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Home > Pharmaceutical Intermediates > Blood Glucose Regulators > Cyclohexanone for Sale > Cyclohexanone | Pharmaceutical Grade | 99.99% Purity | 10mg 20mg 30mg Vials | Lyophilized Powder | CAS 108-94-1
Cyclohexanone | Pharmaceutical Grade | 99.99% Purity | 10mg 20mg 30mg Vials | Lyophilized Powder | CAS  108-94-1 buy - large image1
Cyclohexanone | Pharmaceutical Grade | 99.99% Purity | 10mg 20mg 30mg Vials | Lyophilized Powder | CAS  108-94-1 buy - image1
Cyclohexanone | Pharmaceutical Grade | 99.99% Purity | 10mg 20mg 30mg Vials | Lyophilized Powder | CAS  108-94-1 buy - image2
Cyclohexanone | Pharmaceutical Grade | 99.99% Purity | 10mg 20mg 30mg Vials | Lyophilized Powder | CAS  108-94-1 buy - image3
Cyclohexanone | Pharmaceutical Grade | 99.99% Purity | 10mg 20mg 30mg Vials | Lyophilized Powder | CAS  108-94-1 buy - image4
Cyclohexanone | Pharmaceutical Grade | 99.99% Purity | 10mg 20mg 30mg Vials | Lyophilized Powder | CAS  108-94-1 buy - image5
Cyclohexanone | Pharmaceutical Grade | 99.99% Purity | 10mg 20mg 30mg Vials | Lyophilized Powder | CAS  108-94-1 buy - image6

Cyclohexanone | Pharmaceutical Grade | 99.99% Purity | 10mg 20mg 30mg Vials | Lyophilized Powder | CAS 108-94-1

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CAS No.:

108-94-1

Grade:

Pharmaceutical Grade

Content:

99.99%

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  • Description
    Cyclohexanone Basic information
    Chemical propertiesApplicationUsesProduction method
    Product Name: Cyclohexanone
    Synonyms: Anon;caswellno270;Cicloesanone;Cykloheksanon;Cyclohexanone Manufacturer;CYCLOHEXANONE, REAGENT (ACS)CYCLOHEXANONE, REAGENT (ACS)CYCLOHEXANONE, REAGENT (ACS);AKOS BBS-00004296;PIMELIC KETONE
    CAS: 108-94-1
    MF: C6H10O
    MW: 98.14
    EINECS: 203-631-1
    Product Categories: Alphabetical Listings;C-D;Alpha Sort;C;CAlphabetic;Flavors and Fragrances;CO - CZ;Volatiles/ Semivolatiles;Analytical Reagents for General Use;C-D, Puriss p.a.;Puriss p.a.;ACS GradeCarbonyl Compounds;C3 to C6;Essential Chemicals;Intermediates of Dyes and Pigments;Ketones;Routine Reagents;Reagent Plus;Analytical/Chromatography;Auxiliaries for ISE;Ion Sensor Materials;Halogenated Heterocycles ,Indolines ,Indoles ,Indazoles;pharmaceutical intermediate;1;108-94-1
    Mol File: 108-94-1.mol
    Shop Cyclohexanone108-94-1C6H10O-Detailed Image 1

