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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Retatrutide for Sale > Pure Retatrutide Peptides Lyophilized Powder CAS 2381089-83-2 Weight loss peptid
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Pure Retatrutide Peptides Lyophilized Powder CAS 2381089-83-2 Weight loss peptid

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Unit Price:

$39/MT FOB

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CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99.99%

Port:

hongkong

Brand:

Yiwu Huangxin Trading Co., Ltd.

Packaging:

5mg/10vials 10mg/10vials

Price valid (until):

2026-08-30

The product will be displayed normally on the website later.
Company Type:
Trader
Location:
China
Qualification:
Main Products:

Polypeptide product

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.

    Contact Us

    Yiwu Huangxin Technology Co., Ltd.

    WS:+852  4424  8557

    huangxin5188@qq.com

    Retatrutide Product Detailed Description / Retatrutide   


    Welcome to Yiwu Huangxin Trading Co., Ltd., your premier and reliable partner for high-purity research peptides. We specialize in providing top-tier biological reagents and chemical raw materials to global laboratories, pharmaceutical research institutions, and wholesale distributors.Our flagship product, Retatrutide (CAS 2381089-83-2), is manufactured under strict cGMP guidelines to ensure the highest standards of purity, stability, and biological activity. Retatrutide is a pioneering synthetic peptide containing 39 amino acids. It represents the next generation of metabolic research compounds, acting as a triple agonist against the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon (GCG) receptors.

    Items Specifications
    Product Name Retatrutide
    Molecular Formula C221H342N46O68
    Purity (HPLC) ≥ 99.0% (Premium Grade)
    Storage Temperature Store at -20°C for long term; 2-8°C for short term stability
    Application Laboratory research use, metabolic disease studies, chemical intermediates
    Shop Retatrutide Factory Supply Retatrutide 5mg 10mg Vials Lyophilized Powder High Quality, Worldwide Shipping-Detailed Image 1
    Shop Retatrutide Factory Supply Retatrutide 5mg 10mg Vials Lyophilized Powder High Quality, Worldwide Shipping-Detailed Image 2


      Functions, Mechanisms, and Applications 


    A. Triple Receptor Agonism (GLP-1 / GIP / Glucagon)
    Retatrutide distinguishes itself from traditional single or dual agonists (such as Semaglutide or Tirzepatide) by targeting three distinct metabolic pathways simultaneously:
    • GIP Receptor Activation: Enhances insulin secretion in response to glucose, improves lipid clearance, and significantly dampens metabolic inflammation.
    • GLP-1 Receptor Activation: Delays gastric emptying, suppresses appetite centrally via the hypothalamus, and optimizes glycemic control.
    • Glucagon (GCG) Receptor Activation: Increases energy expenditure, stimulates lipolysis in adipose tissue, and accelerates fatty acid oxidation in the liver.
    B. Core Research Applications
    1. Obesity and Weight Regulation Studies: In animal models and clinical research environments, Retatrutide demonstrates unprecedented efficacy in reducing adipose tissue and reducing overall body mass by accelerating metabolic rates.
    2. Type 2 Diabetes & Insulin Sensitivity: It assists in researching glucose homeostasis, lowering HbA1c levels, and reversing insulin resistance in pancreatic beta-cell studies.
    3. Non-Alcoholic Fatty Liver Disease (NAFLD/NASH): The inclusion of the glucagon receptor mechanism allows researchers to study the drastic reduction of liver fat accumulation and systemic fibrosis.
    4. Cardiovascular Health & Lipid Profiles: Researchers utilize this compound to study improvements in blood pressure, triglyceride reduction, and overall cardiovascular metabolic markers.

