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MOTS-c is a short peptide derived from mitochondria.
MOTS-c is a peptide encoded in mitochondrial DNA. It is believed to be involved in skeletal muscle and glucose metabolism. It is upregulated in response to exercise, and is considered an exercise mimetic. MOTS-c binds to casein kinase 2.
Recently, the positive effects of MOTS-c, one of the mitochondria-derived peptides, on various diseases have been gradually discovered and reported. MOTS-c targets skeletal muscle and can enhance glucose metabolism. Therefore, MOTS-c plays an important role in the regulation of cardiovascular, diabetes, exercise and longevity. It is a new mitochondrial signaling mechanism and plays a role in regulating intracellular and intercellular metabolism. It has been reported that MOTS-c is a kind of exercise-induced mitochondrial coding regulator, and the level of MOTS-c in skeletal muscle and blood of mice decreases with age. Additionally, as an endocrine factor, MOTS-c is likely to exert its effects through cellular entry, which is an ongoing investigation at multiple ends, including its cellular uptake. Understanding the detailed molecular details of MOTS-c is an ongoing endeavor. It was reported that after 30 minutes of treatment, MOTS-c can exert its effects by entering the cells and exerting its effects. There is still a great deal of unclarity as to how MOTS-c enters cells without being degraded and retains its biological activity. A future study of the mechanism by which MOTS-c enters cells will be of great importance in order to determine how it exerts its clinical therapeutic effect. As a potential target for treatment development, MOTS-c is expected to be used in the treatment development of a variety of diseases. Synthetic biology techniques, such as genetic engineering, can greatly improve biological activity and deliver MOTS-c directly to the acting site, thus further expanding the therapeutic application of MOTS-c. However, the subsequent biosafety problem has always been the focus of attention. How to reduce or eliminate the toxicity of genetically engineered bacteria to the body is a key scientific problem to be solved urgently
NOTE: This product was prepared by chemical synthesis. Used only for research. Not for human use.
Key Features
• High-purity grade suitable for research applications
• Structural verification by mass spectrometry and HPLC
• Stable lyophilized form for long-term storage
• Custom modifications available (e.g., labeling, conjugation)
Product Application
1.Helps slow food leaving your stomach.
2.Helps prevent your liver from making too much sugar.
- 3.Helps the pancreas produce more insul when your blood sugar levels are high.
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- 4.Can help control blood glucose.
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- 5.Can reduce hyperglycemia, especially after meals.
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- 6.Can reduce fasting insul and fasting glucose.
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- 7.Can reduce hemoglobin A1c.
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- 8.Can decrease appetite and caloric intake, while inhibiting weight gain.
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- 9.Has been shown to lower triglyceride levels and oxidative stress from high LDL.
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- 10.Can reduce fasting insul and fasting glucose.
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- 11.Has been shown to help induce weight loss in obese patients with higher dosing.
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- 12.Helps decrease leptin and increase leptin sensitivity.
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- 13.Can increase the conversion of white fat to brown fat.
Q: How about the price? Can you make it cheaper?
A: We always take the customer's benefit as the top priority. Price is negotiable under different conditions, we are assuring you to get the most competitive price.
Q. What's the lead time and shipping ways?
A: We will delivery to the package by USPS, FEDEX, DHL paket and other dedicated transportation to you after receive your payment, it would take around 10-15 workdays to your address.
Q: How do i keep the peptides when i receive it ?
A: Peptides in the form of lyophilized powder can be transported at room temperature by vacuum packaging, while polypeptides in the dissolved state need to be refrigerated at 2°C - 8°C. For long-term storage, peptides should be stored in the form of lyophilized powder store at -20°C or -80°C in a sealed container with desiccant, which can avoid the degradation of peptides to the greatest extent.
- MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a small peptide that originates from the mitochondria, the energy-producing organelles within cells. It plays a key role in regulating metabolism, cellular energy production, and age-related health issues. MOTS-C is part of a class of peptides known as mitokines, which are molecules produced by mitochondria that influence cellular functions and systemic processes.
Regulation of Metabolism:
MOTS-C helps regulate glucose metabolism and sensitivity, making it a key player in blood sugar regulation and potentially helpful in managing conditions like type 2 diabetes.
Promotes Fat Loss:
MOTS-C has been shown to enhance fat oxidation, which could support weight loss and prevent excessive fat accumulation, especially in the context of aging or metabolic disorders.
Increases Energy Production:
By boosting mitochondrial function, MOTS-C helps improve cellular energy production, potentially reducing fatigue and increasing overall vitality, particularly in aging individuals.
Anti-Aging Properties:
MOTS-C is thought to have anti-aging effects by improving metabolic health, protecting against oxidative stress, and enhancing the body's ability to handle the stress associated with aging.
Improves Exercise Performance:
Some studies suggest that MOTS-C can enhance physical performance and endurance by increasing the efficiency of energy use within cells, potentially improving athletic performance and recovery.
Supports Muscle Health:
MOTS-C may play a role in maintaining muscle mass and improving muscle function, particularly in older adults, by modulating mitochondrial function and muscle metabolism.
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