Healthy aging Antioxidant ingredients S-Acetyl L-Glutathione SGSH S-A-GSH

What is S-Acetyl-L-glutathione?

S-acetyl L-glutathione is an acetylated modified reduced L-glutathione with superior stability and cell membrane penetration compared to ordinary glutathione. It resists degradation by gastric acid and significantly enhances oral bioavailability. Widely used in skin whitening, anti-aging, liver detoxification, dietary supplementation, and other fields, it is currently the highly favored upgraded form of glutathione in premium beauty and health care products

Product name：S-Acetyl-L-glutathione

CAS No.：3054-47-5

Formula ：C12H19N3O7S

Formula Weight：349.36

Purity: >98%

Package size： 25KG/bag ， 25KG/drum

1. S-acetyl-L-glutathione protects the molecular structure of glutathione by acetylating it, enabling it to withstand damage from gastric acid and digestive enzymes. This significantly enhances oral absorption efficiency and facilitates penetration through cell membranes. Upon entering cells, the acetyl group is removed, rapidly converting it into biologically active reduced glutathione. It directly functions as a key antioxidant to eliminate free radicals in the body, inhibit tyrosinase activity, reduce melanin synthesis and deposition, maintain cellular redox balance, and protect cell membrane integrity. These mechanisms achieve core physiological effects such as antioxidant action, skin whitening, pigmentation reduction, and cellular repair .

• 1,Antioxidant: neutralizes free radicals, protects cells from oxidative damage
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• 2,Detoxification and liver protection: Promote the elimination of toxins, reduce the damage of drugs, alcohol, etc. to the liver.
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• 3,Immune regulation: Enhance immune cells and improve the body's ability to resist infections. Reduce the level of chronic inflammation.
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• 4,Skin whitening and anti-aging: inhibits tyrosinase activity, reduces melanin production, promotes collagen synthesis
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• 5,Neurological protection: crossing the blood-brain barrier to reduce oxidative stress in the brain.

We get L-glutathione through enzymatic synthesis, and then perform directed acylation to obtain high-purity, low impurity S-acetyl-L-glutathione. Our S-acetyl-L-glutathione has a purity of over 98%. The following is our flowchart.

S-Acetyl-L-Glutathione is a synthetic ingredient that is more stable and easily absorbed than regular L-glutathione. Vegetables such as asparagus, avocado, spinach, broccoli, kale, meat such as beef, fish, pork liver, eggs, fruit such as kiwi, and grapes contain L-glutathione.

Application scenarios of S-Acetyl-L-Glutathione

• 1,Dietary supplements: brighten skin, anti glycation, antioxidant, protect liver
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• 2,Skincare products: brighten skin tone, lighten blemishes, reduce inflammation and pigmentation
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• 3,Pet nutrition:liver protection, hair beautification & brightening, antioxidant
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• 4,Functional food and beverage: whitening, antioxidant detoxification

What products can be used in combination with ?

S-Acetyl-L-Glutathione has the effects of whitening, anti-aging, detoxification, and enhancing immunity. When used in combination with specific ingredients, it can produce synergistic effects

• Whitening and brightening: Glutathione+Niacinamide+Vitamin C
• Detoxification combination: SAG+Silymarin +N-acetylcysteine (NAC)
• Anti aging & antioxidant: SAG+ ALA +coenzyme Q10+resveratrol+vitamin E

How to Select S-Acetyl-L-Glutathione Raw Materials?

Choose the left-handed L configuration, with a purity of above 98% , avoiding racemic mixtures and non-specific acetylation by-products; Priority should be given to products using biocatalytic processes, which have low impurities and minimal solvent residue. The factory also needs to provide a formal COA.