicacidisopropylester;chloro-formicaciisopropylester;isopropylchloroformatesolution;isopropylchloromethanoate;isopropylesterkyselinychlormravenci;ISOPROPYL CHLOROCARBONATE;ISOPROPYL CHLOROFORMATE;IPCF
    CAS: 108-23-6
    MF: C4H7ClO2
    MW: 122.55
    EINECS: 203-563-2
    Product Categories: Indolines ,Indoles ,Indazoles;Acid Halides;CHLOROFORMATES;Carbonyl Compounds;Organic Building Blocks;Agrochemicals;A
    Mol File: 108-23-6.mol
    Shop Isopropyl chloroformate108-23-6-Detailed Image 1

    Isopropyl chloroformate Chemical Properties
    Boiling point  105 °C
    density  0.892 g/mL at 25 °C
    vapor pressure  27.998hPa at 20℃
    refractive index  n20/D 1.485(lit.)
    Fp  43 °F
    storage temp.  2-8°C
    solubility  Chloroform (Sparingly), Dichloromethane (Soluble), Ethyl Acetate (Slightly), Tol
    form  liquid
    BRN  506416
    Henry's Law Constant 2.4×10-3 mol/(m3Pa) at 25℃, HSDB (2015)
    Stability: Moisture Sensitive
    InChI InChI=1S/C4H7ClO2/c1-3(2)7-4(5)6/h3H,1-2H3
    InChIKey IVRIRQXJSNCSPQ-UHFFFAOYSA-N
    SMILES C(Cl)(OC(C)C)=O
    CAS DataBase Reference 108-23-6(CAS DataBase Reference)
    EPA Substance Registry System Isopropyl chloroformate (108-23-6)

    Safety Information
    Hazard Codes  F,C,T+
    Risk Statements  11-34-48/20-63-65-67-43-26
    Safety Statements  26-36/37/39-45-62-28-16
    RIDADR  UN 2407
    WGK Germany  2
    RTECS  LQ6475000
    10-19
    TSCA  TSCA listed
    HazardClass  6.1
    PackingGroup  I
    HS Code  29159000
    Storage Class 3 - Flammable liquids
    Hazard Classifications Acute Tox. 1 Inhalation
    Aquatic Chronic 3
    Asp. Tox. 1
    Eye Dam. 1
    Flam. Liq. 2
    Repr. 2
    Skin Corr. 1B
    Skin Sens. 1
    STOT RE 2
    STOT SE 3
    Hazardous Substances Data 108-23-6(Hazardous Substances Data)
    MSDS Information
    Provider Language
    Carbonochloridic acid 1-methylethyl ester English
    SigmaAldrich English

    Isopropyl chloroformate Usage And Synthesis
    Chemical Properties Isopropyl chloroformate is a colorless liquid with corrosive properties and a pungent odor. generally present as 1.0 mol/L toluene solution of isopropyl chloroformate. It is a highly flammable chemical. Isopropyl chloroformate decomposes when heated, producing toxic and corrosive fumes, including hydrogen chloride and phosgene. The chemical reacts with water to produce alcohol and hydrogen chloride. Hydrolysis would yield chloroformic acid, which is considered a strong acid.
    Uses Chemical intermediate for free-radical polymerization initiators, organic synthesis.
    Uses Isopropyl chloroform was used in the preparation of isopropyl cyclohexane via alkylation of cyclohexene. It was also used in the preparation of 10-isopropyloctadecanoic acid via reaction with oleic acid in the presence of ethylaluminum sesquichloride
    Production Methods Prepared by the reaction of liquid anhydrous isopropyl alcohol with molar excess of dry, chlorine-free phosgene at low temperature.
    General Description A clear colorless volatile liquid with a pungent irritating odor. About the same density as water and insoluble in water. Floats on water Flash point 75°F. Very irritating to skin and eyes and very toxic by inhalation, ingestion and skin absorption. Used to make other chemicals.
    Air & Water Reactions Highly flammable. Gives off HCl fumes in moist air. Insoluble in water. Decomposes slowly in water forming isopropyl alcohol, HCl, and CO2.
    Reactivity Profile Isopropyl chloroformate is water reactive. A sample stored in a refrigerator exploded [Wischmeyer 1973]. Attacks many metals especially in humid atmosphere [Handling Chemicals Safely, 1980. p. 476]. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
    Hazard Toxic by inhalation.
    Health Hazard Acute: highly toxic by inhalation, ingestion and skin absorption. Delayed: can produce delayed pulmonary edema (2-24 hours after exposure) similar to that produced by phosgene. Inhalation of material may cause death or permanent injury.
    Fire Hazard Extremely dangerous; Isopropyl chloroformate has exploded while stored in refrigerator. Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Like other chlorides, when heated to decomposition or on contact with acids or acrid fumes, they evolve highly toxic chloride fumes. Reacts violently with phosgene. Unstable, avoid phosgene