    Cyclohexanone Chemical Properties
    Melting point  -47 °C (lit.)
    Boiling point  155 °C (lit.)
    density  0.947 g/mL at 25 °C (lit.)
    vapor density  3.4 (vs air)
    vapor pressure  3.4 mm Hg ( 20 °C)
    refractive index  n20/D 1.450(lit.)
    FEMA  3909 | CYCLOHEXANONE
    Fp  116 °F
    storage temp.  Store at +5°C to +30°C.
    solubility  90g/l
    pka 17(at 25℃)
    form  Liquid
    color  APHA: ≤10
    PH 7 (70g/l, H2O, 20℃)
    Odor Like peppermint and acetone.
    Relative polarity 0.281
    Odor Type minty
    biological source synthetic
    explosive limit 1.1%, 100°F
    Water Solubility  150 g/L (10 ºC)
    Thermal Conductivity 0.144 W/(m·K) at 25 ℃
    Merck  14,2726
    JECFA Number 1100
    BRN  385735
    Henry's Law Constant 1.2 x 10-5 atmm3/mol at 25 °C (Hawthorne et al., 1985) 6.92 x 10-5 atmm3/mol at 60.00 °C, 10.7 at 70.00 °C, 16.4 at 80.00 °C (headspace-GC, Hovorka et al., 2002)
    Exposure limits PC-TWA: 50 mg/m3
    Dielectric constant 18.2(20℃)
    Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
    Major Application flavors and fragrances
    Cosmetics Ingredients Functions PERFUMING
    SOLVENT
    InChI 1S/C6H10O/c7-6-4-2-1-3-5-6/h1-5H2
    InChIKey JHIVVAPYMSGYDF-UHFFFAOYSA-N
    SMILES O=C1CCCCC1
    LogP 0.86 at 25℃
    Surface tension 33.74mN/m at 298.15K
    CAS DataBase Reference 108-94-1(CAS DataBase Reference)
    IARC 3 (Vol. 47, 71) 1999
    NIST Chemistry Reference Cyclohexanone(108-94-1)
    EPA Substance Registry System Cyclohexanone (108-94-1)

    Safety Information
    Hazard Codes  Xn
    Risk Statements  10-20-41-38-20/21/22
    Safety Statements  25-36/37/39-26
    RIDADR  UN 1915
    OEB A
    OEL TWA: 25 ppm (100 mg/m3) [skin]
    WGK Germany  1
    RTECS  GW1050000
    Autoignition Temperature 788 °F
    TSCA  TSCA listed
    HS Code  2914 22 00
    HazardClass  3
    PackingGroup  III
    Storage Class 3 - Flammable liquids
    Hazard Classifications Acute Tox. 4 Dermal
    Acute Tox. 4 Inhalation
    Acute Tox. 4 Oral
    Eye Dam. 1
    Flam. Liq. 3
    Skin Irrit. 2
    STOT SE 3
    Hazardous Substances Data 108-94-1(Hazardous Substances Data)
    Toxicity LD50 orally in rats: 1.62 ml/kg (Smyth)
    IDLH 700 ppm
    MSDS Information
    Provider Language
    SigmaAldrich English
    ACROS English
    ALFA English

