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Dihexa 1401708-83-5 High Purity Peptide Powder with factory wholesale

Name: Dihexa 1401708-83-5 High Purity Peptide Powder with factory wholesale
Brand: Runlian or as clients' requirement
SKU: pr2606251981
Price: 4.16 USD
Availability: InStock

TDS 180 Inquiries

Unit Price:

$4.16-4.46/BOU FOB

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CAS No.:

1401708-83-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

China

Brand:

Runlian or as clients' requirement

Packaging:

box

Price valid (until):

2027-12-30

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Hangzhou Zhongshuan Technology Co., Ltd.

Company Type:

Trader

Location:

China

Average Lead Time:

15 days

Qualification:

Main Products:

peptide

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Product Details
Seller Information
History Price
Inquiry History

Description

Sales Manager: Judy
Whatsapp: +86 15227650217
Email: 17334330163@163.com
Cartalax – Full Product Description (English, Professional Version)

Basic Information

Product Name: Cartalax
Item No.: LAX20
Specification: 20mg × 10 vials
Appearance: White lyophilized powder, sterile, highly soluble
Purity: ≥98% (HPLC tested)
Formula: Ala‑Glu‑Asp (AED tripeptide)
Class: Tissue‑specific bioregulator peptide (cartilage‑targeted)
Price: $95
Usage: For laboratory research use only

Core Functions & Mechanisms

Cartalax is a synthetic cartilage bioregulator peptide that acts at the gene‑expression level to protect, repair, and maintain articular cartilage and connective tissues.

Epigenetic & Gene Regulation
- Binds directly to chondrocyte DNA promoter regions
- Upregulates SOX9 (master chondrogenic transcription factor)
- Boosts expression of COL2A1 (type II collagen), aggrecan (ACAN), and COMP
- Reduces catabolic pathways driven by Runx2, MMP‑13, ADAMTS‑5
Anabolic Cartilage Repair
- Stimulates chondrocyte proliferation and viability
- Increases synthesis of proteoglycans and glycosaminoglycans (GAGs)
- Strengthens extracellular matrix (ECM) structure and elasticity
- Reduces chondrocyte apoptosis and senescence
Anti‑Inflammatory & Protective Action
- Lowers pro‑inflammatory cytokines (IL‑1β, TNF‑α, NF‑κB)
- Inhibits cartilage‑degrading enzymes
- Reduces joint discomfort and swelling in preclinical models
- Protects against mechanical stress and age‑related degeneration
Joint & Spine Support
- Maintains articular cartilage thickness and integrity
- Supports intervertebral disc health and hydration
- Assists recovery in post‑traumatic and post‑surgical joint research models
- Improves mobility and functional resilience in aging connective tissue

Key Research Applications

Osteoarthritis (OA) cartilage protection and repair
Joint injury rehabilitation and post‑operative recovery
Age‑related cartilage loss and mobility decline
Spine health and intervertebral disc research
Connective tissue aging and senescence studies
Sports medicine and overuse injury models

Advantages

Tissue‑specific: Targets cartilage without broad systemic effects
Gene‑level action: Restores natural chondrocyte function
High purity: ≥98% HPLC; consistent research results
Stable formulation: Lyophilized for long‑term storage

Well‑studied: Supported by decades of bioregulator peptide research

1. Basic Product Information
Parameter	Specification / Value
Product Name	Cartalax
Common Aliases	Ala-Glu-Asp, AED Tripeptide, Cartilage Bioregulator Peptide
Item No.	LAX20
Product Category	Tissue-specific Bioregulator Peptide (Cartilage-targeted)
Intended Use	For laboratory research use only
Brand	Generic research-grade peptide (no proprietary brand in price list)
Origin	Synthetic (chemically synthesized peptide)

Product Detail

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What is Cartalax?

Cartalax (AED) is a synthetic tripeptide bioregulator developed by Professor Vladimir Khavinson and the St. Petersburg Institute of Bioregulation and Gerontology. It consists of three amino acids: Alanine, Glutamic Acid, Aspartic Acid. As a cartilage-targeted peptide, it supports joint health and connective tissue repair by regulating gene expression in chondrocytes.

