GLP-1 Receptor Binding Peptide, High-Purity Polypeptide for Biochemical & Cell Experiments

Brief Overview GLP-1 (7-36) amide is synthetic freeze-dried polypeptide raw material prepared by solid-phase peptide synthesis and multi-stage chromatographic purification processes. It is exclusively supplied for in-vitro basic academic laboratory research of universities, biomedical research institutions and biotechnology R&D teams, covering receptor binding testing, pancreatic cell metabolic mechanism analysis, endocrine signal cascade exploration, cell model construction and multi-tissue slice co-culture biochemical mechanism research. The finished product is uniform off-white solid powder with stable molecular conformation, which can maintain reliable receptor binding activity and highly repeatable experimental data during long-term cell strain passaging and organ slice cultivation. Multiple vacuum-sealed neutral borosilicate glass vial specifications are available to match various laboratory testing plans: 5mg, 10mg, 20mg. Each batch is attached with full technical documents including independent batch inspection reports and unified technical datasheets, only for internal laboratory filing and academic reference.

Core Laboratory Research Application & Functional Characteristics

Superior Long-Term Structural Stability After Lyophilization Low-temperature vacuum dehydration locks the complete linear polypeptide skeleton and terminal amide modification structure, preventing peptide chain breakage, amino acid hydrolysis and non-specific molecular aggregation during storage and cross-border transportation. Synthetic amino acid chain structure can resist degradation by intracellular proteases, solving the defect of rapid loss of biological activity of liquid medium samples, greatly reducing the repeated reagent preparation workload for long-term laboratory inventory management and continuous cell passaging experiments, and supporting multi-day uninterrupted cell culture experimental schemes without frequent medium replenishment.

Wide Compatibility With Conventional Mammalian Cell Culture Systems This freeze-dried powder can be fully dissolved in laboratory dedicated bacteriostatic purified water and neutral PBS buffer solution with adjusted pH value. It is compatible with conventional pancreatic beta cells, endothelial cells, mesenchymal stem cells, epithelial precursor cells and multi-tissue slice testing systems, will not introduce foreign contaminants that disturb the cell growth microenvironment, and will not trigger abnormal cytotoxic responses within the standard research concentration range.

Stable Concentration Gradient Response Characteristics Adjustable working concentrations adapt to customized experimental designs; multiple detection indicators including metabolic enzyme synthesis level, intracellular secondary messenger concentration and cell proliferation ratio show stable linear changes with concentration gradients, facilitating quantitative data statistics and academic paper graph drawing for basic polypeptide signal research.

Ultra-Low Background Interference For Detection Analysis Multi-stage layered reversed-phase chromatographic purification removes residual truncated polypeptide fragments, incomplete synthesis by-products, free amino acid impurities and endotoxin contaminants in finished solid products. It will not generate extra noise signals for spectrophotometers, fluorescence detectors and cell proliferation colorimetric testing equipment, delivering reliable and clear biochemical quantitative detection results and stable repeatability for cell signal verification experiments.

Consistent Batch Performance Across All Production Batches The integrated standardized production process including solid-phase peptide synthesis, terminal amidation modification, multi-step chromatographic purification and vacuum freeze-drying ensures unified polypeptide purity, molecular structural integrity and receptor binding signal regulation performance of all batches. It avoids experimental result deviations caused by inconsistent raw material synthesis batches, supporting parallel control experiments and repeated result verification for laboratory teams engaged in endocrine cell metabolic signal research.

Complete Standard Physical & Chemical Specification Parameters Basic Product Identification Information Full Standard Product Name: GLP-1 (7-36) Amide Endocrine Signal Laboratory Culture Solid Research Reagent Alias: GLP-1 (7-36) Amide Synthetic Polypeptide Cell Metabolism Laboratory Freeze-Dried Powder Peptide Sequence: Standard 30-residue linear L-amino acid chain with C-terminal amide modification Molecular Formula: C₁₄₉H₂₂₆N₄₀O₄₅ Theoretical Molecular Weight: 3297.62 Da CAS No.: 107444-51-9 Appearance Morphology: Uniform off-white freeze-dried solid powder, free of caking, discoloration, yellow/brown oxidation spots, tiny foreign particles or visible insoluble impurities Odor Feature: Completely odorless Solubility Characteristic: Fully miscible with laboratory bacteriostatic purified water and neutral PBS buffer liquid; insoluble in alcohol-based organic solvents, aqueous buffer solubility ≥250mg/mL Reconstituted Liquid Appearance: Transparent colorless clear liquid after full gentle dissolution, without turbidity, floccules, sediment or suspended particles pH Value of Standard 1mg/mL aqueous mixed solution: 7.0 ~ 8.0 Residual Moisture Index: ≤ 8.0% (tested by Karl Fischer titration for each separate batch) Acetate Content: 5.0% – 12.0% Endotoxin Level: ≤ 50 EU/mg, fully compliant with global universal biosafety standards for in-vitro cell basic laboratory research Total Heavy Metal Impurity Limit Standard: Comprehensive total heavy metal pollutants ≤10ppm (integrated combined detection of various heavy metal elements, no separate marking of single metal elements) Microbiological Control Standard: Total aerobic bacteria <10 CFU/mg, mold & yeast <5 CFU/mg; no pathogenic microorganisms detected in all finished batches Molecular Structural Integrity Standard: Each batch is verified by spectrum matching, peptide mapping and mass spectrometry to confirm intact full amino acid chain and complete C-terminal amide modification structure, without peptide chain breakage or amino acid hydrolysis defects

