—— Product Specifications ——
—— Product Detail ——
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Product Overview
3-(4-tert-Butylpyridin-2-yl)benzonitrile is a heterocyclic organic compound with the molecular formula C₁₆H₁₆N₂ and a molecular weight of 236.31 g/mol. This white to off-white crystalline powder features a pyridine ring substituted with a tert-butyl group at the 4-position and a benzonitrile moiety at the 2-position, making it a valuable building block for pharmaceutical research and ligand synthesis. The compound's combination of a pyridine nitrogen and a nitrile group provides versatile coordination and functionalization capabilities.
Synthetic Process
3-(4-tert-Butylpyridin-2-yl)benzonitrile is synthesized through the following routes:
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Suzuki coupling: 2-Bromo-4-tert-butylpyridine is coupled with 3-cyanophenylboronic acid under palladium-catalyzed conditions.
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Purification: The crude product is purified by column chromatography or recrystallization.
Mechanism of Action / Application Principles
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Ligand Synthesis: The pyridine nitrogen serves as a coordinating site for metals, useful in catalysis and materials science.
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Pharmaceutical Intermediate: Used in the synthesis of bioactive molecules targeting various therapeutic areas.
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Organic Electronics: Pyridine derivatives are used in the synthesis of organic semiconductors and light-emitting materials.
Quality Specifications
| Parameter | Specification |
| Assay | ≥98.0% |
| Appearance | White to off-white crystalline powder |
| Melting Point | 98 - 102°C |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
Each batch is accompanied by a Certificate of Analysis (COA).
Packaging & Storage
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Research quantities: 100mg, 500mg amber glass vials
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Bulk quantities: 1g, 5g HDPE containers
Storage conditions: Store in a cool, dry place in tightly sealed containers, protected from light. Under recommended conditions, shelf life is 24 months.
— C ompany Profile ——
Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.
Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.
We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.
To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.
Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.
—— Q&A ——
Q1: How to confirm the product quality before placing orders?
A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.
Q2: Can you supply free samples?
A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.
Q3: How do you treat quality complaints?
A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.
Q4: What is your MOQ? Is there a discount?
A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantities, we always support with better prices.
Q5: How to start orders or make payments?
A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.