    Shop 3-Chloro-1-propene107-05-1-Detailed Image 2 Shop 3-Chloro-1-propene107-05-1-Detailed Image 3 Shop 3-Chloro-1-propene107-05-1-Detailed Image 4 Shop 3-Chloro-1-propene107-05-1-Detailed Image 5 Shop 3-Chloro-1-propene107-05-1-Detailed Image 6 Shop 3-Chloro-1-propene107-05-1-Detailed Image 7


    Basic Info
    Product Name:

    Isopropyl chloroformate

    Other Name:

    Carbonochloridic acid,1-methylethyl ester;Formic acid,chloro-,isopropyl ester;Isopropyl chlorocarbonate;Isopropyl chlorcarbonate;Isopropyl chloroformate;Chloroformic acid isopropyl ester;2-Propyl chloroformate;1-Methylethyl chloroformate;Isopropoxycarbonyl chloride;Isopropyl carbonochloridate;94274-22-3

    CAS No.:

    108-23-6

    Molecular Formula:

    C4H7ClO2

    InChIKeys:

    InChIKey=IVRIRQXJSNCSPQ-UHFFFAOYSA-N

    Molecular Weight:

    122.55

    Exact Mass:

    122.55

    EC Number:

    203-563-2

    UNII:

    8LG1G18VXR

    ICSC Number:

    0287

    UN Number:

    2407

    DSSTox ID:

    DTXSID7026786

    Color/Form:

    COLORLESS LIQ

    HScode:

    29159000

    Characteristics
    PSA:

    26.3

    XLogP3:

    1.79

    Appearance:

    Isopropyl chloroformate appears as a clear colorless volatile liquid with a pungent irritating odor. About the same density as water and insoluble in water. Floats on water Very irritating to skin and eyes and very toxic by inhalation, ingestion and skin absorption. Used to make other chemicals.

    Density:

    1.08 g/cm3

    Melting Point:

    -81ºC

    Boiling Point:

    104.6 °C @ Press: 761 Torr

    Flash Point:

    43 °F

    Refractive Index:

    1.409

    Water Solubility:

    Solubility in water: slow reaction

    Storage Conditions:

    2-8°C

    Vapor Pressure:

    Vapour pressure, kPa at 20°C: 3

    Vapor Density:

    Relative vapour density (air = 1): 4.2

    Toxicity:

    Oral-Rat  LD50:1070 mg/kg; Oral-Mouse LD50: 178 mg/kg

    Flammability characteristics:

    Open flame is flammable; high heat emits toxic chloride gas

    Explosive limit:

    vol% in air: 45

    Odor:

    Pungent

    Experimental Properties:

    5.00 MG/CU M= 1 PPM|Flash point: 27.8 °C (Tag open cup), 23.3 °C (Tag closed cup)|Flash point = 14 °C; Autoignition temp = 535 °C|Chloroformates are reactive intermediates that combine acid chloride, and ester functions. They undergo many reactions of acid chlorides, however, the rates are usually slower. Reactions of chloroformates, like other acid chlorides, proceed faster with better yields when alkali hydroxides or tertiary amines are present to react with the HCl as it forms. /Chloroformates/

    Air and Water Reactions:

    Highly flammable. Gives off HCl fumes in moist air. Insoluble in water. Decomposes slowly in water forming isopropyl alcohol, HCl, and CO2.

    Reactive Group:

    Acyl Halides, Sulfonyl Halides, and Chloroformates

    Reactivity Alerts:

    Highly Flammable

    Reactivity Profile:

    ISOPROPYL CHLOROFORMATE is water reactive. A sample stored in a refrigerator exploded [Wischmeyer 1973]. Attacks many metals especially in humid atmosphere [Handling Chemicals Safely, 1980. p. 476]. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

    Autoignition Temperature:

    >500 °C

    Physical Dangers:

    The vapour is heavier than air and may travel along the ground; distant ignition possible.

    Hazard Identification

    Classification of the substance or mixture

    Flammable liquids, Category 2

    Acute toxicity - Category 4, Oral

    Skin corrosion, Sub-category 1B

    Acute toxicity - Category 2, Inhalation

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H225 Highly flammable liquid and vapour

    H302 Harmful if swallowed

    H314 Causes severe skin burns and eye damage

    H330 Fatal if inhaled

    Precautionary statement(s)
    Prevention

    P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

    P233 Keep container tightly closed.

    P240 Ground and bond container and receiving equipment.

    P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.

    P242 Use non-sparking tools.

    P243 Take action to prevent static discharges.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P284 [In case of inadequate ventilation] wear respiratory protection.

    Response

    P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].

    P370+P378 In case of fire: Use ... to extinguish.

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

    P363 Wash contaminated clothing before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P316 Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P320 Specific treatment is urgent (see ... on this label).

    Storage

    P403+P235 Store in a well-ventilated place. Keep cool.

    P405 Store locked up.

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Fireproof. Separated from strong oxidants and food and feedstuffs. Dry. Well closed.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    pharmaceutical intermediates,peptides,electronic chemicals

    Location:

    Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

    Payment Terms:

    100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    51-100

    Year of Establishment:

    2024

    A reliable supplier is like insurance.

    We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals,food additives, and other fine chemical products.
    Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

    Website: orientchem.cc
    Email: scarlett@orientchem.cc
    WhatsApp: +86 17753254221

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