Quality Control Benchmark

Standard Step-by-Step Dissolving Operation Guidance Recommended Matching Solvent Medium: Laboratory dedicated bacteriostatic purified water / pH 7.0–8.0 neutral PBS buffer

Storage Environment & Valid Usage Cycle Specifications Unopened Original Vacuum-Sealed Vials Long-term sealed storage condition: Store fully sealed vials at -20℃, completely shielded from direct sunlight and high ambient humidity (photosensitive and hygroscopic polypeptide must avoid repeated exposure to humid air and strong light irradiation) Valid stable storage period under constant -20℃ freezing environment: 36 months Short-distance transportation stability tolerance: It can retain complete receptor binding signal activity for up to 7 days under ambient temperature ≤25℃, and light-proof packaging must be used during transportation Forbidden storage operations: Frequent repeated temperature cycle fluctuations, long-time continuous direct sunlight exposure, storage beside volatile oxidizing organic chemical reagents, repeated opening of sealed vials in humid atmospheric environment Liquid Mixed With Bacteriostatic Purified Water / PBS Buffer After Full Dissolution Storage condition after complete dissolution: Place in a refrigerator at -80℃ ultra-low temperature environment, fully shaded from light and tightly sealed Suggested full consumption time limit: Use up all mixed liquid within 12 months after preparation completion Strict prohibition rule: Do not repeatedly freeze and thaw the diluted mixed liquid; repeated freeze-thaw cycles will permanently damage the polypeptide skeleton and terminal amide coordination stability, completely losing the metabolic signal regulation activity required for endocrine cell culture research

Shipping & Receiving Handling Reminders Small trial vial orders can be delivered via standard international express for short-distance cross-border transportation routes, equipped with light-proof outer packaging and ice packs for low-temperature protection Large multi-vial batch orders are highly recommended to adopt temperature-insulated foam protective packaging equipped with sufficient ice packs and full light-proof outer bags to maintain the stable molecular structure of synthetic polypeptide during long-distance overseas transportation Complete supporting shipping documents will be delivered together with all parcels, including unified technical datasheets, batch exclusive COA test records and molecular structural verification files, for customs inspection and internal laboratory filing use

Laboratory Operation Safety Precautions Wear disposable nitrile protective gloves, transparent impact-resistant safety goggles and dust-proof laboratory masks during solid powder weighing and liquid dissolving operation processes Avoid direct skin contact, eye mucous membrane contact and inhalation of dry freeze-dried cell signal polypeptide solid powder In case of accidental contact with skin or eye tissue, immediately flush the affected area thoroughly with a large amount of clean running water continuously for no less than 5 minutes Dispose residual solid powder and waste mixed liquid in strict accordance with the internal biosafety waste management rules of your laboratory; never pour waste liquid directly into domestic drainage pipelines or ordinary household garbage bins

Important Usage Restriction & Disclaimer Statement This GLP-1 (7-36) amide polypeptide solid reagent is exclusively developed for fundamental scientific research projects of universities, biomedical research institutes and biotechnology R&D teams. This product is not medical supplies, therapeutic raw materials or cosmetic ingredient raw materials, and has not obtained official regulatory authorization from global supervision authorities for any human body intervention use, oral intake or animal disease diagnosis and treatment. Resale to individual private users for personal physical conditioning or unregulated self-use is strictly prohibited. Any human-related experimental research can only be carried out after obtaining formal written regulatory approval documents.

Free Supporting Technical Documents Provided Upon All Shipment Order Completion After order shipment completion, all customers can receive a full set of free complete technical archive files: