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Home > Biochemical Engineering > Polypeptide > Semaglutide for Sale > Top Grade Semaglutide 99% Purity White Lyophilized Powder Multiple Specifications CAS NO.910463-68-2
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Top Grade Semaglutide 99% Purity White Lyophilized Powder Multiple Specifications CAS NO.910463-68-2

COA 425 Inquiries

Unit Price:

$40-50/UNIT EXW

Get Latest Price
CAS No.:

910463-68-2

Content:

99%

Packaging:

carton

Price valid (until):

2026-12-31

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,100% TT in advance
Average Lead Time:
15 days
Qualification:
Main Products:

Peptide

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Semaglutide Introduction

    Semaglutide is the newest GLP-1R agonist and was approved by the FDA as a once-weekly  for the treatment of T2DM in late 2017. The peptide is chemically similar to liraglutide, with the inclusion of two structural modifications (Lau, Bloch, et al., 2015). The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position 2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans.


    Function

    Glucose-dependent hypoglycemic effect

    It stimulates insulin secretion and suppresses glucagon (the blood sugar-raising hormone) when blood glucose levels rise; it exerts no hypoglycemic effect when blood glucose is normal, resulting in an extremely low risk of hypoglycemia when used alone.

    Appetite control and weight loss

    It delays gastric emptying to prolong satiety, acts on the appetite center in the hypothalamus of the brain, reduces food cravings and cuts total calorie intake.

    Cardiorenal protection

    It lowers blood pressure and improves blood lipid profiles, reducing the risks of myocardial infarction, stroke, heart failure and progressive kidney disease. It is one of the few anti-diabetic drugs approved to deliver cardiovascular benefits.
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    company profile

      Guangzhou Boyuan Outdoor Products Co., Ltd. is a trading company headquartered in Guangzhou, one of southern China's most prominent commercial and logistics hubs. Leveraging the city's well-established supply chain infrastructure and international trade channels, the company has evolved from its original focus on outdoor consumer goods into a specialized supplier of high-purity biochemical reagents and peptide derivatives. While the company retains "Outdoor Products" in its registered name, its current core business centers on providing stable, non-hazardous, and laboratory-grade peptide derivatives to qualified research institutions, universities, and commercial laboratories worldwide.

      Boyuan operates under a clear and responsible business philosophy: professionalism, consistency, and traceability. All products offered by the company are positioned strictly as general chemical reagents and laboratory research materials. They are not classified as pharmaceuticals, medical devices, hazardous chemicals, or products intended for human therapeutic, diagnostic, or preventive applications. The company strictly adheres to national and international regulations governing the trade and logistics of non-hazardous chemical products, ensuring that every step—from procurement and quality inspection to warehousing and domestic or international shipping—remains compliant, safe, and fully traceable.

      Based on market feedback, Boyuan's products have received high praise from customers, who generally agree that the products have stable purity, rapid reconstitution, good batch-to-batch consistency, and clear advantages in price compared to similar suppliers. Many customers specifically mention Boyuan's professionalism in packaging and logistics, noting that the cold chain packaging is robust with sufficient ice packs, ensuring the product remains in good lyophilized condition even after long-distance transportation. The company has established long-term and stable cooperative relationships with research institutions and distributors from countries such as the United States, Germany, the United Kingdom, Australia, Brazil, and South Korea. Boyuan will continue to develop in the peptide field, enriching its product line, improving quality control standards, optimizing its global logistics network, and actively exploring cooperation opportunities with research institutions. The company plans to introduce more novel peptide products in the future, including but not limited to research molecules such as MOTS-c, SS-31, and FOXO4, while further improving the product traceability system and customer service system. Boyuan believes that through continuous effort and innovation, it can provide global researchers with a better, more convenient, and more reliable experience in sourcing peptide raw materials.

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    Items Specifications
    Product Name Semaglutide
    CAS No. 910463-68-2
    Specification 5mg 10mg 15mg 20mg 30mg 40mg 50mg
    Purity 99%
    Origin China
    ECHEMI Editorial Reference

    Semaglutide (CAS: 910463‑68‑2) is a synthetic lipid‑modified peptide analogue, consisting of a 31‑amino‑acid backbone with a covalently attached C18 fatty di‑acid side‑chain via a hydrophilic spacer. It shares 94% amino‑acid sequence homology with native human GLP‑1 peptide. The substance appears as white to almost white hygroscopic powder, with molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and molecular weight of 4113.58 g/mol. Structural modifications grant it resistance against DPP‑4 enzymatic degradation and enable reversible binding to serum albumin, contributing to its extended in‑vivo half‑life property.

    Certificates

    Basic Info
    Product Name:

    Semaglutide

    Other Name:

    Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide

    CAS No.:

    910463-68-2

    Molecular Formula:

    C187H291N45O59

    InChIKeys:

    DLSWIYLPEUIQAV-CCUURXOWSA-N

    Molecular Weight:

    4113.57754

    Exact Mass:

    4113.122087 g/mol

    EC Number:

    203-405-2

    Color/Form:

    White to off-white

    Categories:

    Polypeptide

    Characteristics
    PSA:

    1650 Ų

    XLogP3:

    5.44520

    Critical Temperature & Pressure:

    Store at -20°C

    Research
    Class:

    GLP-1R agonist

    Status:

    FDA-approved (Ozempic / Wegovy / Rybelsus)

    Mechanism:

    Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

    Activity note:

    Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

    Source:

    Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

    Clinical Development:

    NCT03548935; NCT03552757; NCT01720446; NCT02692716

    FDA:

    Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

    References
    ChEMBL:

    CHEMBL2108724

    DrugBank:

    DB13928

    KEGG DRUG:

    D10025

    PubChem:

    PubChem

    Disclaimer:

    Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptide

    Location:

    Room Z567,17th Floor,BuildingA,No.298 Yanjiang Middle Road,Yuexiu District,Guangzhou

    Payment Terms:

    TT against copy of documents,100% TT in advance

    Average lead Time:

    15 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2026

  • Inquiry History
    425 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Weight Loss Semaglutide intermediate 99% White powder COA High Quality peptide GLP-1 910463-68-2

    5 MG Apr 11, 2024
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    2  Dec 5, 2023
    China

    Semaglutide CAS 910463-68-2

    1 KG Apr 16, 2026
    United Kingdom

    TGYFactory Supply Semaglutide Peptide 99% CAS 910463-68-2

    50 MT Nov 13, 2023
    Sri Lanka

    Bulk Supply 98% up Sermaglutide powder CAS 910463-68-2

    300 G Nov 18, 2023
    China

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    60 MG Aug 4, 2025
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    10 MT Sep 19, 2025
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    2  Nov 13, 2024
    United States

    semaglutide CAS 910463-68-2 in stock 2-4 days safe delivery

    1 MT Nov 4, 2023
    India

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    100  Nov 8, 2023
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    50 MT Nov 11, 2023
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    GLP-1 Injection Weight Loss Tirzepatide Semaglutide 99% Purity Peptides CAS: 910463-68-2

    1 MT Oct 25, 2023
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    United Kingdom

    Weight Loss GLP-1 Peptides Purity 99% Wholesales Price 2mg 5mg 10mg Semaglutide CAS: 910463-68-2

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    l Weight Loss Semaglutide Tirzepatide Epitalon Retatrutide pharma Peptides Liraglutide CAS: 910463-68-2 Retatrutide CAS 2381089-83-2 Ly34379

    20 MT Nov 13, 2023
    Canada

    Semaglutide

    1 G Jun 24, 2024
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