we sale full list with peptide products , any other requirements just contact me!
Name:sophia
email: zwxs4@zwxstech.com
WhatsApp: 13791008332
-
-
-
- PNC-27, an anticancer peptide, containing an HDM-2 binding domain corresponding to p53 residues 12-26 and a transmembrane penetrating domain, has been found to kill cancer cells but not normal cells by inducing membrane lysis. The 3D structure of the p53 residue of PNC-27 directly overlaps the structure of the same residue that binds HDM-2, suggesting that this peptide may target HDM-2 in the cell membrane. The researchers found significant levels of HDM-2 in the cell membranes of a variety of cancer cells but not in some untransformed cell lines. In colocalization experiments, PNC-27 bound to cell membrane-bound HDM-2. The researchers used a membrane localization signal to transfect a plasmid expressing full-length HDM-2 into PNC-27-insensitive untransformed MCF-10-2A cells and found that these cells expressed full-length HDM-2 on their cell surface. cells versus PNC-27. We concluded that PNC-27 targets HDM-2 in cancer cell membranes, allowing it to selectively induce membrane lysis in these cells.
-
-
| Product Name | PNC-27 |
| CAS NO. | 1159861-00-3 |
| Purity | 99% |
| Molecular Formula | / |
| MOQ | 1 g
|
Our customers are all over the world, mainly selling in the United States, Canada, Australia, the United. Kingdom, the Ne therlands, Germany, France and other EU countries, Southeast Asia, South America, and Oceania. We also have many customers.
Our business is based on honesty and mutual trust. Sincerely look forward to establishing long-term mutually beneficial business relationships with customers around the world.
Q1:How to send order?
A:Send order list to us,we quote best price for you,then ship package out and offer tracking nubmer to you after payment send.
Q2:Do you have samples for our reference?
A:Sure,we can offer smaples,the customers will pay the freight.
Q3:Any discount if order more?
A:Sure,the price is negotiable,you can get much better price if order big quantity.
Q4:What about the delivery time?
A:Ship within 1-2 days after confirming payment (excluding Chinese holidays).5-7 days to arrive your address.
Q5:What kind of payment terms do you accept?
A:Payment can be made by Bank transfer, BTC,Credite Card,TT,Paypal,Alipay,Wechat,Visa,Mastercard,Appple Pay,Goolge Pay.
Jinan Zhiwen Technology Co., Ltd.The company spirit of "customer first, integrity first principle, with a number of enterprises to establish long-term cooperative relations. Adhere to the quality of survival, creation and development, honest, trustworthy business philosophy, adhere to the "everything quality, customer satisfaction, new, people-oriented quality policy, and constantly improve and perfect themselves. To scientific management, advanced equipment, continuous innovation, to meet the needs of customers. Good reputation and high quality products, has been the majority of domestic and foreign merchants consistent trust. Won the trust of our customers and won the praise of customers!
Company Profile
Our company is a modern advanced enterprise specializing in production and exportation of APIs, Pharmaceutical intermediates, plant extracts etc. Our products are widely used in medicine, health care products, cosmetics, nutritional supplements and food additives areas. Our factory covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Since its establishment, the company has attached great importance to the team training and technical reform. Our modern production equipment guarantees for a fast and effective production with a superior degree of accuracy throughout the whole production line, everything is done in-house, processing, extraction, packaging and transportation of all links, ensuring maximum quality and efficiency. We are constantly research and development new ingredients and innovative new products, have earned the respect & Admiration from the worldwide customers. After years of continuous development, company has been accumulated rich experience in international trade and customer resources, established a stable customer base and perfect marketing service network. In addition, the company has established long-term technical cooperation with experts and professors from many universities and research institutes in the province.
We supply large quantities of peptides.In addition to regular specifications, we can also customize according to customer requirements.
The minimum order quantity is 1 box(10vials), we welcome customers to order samples for testing.Please contact us for COA or HPLC.
We believe that as long as the quality is good enough will lead to long-term cooperation.Looking forward to your inquiry.
United States
