Duloxetine hydrochloride CAS.136434-34-9
1 Inquiries
136434-34-9
Pharmaceutical Grade
99%
Shenzhen
Flying
10g/1kg/ 10kg/ 25kg
2026-08-25
vitamin
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceIn addition, duloxetine recipients experienced significantly greater increases in their average voiding interval than placebo recipients (15.0–20.4 versus 1.7–8.5 minutes). The most commonly observed adverse events associated with duloxetine therapy are nausea, dry mouth, constipation, decreased appetite, fatigue, somnolence, and increased sweating. As with other 5-HT reuptake inhibitors, duloxetine is contraindicated in patients taking MAO inhibitors. Additionally, it is contraindicated
(S)-duloxetine hydrochloride is a duloxetine hydrochloride in which the duloxetine moiety has S configuration. It has a role as an antidepressant. It contains a (S)-duloxetine.|Duloxetine Hydrochloride is the hydrochloride salt of duloxetine, a fluoxetine derivative belonging to the class of selective serotonin (5-HT) and norepinephrine (NE) reuptake inhibitors (SSNRIs) and exhibiting antidepressant activity. Duloxetine selectively prevents the reuptake of 5-HT and NE via transporter complexes on the pre-synaptic membrane, thereby increasing the level of these neurotransmitters within the synaptic cleft. As a result, this agent potentiates serotonergic and noradrenergic activities in the central nervous system, and alleviates depression and neuropathy sensations, such as pain and tingling. Furthermore, duloxetine does not show significant affinity for dopaminergic, adrenergic, cholinergic, histaminergic, opioid, glutamate, and gamma-aminobutyric acid (GABA) receptors.|A thiophene derivative and selective NEUROTRANSMITTER UPTAKE INHIBITOR for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC, and is also used for the treatment of pain in patients with DIABETES MELLITUS and FIBROMYALGIA.Basic Info-
Product Name:
Duloxetine hydrochloride
Other Name:2-Thiophenepropanamine,N-methyl-γ-(1-naphthalenyloxy)-,hydrochloride (1:1),(γS)-;2-Thiophenepropanamine,N-methyl-γ-(1-naphthalenyloxy)-,hydrochloride,(S)-;2-Thiophenepropanamine,N-methyl-γ-(1-naphthalenyloxy)-,hydrochloride,(γS)-;LY 248686 HCl;(S)-(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride;Duloxetine hydrochloride;Cymbalta;(S)-Duloxetine hydrochloride;(S)-(+)-Duloxetine hydrochloride;Dulane 20;(S)-γ-(1-Naphthalenoxy)-N-methylthiophene-2-propanamine monohydrochloride;(S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride;Yentreve;Irenka;Drizalma Sprinkle
CAS No.:136434-34-9
Molecular Formula:C18H19NOS.ClH
InChIKeys:InChIKey=BFFSMCNJSOPUAY-LMOVPXPDSA-N
Molecular Weight:333.88
Exact Mass:333.095398
EC Number:200-659-6
UNII:9044SC542W
NSC Number:759112|744012
DSSTox ID:DTXSID9046443
NCI Thesaurus Code:C65496
ATC Code:N06AX21
HScode:29349990
Categories:
Characteristics-
PSA:
49.50000
XLogP3:5.82380
Appearance:white to beige
Melting Point:165-171 °C (polymorph)
Boiling Point:466.2ºC at 760 mmHg
Flash Point:9℃
Water Solubility:H2O: soluble5mg/mL (clear solution, warmed)
Storage Conditions:-20°C Freezer
Collision Cross Section:168.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
vitamin
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Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
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Average lead Time:
25
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Less than 5
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Year of Establishment:
2023
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Pakistan
DULOXETINE HCL
2.00 KG Feb 8, 2025 Post an enquiry for this product