    Cyclohexanone Usage And Synthesis
    Chemical properties Cyclohexanone is a colorless, clear liquid with soil smell; its impure product appears as light yellow color. It is miscible with several other solvents. easily soluble in ethanol and ether. The lower exposure limit is 1.1% and the upper exposure limit is 9.4%. Cyclohexanone may be incompatible with oxidizers and nitric acid.
    Cyclohexanone is a primarily used in industry, up to 96%, as a chemical intermediate in the production of nylons 6 and 66. Oxidation or conversion of cyclohexanone yields adipic acid and caprolactam, two of the immediate precursors to the respective nylons. Cyclohexanone can also be used as a solvent in a variety of products, including paints, lacquers, and resins. It has not been found to occur in natural processes.
    Application Cyclohexanone is mostly captively consumed, either isolated or as a mixture, in the production of nylon intermediates (adipic acid and Caprolactam). Around 4% is consumed in markets other than nylon, such as solvents for paints, dyes and pesticides. Cyclohexanone is also used in the manufacture of pharmaceuticals, films, soaps and coatings.
    Fibrant is one of the largest producers of Cyclohexanone, a raw material used in the production of Caprolactam.
    Uses Cyclohexanone is an important chemical raw material, being the major intermediates of making nylon, caprolactam and adipic acid. It is also an important industrial solvent, for example, for paints, especially for those containing nitrocellulose, vinyl chloride polymers and their copolymers or methacrylate polymer paints. Used as an excellent solvent for pesticides such as organophosphate insecticide. It is used as a solvent for dyes, viscous solvents for piston aviation lubricants, solvents for greases, waxes and rubbers. Also used as leveling agent for dyeing and fading silk; degreasing agents for polishing metal; wood coloring paint; also used for cyclohexanone stripping, decontamination and spot removal. Cyclohexanone and cyanoacetic acid can have condensation reaction to generate cyclohexylidene acetic acid, and then followed by elimination and decarboxylation to get cyclohexene acetonitrile, and finally giving cyclohexene ethylamine by hydrogenation [3399-73-3]. Cyclohexene ethylamine is a intermediate for some drugs.
    Production method In the 1940s, the industrial production of cyclohexanone mainly applied hydrogenation of phenol to generate cyclohexanol, followed by dehydrogenation to give cyclohexanone. In the 1960s, with the development of petrochemical industry, the cyclohexane oxidation production method gradually dominated. In 1967, the one step method of phenol hydrogenation, developed by the Netherlands National Mining Company (DSM) was industrialized. This method has short production process, good product quality and high yield, but the raw materials of phenol and catalyst are expensive, so the majority of the industry still adopts the cyclohexane oxidation method.
    1. Phenol method takes nickel as a catalyst; first apply hydrogenation of phenol to give cyclohexanol, followed by dehydrogenation to give cyclohexanone using zinc as the catalyst for zinc.
    2. Cyclohexane oxidation method uses cyclohexane as the raw material; first apply non-catalyst condition; use oxygen-rich air for oxidation to give cyclohexyl hydroperoxide, followed by decomposition into the mixture of cyclohexanol, cyclohexanone, alcohol and ketone in the presence of tert-butyl chromate catalyst; further apply a series of distillation refinement to get qualified products. Raw material consumption quota: cyclohexane (99.6%) 1040kg / t.
    3. Benzene hydrogenation oxidation method; benzene subjects to hydrogenation (with hydrogen) at 120-180 ℃ in the presence of nickel catalyst to generate cyclohexane; cyclohexane has oxidation reaction with air at 150-160 ℃, 0.908MPa to obtain the mixture of cyclohexanol and cyclohexanone; separate them to obtain the cyclohexanone product. Cyclohexanol is dehydrogenated at 350-400 ° C in the presence of a zinc-calcium catalyst to produce cyclohexanone. Raw material consumption quotas: benzene (99.5%) 1144kg / t, hydrogen (97.0%) 1108kg / t, caustic soda (42.0%) 230kg / t.
    Description Cyclohexanone, a colorless liquid is a cyclic ketone. It is an important building block for the synthesis of a variety of organic compounds. Majority of the cyclohexanone synthesized is utilized as an intermediate in the synthesis of nylon.
    Used as a polyvinyl chloride (PVC) solvent, cyclohexanone caused contact dermatitis in a woman manufacturing PVC fluidotherapy bags. Cyclohexanone probably does not cross react with cyclohexanone resin. A cyclohexanone-derived resin used in paints and varnishes caused contact dermatitis in painters.Shop Cyclohexanone108-94-1C6H10O-Detailed Image 2
    Chemical Properties Cyclohexanone is a water-white to slightly yellow liquid with a peppermint-like or acetone-like odor. The Odor Threshold is 0.12 0.24 ppm in air.
    Physical properties Clear, colorless to pale yellow, oily liquid with a peppermint-like odor. Experimentally determined detection and recognition odor threshold concentrations were identical: 480 μg/m3 (120 ppmv) (Hellman and Small, 1974).
    Occurrence Reported present in Cistus labdaniferus.
    Uses Industrial solvent for cellulose acetate resins, vinyl resins, rubber, and waxes; solventsealer for polyvinyl chloride; in printing industry; coating solvent in audio and videotape production
    Uses Cyclohexanone is used as an industrial solvent and paint remover. It acts as a precursor to nylon 6,6 and nylon 6 and cyclohexanone oxime, which gives caprolactam on rearrangement. Further, it is used as a chemical reaction medium, adhesives, sealants and agricultural products.
    Uses Cyclohexanone is used in the productionof adipic acid for making nylon; in thepreparation of cyclohexanone resins; and asa solvent for nitrocellulose, cellulose acetate,resins, fats, waxes, shellac, rubber, and DDT..
    Definition ChEBI: A cyclic ketone that consists of cyclohexane bearing a single oxo substituent.
    Synthesis Reference(s) Canadian Journal of Chemistry, 62, p. 1031, 1984 DOI: 10.1139/v84-171
    Tetrahedron Letters, 25, p. 3309, 1984 DOI: 10.1016/S0040-4039(01)81371-X
    General Description A colorless to pale yellow liquid with a pleasant odor. Less dense than water . Flash point 111°F. Vapors heavier than air. Used to make nylon, as a chemical reaction medium, and as a solvent.
    Air & Water Reactions Flammable. Soluble in water.
    Reactivity Profile Cyclohexanone forms an explosive peroxide with H2O2, and reacts vigorously with oxidizing materials (nitric acid).
