 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate for Sale > (2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane144164-11-4

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane144164-11-4 buy - large image1

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane144164-11-4 buy - image1

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane144164-11-4 buy - image2

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane144164-11-4 buy - image3

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane144164-11-4 buy - image4

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane144164-11-4

Name: (2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane144164-11-4
Brand: OORENT
SKU: pr2607083008
Price: 33 USD
Availability: InStock

3 Inquiries

Unit Price:

$33-34/MT FOB

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CAS No.:

144164-11-4

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

OORENT

Packaging:

vial

Price valid (until):

2026-08-08

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

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Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Detail

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane Basic information

Product Name:	(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane
Synonyms:	2S,3S,5S-5-AMINO-2-[N-[[(5-THIAZOLYL)METHOXY]CARBONYL]AMINO]-1,6-DIPHENYL-3-HYDROXYHEXANE;RIT-X;Thiazol-5-ylMethyl ((2S,3S,5S)-5-aMino-3-hydroxy-1,6-diphenylhexan-2-yl)carbaMate;1,3-Thiazol-5-ylMethyl N-[(1S,2S,4S)-4-aMino-1-benzyl-2-hydroxy-5-phenylpentyl]car baMate;(5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamic acid;Carbamic acid,N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-,5-thiazolylmethyl ester;(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane###144164-11-4;Ritonavir Impurity 1
CAS:	144164-11-4
MF:	C23H27N3O3S
MW:	425.54
EINECS:
Product Categories:	Aromatics;Chiral Reagents;Heterocycles;Intermediates
Mol File:	144164-11-4.mol

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane Chemical Properties

Boiling point	656.1±55.0 °C(Predicted)
density	1.251±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	11.48±0.46(Predicted)
color	Off-White to Pale Yellow

Safety Information

MSDS Information

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane Usage And Synthesis

Chemical Properties	Light Yellow Oil
Uses	An intermediate in the synthesis of Ritonavir.
Synthesis	162849-95-8 144164-11-4 Example 4. Preparation of (2S,3S,5S)-5-amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane: (2S,3S,5S)-5-(tert-butoxycarbonylamino)-2-(N-5-thiazolylcarbonylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane (1.2g, 6.2 mmol) was dissolved in 4N HCl/dioxane solution (12 mL) and the reaction was stirred for 3 hours at room temperature. After completion of the reaction, the mixture was concentrated under vacuum and the residue was ground with EtOAc and filtered to give a white solid product (0.93 g, 98.2% yield). The product was characterized by 1H NMR (300MHz, DMSO-D6): δ 1.58 (t, J = 6.3Hz, 2H), 2.54-2.68 (m, 1H), 2.72-2.93 (m, 3H), 3.41-3.55 (m, 1H), 5.13 (s, 2H), 7.04-7.47 (m, 11H), 7.84 (s, 1H), 9.07 (s, 1H). 1H), 9.07 (s, 1H); MS (ESI) m/z 426.1 (M + H)+.
References	[1] Patent: WO2008/27932, 2008, A2. Location in patent: Page/Page column 96 [2] Patent: WO2006/90264, 2006, A1. Location in patent: Page/Page column 22-23 [3] Patent: WO2006/90270, 2006, A1. Location in patent: Page/Page column 11 [4] Patent: EP1170289, 2002, A2. Location in patent: Page 45 [5] Patent: WO2005/111006, 2005, A1. Location in patent: Page/Page column 17-18

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane Preparation Products And Raw materials

Raw materials	(2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane-->Hydrochloric acid-->1,4-Dioxane
Preparation Products	Ritonavir

Pls input... Shop TRANS-2-DECEN-1-OL18409-18-2-Detailed Image 2

Basic Info

Product Name:

1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate

Other Name:

Carbamic acid,N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-,5-thiazolylmethyl ester;Carbamic acid,[4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-,5-thiazolylmethyl ester,[1S-(1R*,2R*,4R*)]-;Carbamic acid,[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-,5-thiazolylmethyl ester;1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate

CAS No.:

144164-11-4

Molecular Formula:

C23H27N3O3S

InChIKeys:

InChIKey=HBPTXDXGWDVDON-BVSLBCMMSA-N

Molecular Weight:

425.544

Exact Mass:

425.54

DSSTox ID:

DTXSID10455244

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

125.71000

XLogP3:

3.27

Appearance:

Light yellow oil

Density:

1.3±0.1 g/cm3

Boiling Point:

656.1±55.0 °C at 760 mmHg

Flash Point:

350.6±31.5 °C

Refractive Index:

1.620

Vapor Pressure:

4.17E-18mmHg at 25°C

See More 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

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We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
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Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
Netherlands	(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane	100 G	Jul 8, 2026
India	(2S,3S,5S)-5-Amino-2-(n-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane	25 G	Nov 6, 2025
India	(2S,3S,5S)-5-amino-2-(N-((5-thiazolyl)methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane	2 MT	May 30, 2025

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(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane	Pharmaceutical Grade/98		Echemi Pharmaceutical	Inquiry
Ritonavir Impurity 1	/		Shandong zhishang chemical Co.,Ltd	Inquiry
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(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane.	/		Hefei Heyu Chemical New Materials Co., Ltd	Inquiry