    Shop Retatrutide Factory Supply Retatrutide 5mg 10mg Vials Lyophilized Powder High Quality, Worldwide Shipping-Detailed Image 3
    Shop Retatrutide Factory Supply Retatrutide 5mg 10mg Vials Lyophilized Powder High Quality, Worldwide Shipping-Detailed Image 4


      Product Advantages & Quality Control  


    Why choose Retatrutide from Yiwu Huangxin Trading Co., Ltd.? We enforce rigorous scientific testing for every batch we export.
    • Ultra-High Purity: Our Retatrutide maintains a strict HPLC purity profile of over 99.0%, ensuring no interference from truncated peptide impurities during sensitive bioassays.
    • Perfect Lyophilization Technology: We utilize advanced vacuum freeze-drying techniques. The resulting cake has excellent solubility, rapid reconstitution, and long shelf-life stability.
    • Batch Consistency: Every single batch undergoes High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) testing to verify exact molecular weight and sequence identity. COA (Certificate of Analysis) is provided with every shipment.
    • Zero Contamination: Our synthesis and packaging are conducted in Class 100,000 cleanrooms, minimizing endotoxin levels to meet global laboratory research prerequisites.

    Shop Retatrutide Factory Supply Retatrutide 5mg 10mg Vials Lyophilized Powder High Quality, Worldwide Shipping-Detailed Image 5
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    Shop Retatrutide Factory Supply Retatrutide 5mg 10mg Vials Lyophilized Powder High Quality, Worldwide Shipping-Detailed Image 7


      Company Introduction  


    Yiwu Huangxin Trading Co., Ltd. is a prominent and internationally active enterprise based in Yiwu City, Zhejiang Province, China—the world's largest capital of international trade and logistics. We are a specialized supplier dedicated to the procurement, quality evaluation, and international distribution of advanced pharmaceutical intermediates, biochemical reagents, and cosmetic peptide raw materials.
    Leveraging Yiwu’s unparalleled logistical ecosystem and our deep partnerships with top-tier domestic chemical synthesis laboratories, Yiwu Huangxin Trading Co., Ltd. has successfully bridged the gap between high-end chemical manufacturing and global client demand.
    Our team comprises experienced foreign trade professionals, quality assurance chemists, and logistics experts. We do not just sell chemicals; we deliver supply chain security. We strictly implement standard operating procedures (SOPs) for product verification, temperature-controlled warehousing, and compliant border clearance. Over the years, we have built a flawless reputation across North America, Europe, Australia, and Southeast Asia. We support flexible business models, including custom packaging, OEM vial labeling, and small-batch sample testing to accommodate both academic researchers and large-scale industrial buyers.

    Shop Retatrutide Factory Supply Retatrutide 5mg 10mg Vials Lyophilized Powder High Quality, Worldwide Shipping-Detailed Image 8
    Shop Retatrutide Factory Supply Retatrutide 5mg 10mg Vials Lyophilized Powder High Quality, Worldwide Shipping-Detailed Image 9


    Shipping, Packaging & Global Customs Logistics   


    International chemical logistics requires specialized expertise. Yiwu Huangxin Trading Co., Ltd. has engineered a worry-free delivery network to safeguard your investment.
    • Packaging Integrity: Standard packaging consists of heavy-duty, temperature-insulated foil bags with ice gel packs if required. For bulk orders, double-layered anti-static bags inside secure, discreet drums are used.
    • Discreet and Blind Shipping: We employ specialized, covert packaging options to guarantee smooth clearance through international customs frameworks without unnecessary delays.
    • Guaranteed Customs Clearance: We offer a 100% reshipment policy or alternative route routing for key destinations including the USA, UK, Canada, Germany, France, Netherlands, and Australia if any logistical customs disruption occurs.
    • Rapid Delivery Carriers: We partner with DHL, FedEx, UPS, EMS, and dedicated local air cargo lines to ensure door-to-door delivery within 5 to 12 business days globally. Tracking numbers are updated within 24 hours of dispatch.

