Pirtobrutinib CAS 2101700-15-4 Highly Selective Non-Covalent BTK Inhibitor for B-Cell Malignancies Research kr
TDS
2101700-15-4
Reagent Grade
99%
qingdao
//
1mg, 5mg, 10mg, 25mg, 50mg, 100mg
2026-09-01
Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524
-
Product Description
-
Seller Information
-
DescriptionECHEMI Editorial ReferencePirtobrutinib is an orally available, selective, non-covalent Bruton's tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. Upon oral administration, pirtobrutinib selectively and reversibly binds to BTK. This prevents both the activation of the B-cell antigen receptor (BCR) signaling pathway and BTK-mediated activation of downstream survival pathways, thereby inhibiting the growth of malignant B-cells that overexpress BTK. Reversible binding of LOXO-305 may preserve antitumor activity in the presence of certain acquired resistance mutations, including C481 mutated BTK, and limit toxicity associated with inhibition of other non-BTK kinases. BTK, a member of the Src-related BTK/Tec family of cytoplasmic tyrosine kinases, is overexpressed or mutated in B-cell malignancies; it plays an important role in the development, activation, signaling, proliferation and survival of B-lymphocytes.Certificates
-
TDS
Basic Info-
Product Name:
Pirtobrutinib
Other Name:Pirtobrutinib;BTK inhibitor 16;LOXO-305;LY3527727;2101700-15-4;(S)-5-Amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4-carboxamide;Pirtobrutinib [USAN];UNII-JNA39I7ZVB;JNA39I7ZVB;LOXO305
CAS No.:2101700-15-4
Molecular Formula:C22H21F4N5O3
InChIKeys:FWZAWAUZXYCBKZ-NSHDSACASA-N
Exact Mass:479.15805220
NCI Thesaurus Code:C158617
Categories:
-
-
Seller Information
-
Business Type:
Trader
-
Main Products:
Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524
-
Location:
RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA
-
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
-
Average lead Time:
7
-
Total Annual Revenue:
$1 million-$2.5 million
-
Total Employees:
11-50
-
Year of Establishment:
2022
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product