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What is GHK-Cu ?

   GHK-Cu is a complex of the tripeptide Gly-His-Lys and a copper(II) ion that has wound healing and anti-inflammatory activities. It increases proliferation and the levels of collagen and secreted pro-matrix metalloproteinase-2 (MMP-2) in isolated human fibroblasts. GHK-Cu increases levels of collagen and glycosaminoglycans (GAGs) and the expression of decorin in the wound tissue of rats. It decreases LPS-induced increases in the levels of reactive oxygen species (ROS), IL-6, and TNF-α in RAW 264.7 cells when used at a concentration of 10 µM.3 GHK-Cu (10 µg/g) prevents LPS-induced decreases in lung superoxide dismutase (SOD) activity and glutathione (GSH) levels and reduces LPS-induced increases in the number of cells and the level of total protein in bronchoalveolar lavage fluid (BALF) in a mouse model of acute lung injury.

  Many active substances in the human body are in the form of peptides. Peptides are involved in various fields of human hormones, nerves, cell growth and reproduction, and their importance is to regulate the physiological functions of various systems and cells in the body, activate the relevant enzyme systems in the body, promote the permeability of intermediate metabolic membranes, or control DNA transcription or affect specific protein synthesis, and ultimately produce specific physiological effects. Peptides are important substances involved in various cell functions in human body. Peptides can be synthesized into cells and regulate their functional activities. Peptides act as neurotransmitters in the body, transmitting information.

• Items	Specifications
  Product Name	GHK-Cu
  Form	Solid freeze-dried powder
  Storage condition	-20°C
  Purity	99%
  Packaging	Bottle, Can, Drum, Plastic Container, Vacuum Packet (According to customers' requirements)
  Trademark	Customzied accepted

    1. Anti-tumor effect and DNA repair
A variety of tumor cell lines have been shown to be suppressed or die in the presence of this compound while healthy cell lines continued to grow normally. This and other evidence implies that copper tripeptide-1 may be used in topical products to enhance normal tissue repair without fear of neoplastic transformation.
    2. Stem cell anti-senescence
Survival of stem cells in the basal epidermis and other epithelial cells is promoted by tripeptide-1. This suggests it could have an important anti-ageing effect, and in fact, its anti-senescent effects have been demonstrated on a number of tissue types including skin. Keratinocyte proliferation is encouraged through stem cell maintenance encouraged via copper tripeptide-1.
   3. Antioxidant and anti-inflammatory effects
Many of the body's intrinsic antioxidant systems, including superoxide dismutase, are induced by copper tripeptide-1.

    Hong Kong City Trade Co., Ltd. was established in 2019 and possesses strong R&D capabilities, excellent synthesis technology, and advanced quality control measures. We effectively collaborate with major companies and manufacturers, and serve society and a wide range of users based on the principles of industrial development. We consistently focus on market demand, continuously synthesizing new chemical products and pharmaceutical intermediates with high technological content, primarily exporting to the United States, India, South Africa, Nigeria, and many other countries and regions. We have extensive export experience to ensure safe transportation and guarantee that every customer receives their goods safely and promptly.