Key Benefits

✅ Cartilage Regeneration: Promotes type II collagen and proteoglycan synthesis.
✅ Anti-Inflammatory: Inhibits MMPs, IL-1β, TNF-α; reduces joint inflammation.
✅ Joint Mobility: Improves flexibility, relieves stiffness, supports long-term skeletal wellness.
✅ High Bioavailability: Small molecular size ensures rapid absorption and targeted action.

Applications

Research: Osteoarthritis, cartilage degeneration, age-related joint decline.
Formulation: Dietary supplements, joint health products, peptide therapy formulations.
Sports Nutrition: Post-injury recovery, connective tissue support, mobility enhancement.

Storage & Handling

Long-term: Store at -20°C in a dry, dark place.
After reconstitution: Keep at 2–8°C and use within 7 days.
Avoid: Repeated freeze-thaw cycles, moisture, and direct sunlight.

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—— FAQ ——

1.Can we get your free samples?
Yes, can. Our free sample can be provided for customers test. But the freight for express is obuyer's account.

2.How to make an order?
Send me message and let me know what you need with quantity , then i will calculate to you.

3.Can we do printing or label on the bottles?
Yes, can. We can offer various printing ways,such, screen printing, hot stamping, label printing.

4.What is the normal lead time?
For stock products, within 24-48 hours after we receive your payment. For smaller customize color bottles, we will ship out within 3-15 days.

5.What is your shipping terms?
Faster ways: EDEX, DHL, UPS, TNT, etc by sea or by air economy

Pls input...

ECHEMI Editorial Reference

Dihexa is a synthetic peptide-based compound and angiotensin IV analog. As a research and pharmaceutical raw material, Dihexa is characterized by its defined molecular structure and peptide properties. It is primarily used for research, analytical testing, compound evaluation, and pharmaceutical development.

Certificates

Basic Info

Product Name:

Dihexa

Other Name:

L-Isoleucinamide,N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-;N-(1-Oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-L-isoleucinamide;Dihexa;N-Hexanoic-Tyr-Ile-(6)aminohexanoic amide

CAS No.:

1401708-83-5

Molecular Formula:

C27H44N4O5

InChIKeys:

InChIKey=XEUVNVNAVKZSPT-JTJYXVOQSA-N

Molecular Weight:

504.7

Exact Mass:

504.66

Categories:

Bulk Drug Intermediates

Characteristics

Density:

1.111±0.06 g/cm3(Predicted)

Boiling Point:

866.2±65.0 °C(Predicted)

Research

Class:

Angiotensin IV-derived oligopeptide / HGF-c-Met potentiator

Status:

Research compound — Not FDA approved

Mechanism:

A synthetic, orally active, blood-brain-barrier-permeable oligopeptide (Hexanoyl-Tyr-Ile-Ahx-NH₂) derived from angiotensin IV. Dihexa binds hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and allosterically potentiates HGF activity at its receptor c-Met, promoting dendritic spinogenesis and synaptogenesis. In preclinical models it was reported to be seven orders of magnitude more potent than BDNF at promoting synapse formation. Note: the foundational 2014 paper (McCoy AT, et al. Neurobiol Learn Mem. 2014) was retracted in 2025.

EC50 (HGF Binding KD):

65 pM

Activity note:

Dihexa is an HGF potentiator, not a direct receptor agonist. It does not activate c-Met alone but markedly augments HGF-induced c-Met activation at low nanomolar HGF concentrations. Functional synaptogenic activity was reported at 10⁻¹°–10⁻⁻ M (original data now subject to retraction).

Source:

Original report: McCoy AT, et al. Neurobiol Learn Mem. 2014;115:112-120 (retracted 2025). Benoist CC, et al. J Pharmacol Exp Ther. 2014;351(3):628-637.

Clinical Development:

NCT04488419

References

PubChem:

PubChem

UNII:

9WYX65A5C2

Literature:

Benoist CC, et al. J Pharmacol Exp Ther. 2014 — HGF/c-Met mechanism; McCoy AT, et al. Neurobiol Learn Mem. 2014 — Synaptogenesis data (Retracted 2025); Athira Pharma: Fosgonimeton (prodrug) pipeline status

Disclaimer:

Dihexa is NOT FDA-approved or EMA-approved as a medicine. It is a research compound only. The foundational 2014 paper describing its synaptogenic potency was retracted in 2025. Its phosphate prodrug fosgonimeton failed a Phase 2/3 Alzheimer’s trial (LIFT-AD, 2024). This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

