GHK-Cu Copper Peptide Lyophilized Powder For Laboratory Research Only

Description 

                                                                                                Name: Tina
                                                       WhatsApp: +852 9843 7019

GHK-Cu is a versatile peptide with significant roles in promoting tissue repair, reducing inflammation, and enhancing skin health.
Mechanism of Action
GHK-Cu exerts its effects primarily through its interaction with fibroblasts and other cells involved in tissue repair. The peptide enhances the production of several key proteins and molecules:
Collagen and Elastin Production: GHK-Cu stimulates the synthesis of collagen, elastin, and glycosaminoglycans, which are essential for maintaining skin structure and elasticity.
Gene Regulation: It influences gene expression by modulating the activity of various transcription factors. This includes upregulating genes associated with wound healing, angiogenesis (formation of new blood vessels), and anti-inflammatory responses.
Antioxidant Activity: GHK-Cu acts as an antioxidant, reducing oxidative stress by scavenging free radicals and promoting the activity of antioxidant enzymes like superoxide dismutase (SOD).

Applications:
GHK-Cu has a wide range of applications in both cosmetic and therapeutic contexts:
Skin Health: It is commonly used in skincare products to improve skin elasticity, reduce wrinkles, and enhance overall skin appearance by promoting collagen synthesis and wound healing.
Wound Healing: GHK-Cu accelerates the healing process for various types of wounds by enhancing tissue repair mechanisms and reducing inflammation.
Hair Growth: The peptide has been shown to stimulate hair follicle activity, potentially reversing hair thinning and promoting hair growth.
Anti-Aging Treatments: Its ability to remodel aged skin makes it a popular ingredient in anti-aging formulations.

 In studies on the affinity of GHK for copper, where the histidine residue was replaced by a synthetic amino acid, it was shown that the glycine residue plays an essential role in copper binding, while the lysine residue can interact with copper only in basal. At physiological pH, lysine can interact with a cell receptor. Thanks to GHK's ability to interact with both copper and a cellular receptor, it can transport copper in and out of cells. The small size of the GHK molecule allows it to circulate rapidly in the extracellular space and easily access cellular receptors

    The structure of the GHK-Cu complex has been studied in detail by X-ray crystallography, electron paramagnetic resonance, X-ray absorption spectrometry, NMR spectroscopy or even by titration. In this complex, the Cu2+ cation is coordinated to the imidazole of the side chain of the histidine residue, and to the atom of the deprotonated peptide bond between glycine and histidine residues. Insofar as such a structure does not explain the great stability of this complex, whose decimal logarithm of the dissociation constant is worth log10(K) = 16.44, against 8.68 for the GH-Cu complex, which is similar in structure to the GHK-Cu complex, it has been suggested that another GHK atom is involved in stabilizing the complex with copper. It could be the carboxylic oxygen atom of the lysine4 residue.

    Many researchers have proposed that GHK-Cu complexes form dimers and trimers at physiological pH which may include a histidine residue and/or the copper binding region of the albumin molecule. The dissociation constant of the complex formed with copper is log10(K)=16.2 with plasma albumin versus 16.44 with GHK.

1.How to confirm the product quality before placing an order?
A: We can provide you with the sample. Also, we have the inspection report issued by the authoritative third-party testing agency.

2: What's your MOQ?
A: It depends on different products. We accept sample orders. Also for some products, we can provide you with a sample.

3:Do you provide after-sales service?
A: We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us.

4:How about delivery time and method?
A: We usually ship within 3-5 working days after payments. We can make ships by sea, air, and express. Also can make door-to-door shipping.

5:How to solve the after-sale disputes?
A: We accept changing or refunding services if there is any quality problem.

How to proceed your order:

Step 1: Contact us: add our WhatsApp or contact supplier or chat now.

Step 2: Tell us what you want.

Step 3: We quote you.

Step 4: You confirm the order and pay it.

Step5: We arrange the shipment then give you tracking number.

Step 6: We offer after-sales services.