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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Osimertinib mesylate for Sale > Osimertinib Mesylate CAS 1421373-66-1 Third-Generation EGFR TKI for NSCLC Research Reference Standard kr
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Osimertinib Mesylate CAS 1421373-66-1 Third-Generation EGFR TKI for NSCLC Research Reference Standard kr

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Unit Price:

$120-150/G FOB

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CAS No.:

1421373-66-1

Grade:

Pharmaceutical Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

1g/vial, 5g/vial, 10g/vial, 25g/vial, 100g/vial

Price valid (until):

2026-08-07

Company Type:
Trader
Location:
China
Qualification:
Main Products:

3-(1-Naphthoyl)indole

  • Product Description

  • Seller Information

  • Description

    —— Product Specification ——

    Product Name Osimertinib Mesylate AZD-9291 Mesylate, Mereletinib Mesylate
    CAS Number 1421373-66-1 1421373-66-1
    Molecular Formula C₂₉H₃₇N₇O₅S 29 carbons, 37 hydrogens, 7 nitrogens, 5 oxygens, 1 sulfur
    Molecular Weight 595.71 g/mol
    Appearance White to off-white or light yellow solid powder Visual inspection
    Purity ≥98.0% Determined by HPLC
    Melting Point >232°C (dec.)
    Solubility Soluble in DMSO, methanol
    Storage -20°C, inert atmosphere, protect from light and moisture Sealed containers
    Packaging 10mg, 25mg, 50mg, 100mg, 500mg, 1g Amber glass vials
    Application Research use only NSCLC research, kinase modulation studies, reference standard


    —— Product Detail ——

    Product Overview

    Osimertinib Mesylate (CAS 1421373-66-1), also known as AZD-9291 Mesylate or Mereletinib Mesylate, is the mesylate salt form of osimertinib, an orally bioavailable, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase modulator . It appears as a white to off-white or light yellow solid powder with the molecular formula C₂₉H₃₇N₇O₅S and a molecular weight of 595.71 g/mol .

    With a purity of ≥98.0% by HPLC, Osimertinib Mesylate is a well-established pharmaceutical compound approved for the treatment of non-small cell lung cancer (NSCLC) harboring EGFR mutations (exon 19 deletions or L858R) and the T790M resistance mutation


    Packaging & Shipping

    • Research quantities: 10mg, 25mg, 50mg amber glass vials

    • Bulk quantities: 100mg, 500mg, 1g amber glass bottles

    • Custom packaging available upon request

    • Not classified as hazardous material for transport under normal conditions

    • Product for research and analytical use only; not for human or veterinary use

    Company profile ——


     Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 1

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

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    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    Certificates
    • Osimertinib Mesylate CAS 1421373-66-1 Third-Generation EGFR TKI for NSCLC Research  Reference Standard kr Certificates 1

    Basic Info
    Product Name:

    Osimertinib mesylate

    Other Name:

    AZD-9291 (Mesylate);N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);AZD-9291 mesylate N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);Osimertinib;N-[2-(2-dimethylaminoethylmethylamino)-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide mesylate salt;Osimertinib Mesylate(AZD9291);Osimertinib mesylate;Mereletinib mesylate

    CAS No.:

    1421373-66-1

    Molecular Formula:

    C29H37N7O5S

    InChIKeys:

    FUKSNUHSJBTCFJ-UHFFFAOYSA-N

    Molecular Weight:

    595.72

    EC Number:

    200-064-1

    Color/Form:

    Off-White to Yellow

    HScode:

    29339900

    Characteristics
    Melting Point:

    >232°C (dec.)

    Critical Temperature & Pressure:

    -20°C Freezer, Under inert atmosphere

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Skin sensitization, Sub-category 1B

    Reproductive toxicity, Category 2

    Specific target organ toxicity – repeated exposure, Category 1

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H302 Harmful if swallowed

    H317 May cause an allergic skin reaction

    H361 Suspected of damaging fertility or the unborn child

    H372 Causes damage to organs through prolonged or repeated exposure

    H400 Very toxic to aquatic life

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P203 Obtain, read and follow all safety instructions before use.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P273 Avoid release to the environment.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P321 Specific treatment (see ... on this label).

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    3-(1-Naphthoyl)indole

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Country Product Purchase Quantity Date Posted
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