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Seller Information

Business Type:
Trader

Main Products:
peptide

Location:
Room A0693, 6th Floor, Building 3, No.5 Lvtai Road, Zhongtai Subdistrict, Yuhang District, Hangzhou City, Zhejiang Province

Average lead Time:
15 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
51-100

Year of Establishment:
2025

Company Certificates
- TR60 COA
Hangzhou ZhongShuan Technology Co., Ltd. specializes in the R&D and manufacturing of pharmaceutical-grade and healthcare-grade bioactive raw materials and their derivatives, which are widely used in pharmaceuticals, nutraceuticals and cosmetics industries and have gained global recognition for superior bioactivity and safety. Our 100,000-square-meter factory is built in strict compliance with GMP standards, boasting a clean production environment, scientific layout, and complete R&D and manufacturing facilities for deep processing of bioactive raw materials and solvent purification, laying a solid foundation for product quality. We are committed to providing global customers with high-quality products and customized professional solutions, and strive to drive product upgrading across various industries through in-depth cultivation of biotechnology.

Global Market Reach
The company's products, with their outstanding quality and stable performance, are exported to over, including the Middle East, South America, North America, Southeast Asia, Africa, Europe, etc., and have accumulated a good reputation in overseas markets. Relying on our professional team and global resource integration capabilities, we fully leverage our geographical and supply chain advantages, continuously optimize localized operations, and effectively help customers reduce costs and improve efficiency while ensuring high-quality products.

Engaged in Raw Materials for 10+ Years
We are a biotech enterprise engaged in the R&D, production, and sales of peptides and raw materials for more than 10 years. The company has complete experimental facilities. Advanced testing instruments ensure the stability of product quality from all aspects. If you're interested in our products, don't hesitate to contact us.
Weekly Price

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Inquiry History

180 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Dihexa	1 KG	Oct 26, 2026
Thailand	Dihexa	1 G	Oct 23, 2026
Australia	Dihexa	30 G	Oct 19, 2026
Australia	Dihexa	2 G	Oct 19, 2026
United States	Dihexa	100 PCS	Oct 15, 2026
United States	Multi-Product Research Chemical Bulk Sourcing Inquiry	2.6 KG	Oct 8, 2026
Philippines	Dihexa	1 KG	Oct 2, 2026
United States	dihexa	10 MG	Sep 28, 2026
Australia	Dihexa	1 MT	Sep 18, 2026
United States	Dihexa	10 G	Sep 9, 2026
Hungary	Dihexa	1 G	Sep 7, 2026
India	Dihexa	10 MG	Sep 4, 2026
Spain	Dihexa	100 MG	Aug 30, 2026
Spain	Dihexa	50 MG	Aug 28, 2026
United Arab Emirates	Diheza	1 G	Aug 28, 2026
Norway	Dihexa	1 G	Aug 26, 2026
Canada	Dihexa lyophilized 1401708-83-5	1	Aug 23, 2026
Canada	SHLP2 ; PE-22-28; Dihexa ; TAK-653 ; lyophilized	10 PCS	Aug 23, 2026
United States	Dihexa	1 G	Aug 22, 2026
United States	Dihexa	500 G	Aug 19, 2026

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Dihexa 1401708-83-5 High Purity Peptide Powder with factory wholesale

Product Details

Seller Information

History Price

Inquiry History

Sales Manager: Judy
Whatsapp: +86 15227650217
Email: 17334330163@163.com
Cartalax – Full Product Description (English, Professional Version)

Basic Information

Core Functions & Mechanisms

Key Research Applications

Advantages

Applications

Storage & Handling

More Choices Find All Products for Sale 

Related Searches

More from this Seller

Dihexa 1401708-83-5 High Purity Peptide Powder with factory wholesale

Product Details

Seller Information

History Price

Inquiry History

Sales Manager: Judy Whatsapp: +86 15227650217 Email: 17334330163@163.com﻿ Cartalax – Full Product Description (English, Professional Version)

Basic Information

Core Functions & Mechanisms

Key Research Applications

Advantages

Applications

Storage & Handling

More Choices Find All Products for Sale 

Related Searches

More from this Seller

Sales Manager: Judy
Whatsapp: +86 15227650217
Email: 17334330163@163.com
Cartalax – Full Product Description (English, Professional Version)