    Shop Retatrutide Factory Supply Retatrutide 5mg 10mg Vials Lyophilized Powder High Quality, Worldwide Shipping-Detailed Image 10
    Shop Retatrutide Factory Supply Retatrutide 5mg 10mg Vials Lyophilized Powder High Quality, Worldwide Shipping-Detailed Image 11

    Certificates
    • Pure Retatrutide Peptides Lyophilized Powder CAS 2381089-83-2 Weight loss peptid Certificates 1 TDS

    Basic Info
    Product Name:

    Retatrutide

    Other Name:

    Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

    CAS No.:

    2381089-83-2

    Molecular Formula:

    C221H342N46O68

    Molecular Weight:

    4731.33

    EC Number:

    200-001-8

    Color/Form:

    White lyophilized

    Characteristics
    Water Solubility:

    Soluble in water (5mg/ml).

    Storage Conditions:

    -20°C

    Critical Temperature & Pressure:

    -20°C

    Research
    Class:

    Triple agonist — GCGR, GIPR, GLP-1R

    Status:

    Investigational (Phase 3)

    Mechanism:

    Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

    EC50 (Human GCGR):

    5.79 nM

    EC50 (Mouse GIPR):

    0.191 nM

    EC50 (Mouse GLP1R):

    0.794 nM

    EC50 (Mouse GCGR):

    2.32 nM

    EC50 (Human GLP1R):

    0.775 nM

    EC50 (Human GIPR):

    0.0643 nM

    Source:

    Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

    Clinical Development:

    NCT04881760; NCT05882045; NCT06354660

    References
    ChEMBL:

    CHEMBL5095485

    DrugBank:

    DB18993

    KEGG DRUG:

    D12430

    PubChem:

    PubChem

    Disclaimer:

    Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Polypeptide product

    Location:

    Unit 2, Building 141, Lane 23, Dongliantang Village, Yiwu City, Jinhua City, Zhejiang Province, Room 305

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    366

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    11-50

    Year of Establishment:

    2026

  • Inquiry History
    6441 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Retatrutide 2381089-83-2

    3 MT Mar 28, 2026
    United Kingdom

    Retatrutide - 2381089-83-2

    1 G Feb 10, 2026
    United States

    Retatrutide CAS 2381089-83-2 10mg vial

    20 MT Mar 7, 2026
    United States

    Factory Retatrutide API 99% Purity CAS 2381089-83-2

    5 KG Nov 10, 2025
    United Kingdom

    Peptide powder Retatrutide 99% pure for Body building cas 2381089-83-2 Weight Loss Peptide with COA

    1 MT Mar 22, 2026
    United States

    2381089-83-2

    100 G Jul 14, 2026
    United States

    2381089-83-2

    100 G Feb 24, 2026
    United States

    2381089-83-2

    100 MT Dec 9, 2023
    United States

    Retatrutide 2381089-83-2

    200 MG May 16, 2026
    United Kingdom

    2381089-83-2 retatrutide

    300 MG Feb 13, 2026
    United States

    Retatrutide 2381089-83-2 wholesale

    500 MT Nov 3, 2023
    United States

    Retatrutide CAS 2381089-83-2 99%

    10 PCS Feb 21, 2026
    Poland

    CAS 2381089-83-2 (Custom Peptide)

    40 MT Apr 10, 2026
    Austria

    Peptide Retatruide CAS 2381089-83-2

    100 MT Apr 4, 2026
    Austria

    Retatrutide CAS 2381089-83-2 10mg vial

    20 PCS Feb 10, 2026
    United States

    Tirzepatide 99.9% Liquid 2381089-83-2 TeruiOP

    1 MT Sep 6, 2023
    United States

    Retatrutide/LY3437943/GIPR/GLP-1R 98% Powder 2381089-83-2 Senwayer

    1 G Sep 3, 2023
    United States

    GLP-1 / GIP Retatrutide cas 2381089-83-2

    1 MT Oct 16, 2024
    United States

    Retatrutide 99% High Quality CAS 2381089-83-2

    1 G Jan 23, 2026
    United States

    Injection Peptide Tirzepatide/Retatrutide/ Semaglutide Peptides CAS 2381089-83-2

    10  Oct 21, 2023
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