Anti-Inflammatory Mitochondrial SS-31 Synthetic Peptide Suppressing NLRP3 Inflammasome Activation Research CAS 736992-21-5
TDS 29 Inquiries
736992-21-5
Pharmaceutical Grade
99%
Hong Kong
TRANMOO
10mg*10vials,50mg*10vials
Yes
2050-06-01
Retatrutide
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceElamipretide has been used in trials studying the treatment of Leber's Hereditary Optic Neuropathy.
Elamipretide, also known as MTP 131, is a mitochondria-targeted peptide antioxidant. Elamipretide decreases inflammation and protect against a variety of neurological illnesses. Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice. Elamipretide Promotes Mitophagosome Formation and Prevents Its Reduction Induced by Nutrient Excess in INS1 β-cells.
Elamipretide Synthetic is a single, non-glycosylated polypeptide chain containing 4 amino acids, having a molecular mass of 640 Dalton and a Molecular formula of C32H49N9O5 .CertificatesBasic Info-
Product Name:
Elamipretide
Other Name:D-Arginyl-2,6-diMethyl-L-tyrosyl-L-lysyl-L-phenylalaninaMide;Elamipretide;L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-;Elamipretide (TFA salt);SS-31;MTP-131;BENDAVIA;Bendavia);Elamipretide (SS-31;ELAMIPRETIDE, >99%
CAS No.:736992-21-5
Molecular Formula:C32H49N9O5
InChIKeys:SFVLTCAESLKEHH-WKAQUBQDSA-N
Molecular Weight:639.79
Exact Mass:639.38566570
EC Number:205-858-1
UNII:87GWG91S09
DSSTox ID:DTXSID50471988
Color/Form:White to Off-White
Categories:
Characteristics-
Density:
1.34±0.1 g/cm3(Predicted)
PKA:10.10±0.25(Predicted)
Research-
Class:
Mitochondria-targeted tetrapeptide (Szeto-Schiller peptide)
Status:FDA-approved (Forzinity) — Accelerated Approval 2025
Mechanism:A cell-permeable, synthetic tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) that selectively concentrates in the inner mitochondrial membrane and reversibly binds to cardiolipin, a phospholipid essential for electron transport chain (ETC) function. By stabilizing cardiolipin, SS-31 restores mitochondrial bioenergetics, reduces cytochrome c peroxidase activity, and prevents oxidative damage in cells with impaired mitochondrial function.
Activity note:SS-31 does not act via traditional receptor agonism. It binds cardiolipin with high selectivity in the inner mitochondrial membrane. Functional EC₅₀ values are context-dependent (cell type, stress model). Key electrophysiology studies report mitochondrial membrane potential restoration at nanomolar concentrations.
Source:Szeto HH, et al. AAPS J. 2006;8(2):E277-E283. Birk AV, et al. J Am Soc Nephrol. 2014;25(6):1157-1169.DOI
Clinical Development:FDA:Forzinity (approved 2025-09-19)
References-
ChEMBL:DrugBank:KEGG DRUG:PubChem:Literature:
FDA: Forzinity (NDA 215244) — Accelerated Approval 2025; Genetics in Medicine: TAZPOWER Phase 2/3 results (Thompson et al. 2020); Drugs: Elamipretide First Approval (Springer 2025)
Disclaimer:Elamipretide (Forzinity) is FDA-approved under accelerated approval for Barth syndrome. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Retatrutide
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Location:
shenzhenshilonggangqulongchengjiedaohuanggekengshequjiazhaoyeshidaidasha902
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Average lead Time:
15 days
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Year of Establishment:
2024
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Inquiry History29 Inquiries
Country Product Purchase Quantity Date Posted
United States
SS-31
1 KG May 7, 2026
United States
SS-31
1 G Mar 30, 2026
United States
ss31
1 KG Mar 16, 2026
United States
SS 31
1 KG Jan 12, 2026
United States
SS-31
50 MG Dec 10, 2025
United States
Ss31
1 KG Dec 9, 2025
Canada
Ss31
1 G Jul 24, 2026
United States
SS31
30 MG May 27, 2026
United States
SS31
25 MG May 26, 2026
United States
Ss 31
1 KG Mar 18, 2026
United States
SS-31
10 MG Jan 30, 2026
Denmark
ss31
1 KG Jan 4, 2026
Brazil
SS-31
1 MG Dec 20, 2025
United Kingdom
ss31
1 G Nov 19, 2025
United States
SS31
30 MG Sep 20, 2026
United States
SS-31
50 MG Sep 8, 2026
Australia
SS-31
30 MG Aug 24, 2026
United States
Elamipretide
200 MG Apr 27, 2026
United States
SS-31
1 KG Apr 24, 2026
United States
ss-31
500 MG Apr 13, 2026 Post an enquiry for this product
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