    Health Hazard Inhalation of vapors from hot material can cause narcosis. The liquid may cause dermatitis.
    Health Hazard The toxicity of cyclohexanone in test specieswas found to be low to moderate. Exposureto its vapors can produce irritation in the eyesand throat. Splashing into the eyes can damagethe cornea. Throat irritation in humansmay occur from 3–5 minute exposure to a50-ppm concentration in air. The symptomsof chronic toxicity in animals from its inhalationwere liver and kidney damage, as wellas weight loss. However, its acute toxicitywas low below 3000 ppm. The symptomsin guinea pigs were lacrimation, salivation,lowering of heart rate, and narcosis. Exposureto 4000 ppm for 4–6 hours was lethalto rats and guinea pigs.
    The oral toxicity of this compound waslow. Ingestion may cause narcosis and depressionof the central nervous system. It canbe absorbed through the skin.
    LD50 value, dermal (rabbits): 1000 mg/kg
    LD50 value, intraperitoneal (rats): 1130 mg/kg.
    Fire Hazard HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
    Flammability and Explosibility Flammable
    Chemical Reactivity Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
    Contact allergens Used as a polyvinyl chloride solvent, cyclohexanone caused contact dermatitis in a woman manufacturing PVC fluidotherapy bags. Cyclohexanone probably does not cross-react with cyclohexanone resin. A cyclohexanone-derived resin used in paints and varnishes caused contact dermatitis in painters
    Safety Profile Suspected carcinogen. Moderately toxic by ingestion, inhalation, subcutaneous, intravenous, and intraperitoneal routes. A skin and severe eye irritant. Human systemic effects by inhalation: changes in the sense of smell, conjunctiva irritation, and unspecified respiratory system changes. Human irritant by inhalation. Mdd narcotic properties have also been ascribed to it. Human mutation data reported. Experimental reproductive effects. Flammable liquid when exposed to heat or flame; can react vigorously with oxidizing materials. Slight explosion hazard in its vapor form, when exposed to flame.Reaction with hydrogen peroxide + nitric acid forms an explosive peroxide. To fight fire, use alcohol foam, dry chemical, or COa. When heated to decomposition it emits acrid smoke and irritating fumes. See also KETONES and CYCLOHEXANE.
    Synthesis It may be synthesized on a laboratory scale by the oxidation of cyclohexanol.
    Potential Exposure May form explosive mixture with air. Contact with oxidizing agents or nitric acid may cause a violent reaction. Do not use brass, copper, bronze, or lead fittings. Attacks many coatings and plastic materials.
    First aid If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.
    Carcinogenicity IARC considers the animal data for cyclohexanone as inadequate evidence of carcinogenicity and listed cyclohexanone as not classifiable for carcinogenicity (IARC Category 3).
    Environmental fate Biological. In activated sludge inoculum, 96.0% COD removal was achieved. The average rate of biodegradation was 30.0 mg COD/gh (Pitter, 1976).
    Photolytic. Atkinson (1985) reported an estimated photooxidation rate constant of 1.56 x 10-11 cm3/moleculesec for the reaction of cyclohexanone and OH radicals in the atmosphere at 298 K. Chemical/Physical. Cyclohexanone will not hydrolyze because it has no hydrolyzable functional group.
    At an influent concentration of 1,000 mg/L, treatment with GAC resulted in effluent concentration of 332 mg/L. The adsorbability of the carbon used was 134 mg/g carbon (Guisti et al., 1974). Similarly, at influent concentrations of 10, 1.0, 0.1, and 0.01 mg/L, the GAC adsorption capacities were 36, 6.2, 1.1, and 0.19 mg/g, respectively (Dobbs and Cohen, 1980).
    storage Color Code—Red: Flammability Hazard: Store ina flammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.Prior to working with Cyclohexanone you should be trainedon its proper handling and storage. Before entering confinedspace where this chemical may be present, check to make sure that an explosive concentration does not exist.Cyclohexanone must be stored to avoid contact with oxidizers (such as perchlorates, peroxides, chlorates, nitrates, andpermanganates), since violent reactions occur. Store intightly closed containers in a cool well-ventilated area awayfrom heat, sparks, and flames. Metal containers involvingthe transfer of this chemical should be grounded andbonded. Where possible, automatically pump liquid fromdrums or other storage containers to process containers.Drums must be equipped with self-closing valves, pressurevacuum bungs, and flame arresters. Use only nonsparkingtools and equipment, especially when opening and closingcontainers of this chemical. Sources of ignition, such assmoking and open flames, are prohibited where this chemical is used, handled, or stored in a manner that could createa potential fire or explosion hazard. Wherever this chemicalis used, handled, manufactured, or stored, use explosionproof electrical equipment and fittings.Cyclohexanone requires a “FLAMMABLELIQUID” label. It falls in Hazard Class 3 and PackingGroup II
    Shipping UN1915 Cyclohexanone, Hazard Class: 3; Labels: 3-Flammable liquid.
    Purification Methods Dry cyclohexanone with MgSO4,CaSO4, Na2SO4 or Linde type 13X molecular sieves, then distil it. Cyclohexanol and other oxidisable impurities can be removed by treatment with chromic acid or dilute KMnO4. More thorough purification is possible by conversion to the bisulfite addition compound, or the semicarbazone, followed by decomposition with Na2CO3 and steam distillation. [For example, equal weights of the bisulfite adduct (crystallised from water) and Na2CO3 are dissolved in hot water and, after steam distillation, the distillate is saturated with NaCl and extracted with Et2O which is then dried (anhydrous MgSO4 or Na2SO4), filtered and the solvent evaporated prior to further distillation.] FLAMMABLE [Beilstein 7 III 14, 7 IV 15.]
    Incompatibilities May form explosive mixture with air. Contact with oxidizing agents or nitric acid may cause a violent reaction. Do not use brass, copper, bronze, or lead fittings. Attacks many coatings and plastic materials.
    Toxics Screening Level The initial threshold screening level (ITSL) for cyclohexanone has been changed from 1000 μg/m3 (8-hour averaging time) to 800 μg/m3 (8-hour averaging time).
    Waste Disposal Dissolve or mix the material with a combustible solvent and burn in a chemical incinera- tor equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

    Cyclohexanone Preparation Products And Raw materials
    Raw materials Sodium hydroxide-->Benzene-->Hydrogen peroxide-->Hydrogen-->Water-->Cyclohexane-->PETROLEUM ETHER-->Cyclohexanol-->heavy benzol-->2-Hexanone-->tert-Butyl chromate
    Preparation Products Tramadol hydrochloride-->Ondansetron-->Venlafaxine hydrochloride-->(1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine-->Deflazacort-->1-Ethynyl-1-cyclohexanol-->Venlafaxine-->1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE-->(R)-2-AMINO-6-METHYLHEPTANE, 98% E.E., 95-->Ethyl 2-oxocyclohexanecarboxylate-->Carbosulfan-->3-AMINO-5,6,7,8-TETRAHYDRO-3H-BENZO[4,5]THIENO[2,3-D]PYRIMIDIN-4-ONE-->Clethodim-->3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER-->2-ETHYLCYCLOHEXANONE-->Pramipexole-->2-(HYDROXYMETHYL)CYCLOHEXANONE-->2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBONITRILE-->N-Methylcyclohexylamine-->5,6,7,8-TETRAHYDRO-3H-BENZO[4,5]THIENO[2,3-D]-PYRIMIDIN-4-ONE-->Acid Orange 33-->Methoxydienone-->1-(aminomethyl)cyclohexan-1-ol-->2-(4-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine-->ETHYL 2-AMINO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE-->Cycloheptanone-->1,2-Cyclohexanedione-->2-(1-CYCLOHEXENYL)CYCLOHEXANONE-->ε-Caprolactone-->1-Hydroperoxycyclohexyl-1-hydroxycyclohexyl peroxide-->1-NITROMETHYLCYCLOHEXANOL-->Cyclohexanone peroxide-->Polyurethane varnish-->adhesive No.1 for shrink packaging-->(1-HYDROXY-CYCLOHEXYL)-ACETONITRILE-->N,N-Dimethylcyclohexylamine-->1-AMINOMETHYL-1-CYCLOHEXANOL HYDROCHLORIDE-->1-(1-PIPERIDINO)CYCLOHEXENE-->Porcelain-like coating-->2-Chlorocyclohexanone
    Shop Cyclohexanone | Pharmaceutical Grade | 99.99% Purity | 10mg 20mg 30mg Vials | Lyophilized Powder | CAS  108-94-1-Detailed Image 3


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    Certificates

    Basic Info
    Product Name:

    Cyclohexanone

    Other Name:

    Cyclohexanone;Anone;Hexanon;Hytrol O;Nadone;Pimelic ketone;Pimelin ketone;Sextone;Anon;NSC 5711;C 0489

    CAS No.:

    108-94-1

    UN No.:

    1915

    Molecular Formula:

    C6H10O

    InChIKeys:

    InChIKey=JHIVVAPYMSGYDF-UHFFFAOYSA-N

    Molecular Weight:

    98.14

    Exact Mass:

    98.14

    EC Number:

    203-631-1

    UNII:

    5QOR3YM052

    ICSC Number:

    0425

    NSC Number:

    5711

    UN Number:

    1915

    DSSTox ID:

    DTXSID6020359

    Color/Form:

    OILY LIQUID|WATER-WHITE TO PALE YELLOW LIQUID|Water-white to pale-yellow liquid ...

    HScode:

    2914220000

    Characteristics
    PSA:

    17.07000

    XLogP3:

    0.76

    Appearance:

    Cyclohexanone appears as a colorless to pale yellow liquid with a pleasant odor. Less dense than water . Flash point 111°F. Vapors heavier than air. Used to make nylon, as a chemical reaction medium, and as a solvent.

    Density:

    0.9478 g/cm3 @ Temp: 20 °C

    Melting Point:

    -31 °C

    Boiling Point:

    1.4 °C @ Press: 1.0 Torr

    Flash Point:

    116 °F

    Refractive Index:

    n 20/D 1.450(lit.)

    Water Solubility:

    150 g/L (10 ºC)Flammable. soluble in water.

    Storage Conditions:

    Keep containers closed; prohibit open flame. Store in cool and dark plane.

    Vapor Pressure:

    3.4 mm Hg ( 20 °C)

    Vapor Density:

    3.4 (vs air)

    Toxicity:

    LD50 orally in rats: 1.62 ml/kg (Smyth)

    Flammability characteristics:

    Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.

    Explosive limit:

    vol% in air: 1.1.4 (at 100°C)

    Odor:

    ODOR REMINISCENT OF PEPPERMINT & ACETONE

    PKA:

    11.3None

    OH:

    6.39e-12 cm3/molecule*sec

    Henrys Law Constant:

    9.00e-06 atm-m3/mole

    Dissociation Constants:

    11.3

    Air and Water Reactions:

    Flammable. Soluble in water.

    Reactive Group:

    Ketones

    Reactivity Alerts:

    Highly Flammable

    Reactivity Profile:

    CYCLOHEXANONE forms an explosive peroxide with H2O2, and reacts vigorously with oxidizing materials (nitric acid). (NTP, 1992)

    Peroxide Forming Chemical:

    Cyclohexanone|D*: Other compounds that may form peroxides|9 samples, >1yrs, 1-3 ppm|Management of time-sensitive chemicals (JCHAS)

    Autoignition Temperature:

    788 °F (USCG, 1999)|420 °C; 788 °F|420 °C

    Heat of Combustion:

    -15,430 btu/lb= -8570 cal/g= -358.8x10+5 J/kg

    Ionization Potential:

    9.14 eV

    Flammable Limits:

    Lower flammable limit: 1.1% by volume at 212 °F; Upper flammable limit: 9.4% by volume|Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.

    Physical Dangers:

    The vapour is heavier than air. As a result of flow, agitation, etc., electrostatic charges can be generated.

    Corrosivity:

    Corrosive

    Heat of Vaporization:

    45.06 kJ/mol @ 25 °C

    Critical Temperature & Pressure:

    Critical temp: 673 °F= 356 °C= 629 deg K; Critical pressure: 560 psia= 38 atm= 3.8 MN/sq m

    Hazard Identification

    Classification of the substance or mixture

    Flammable liquids, Category 3

    Acute toxicity - Category 4, Inhalation

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H226 Flammable liquid and vapour

    H332 Harmful if inhaled

    Precautionary statement(s)
    Prevention

    P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

    P233 Keep container tightly closed.

    P240 Ground and bond container and receiving equipment.

    P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.

    P242 Use non-sparking tools.

    P243 Take action to prevent static discharges.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].

    P370+P378 In case of fire: Use ... to extinguish.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P317 Get medical help.

    Storage

    P403+P235 Store in a well-ventilated place. Keep cool.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    NO open flames, NO sparks and NO smoking. Above 44°C use a closed system, ventilation and explosion-proof electrical equipment. Prevent build-up of electrostatic charges (e.g., by grounding). Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Fireproof. Separated from strong oxidants.Keep containers closed; prohibit open flame. Store in cool and dark plane.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    pharmaceutical intermediates,peptides,electronic chemicals

    Location:

    Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

    Payment Terms:

    100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    51-100

    Year of Establishment:

    2024

    A reliable supplier is like insurance.

    We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals,food additives, and other fine chemical products.
    Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

    Website: orientchem.cc
    Email: scarlett@orientchem.cc
    WhatsApp: +86 17753254221

  • Inquiry History
    58 Inquiries
    Country Product Purchase Quantity Date Posted
    Thailand

    Cyclohexanone

    1.00 MT Nov 6, 2024
    Germany

    cyclohexanone

    300 TON Jun 17, 2024
    Thailand

    Cyclohexanone

    1.00 MT Sep 25, 2024
    India

    Cyclohexanone

    50.00 MT Feb 18, 2024
    Netherlands

    Cyclohexanone

    100.00 KG Jun 12, 2025
    United Arab Emirates

    Cyclohexanone

    1.00 20' Fcl Feb 8, 2025
    Pakistan

    Cyclohexanone

    25 MT Sep 23, 2024
    Serbia

    Cyklohekasnone

    20 MT Jun 21, 2026
    Singapore

    Cyclohexanone

    1.00 KG Apr 7, 2026
    India

    Cyclohexanone

    5.00 L Sep 18, 2025
    Egypt

    Cyclo Hexanone

    1.00 MT Jul 1, 2025
    Pakistan

    cyclohexanone

    1 20' Fcl Jun 27, 2025
    India

    cyclohexanone

    1 20' Fcl Jun 6, 2025
    Egypt

    Cyclo Hexanone

    1.00 20' Fcl Mar 14, 2025
    Zimbabwe

    CYCLOHEXANONE

    1 MT Jan 17, 2025
    United States

    Cyclohexanone

    500 G Sep 11, 2024
    Russia

    Cyclohexanone

    70 TON Feb 28, 2024
    Pakistan

    Cyclohexanone

    1.00 20' Fcl Feb 21, 2024
    India

    Cyclohexanone

    1 20' Fcl Feb 16, 2024
    Philippines

    cyclohexanone

    190 KG Jan 12, 2024
    Post an enquiry for this product
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