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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Sermorelin Acetate for Sale > Sermorlin Acetate / 99% Purity/ 10mg SMO10/ Growth-promoting peptide
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Sermorlin Acetate / 99% Purity/ 10mg SMO10/ Growth-promoting peptide

2 Inquiries

Unit Price:

$88/UNIT FOB

Get Latest Price
CAS No.:

114466-38-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

HongKong

Brand:

HUATAI

Packaging:

10 vials/kit

Price valid (until):

2026-09-04

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Tirzepatide,Retatrutide,NAD+,Samaglutide,GHK-CU,cagrilintide

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Description   


    Sales manager: Amy
    whatsapp: +85244962136
    Email:  xuguangqing97@hotmail.com

    Items Specifications
    Name Sermorlin-acetate
    Grade Pharmacy Grade
    Content 99.9%
    CAS No 114466 - 38 - 5
    Packaging  5mg 10mg/vial, 10vials/box

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      Product Detail  


       

           It (also known by its INN names Geref/Gerel, or GHRH 1-29) is a peptide analogue of growth hormone-releasing hormone (GHRH). It is used as a diagnostic agent to evaluate growth hormone (GH) secretion and to diagnose growth hormone deficiency. It is a 29-amino-acid peptide representing the 1-29 fragment of endogenous human GHRH and is considered the shortest fully functional fragment of GHRH.
           SMO essentially mimics the hypothalamic peptide GHRH and acts directly on the pituitary gland to stimulate the capacity of somatotrophs (growth hormone cells) to produce and secrete GH. It influences the synergistic hormonal signaling of the GH axis. GH secretion from the anterior pituitary is regulated by growth hormone-releasing hormone, somatostatin, and GH secretagogues. The positive and negative regulation of GH by GHRH and somatostatin generates the rhythmic circadian secretion of GH. GH signaling targets cells to increase the synthesis of IGF-1, most notably in the liver and peripheral tissues.
    Structure and Nature
    • Synthetic Fragment: It is the first 29 amino acid fragment of natural growth hormone-releasing hormone (GHRH).
    • Acetate Form: The "Acetate" in its chemical name indicates that it exists in acetate salt form, which enhances the peptide's solubility in water and its chemical stability.
    Core Mechanism of Action
    • Indirect Growth Promotion: Unlike direct administration of recombinant human growth hormone (such as PEG-MGF mentioned previously), Sermorelin does not act directly on target organs. Instead, it acts as a "command signal."
    • Pituitary Activation: Once in the body, it specifically binds to and activates receptors in the anterior pituitary, prompting the pituitary to autonomously secrete endogenous growth hormone in accordance with the body's natural circadian rhythm.
    Primary Clinical Applications
    • Pediatric Growth Assessment: Clinically, it has been used to diagnose and treat pediatric growth hormone deficiency, helping to evaluate the pituitary's GH reserve capacity.
    • Anti-Aging and Sports Recovery: In some overseas anti-aging medicine and sports rehabilitation fields, it is used to improve sleep quality, promote muscle repair, increase collagen synthesis, and assist in fat loss.

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     The common problems


    Q1: May I get one sample before placing order?

    Re: Yes, Sample are available. For normal products, samples are for free and you just need to bear the freight; For those high value products, you just need to freight and certain product cost. When we both cooperate for some times or when you are our VIP customer, free sample will be offered when you need.

    Q2: Which payment is available for your company?

    Re: T/T, PayPal,bank transfer etc. You can choose the one which is convenient for you.

    Q3: How and when can I get my goods after payment?

    Re: For small quantity products, they will be delivered to you by international courier(DHL, FedEx, TNT etc.) or by air. Usually it will cost 5-7days that you can get the goods after delivery.For large quantity products, shipping by see is worthwhile.It will cost 15 to 30 days to come to your destination port, which depends on where the port is.

    Q4: Is there any possible to use my appointed label or package?

    Re: Yes. If needed, we'd lik

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    Why choose us?


    1.Higher quality products (>=99% purity) for most of peptides and raws., adequate stock and fast delivery competitive price.

    2. Ship worldwide with safe and secure lines: 

    3. Special Service: Drop-shipping if need.

    4. Cheapest prices in the market, unbeatable!

    5. Many payment options:Wise, Bank Transfer, Alipay,alibaba

    6.Safe and fast delivery
    Shop Sermorlin Acetate / 99% Purity/ 10mg  SMO10/  Growth-promoting peptide-Detailed Image 6


      Company Profile  


    Our company is located in Zhejiang Province and is a Chinese enterprise specializing in the production of peptide products.We are not intermediaries or resellers; we are the original manufacturer. This allows us to offer you the most competitive pricing. Our motto is: to manufacture products with care and serve customers with dedication.We are dedicated to serving every visitor with heart. No matter where you come from, you will experience our premium VIP service. We guarantee that every customer receives only the finest products, backed by exceptional after-sales support, as we strive to ensure your complete satisfaction.

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      Packing process  


    Shop Sermorlin Acetate / 99% Purity/ 10mg  SMO10/  Growth-promoting peptide-Detailed Image 11

    If you need any assistance, please feel free to contact us at any time!

    Sales manager:  Amy
    whatsapp:+85244962136
    Email:  xuguangqing97@hotmail.com

    Basic Info
    Product Name:

    Sermorelin Acetate

    CAS No.:

    114466-38-5

    Molecular Formula:

    C149H246N44O42S

    InChIKeys:

    BVLCEKWPOSAKSZ-YQMCHIOTSA-N

    Molecular Weight:

    3417.9 g/mol

    Exact Mass:

    3416.843184 g/mol

    Characteristics
    PSA:

    1510 Ų

    XLogP3:

    5.07090

    Research
    Class:

    GHRH analog (1–29 amino-terminal fragment, 29-amino-acid peptide amide)

    Status:

    FDA-approved diagnostic agent (Geref, discontinued). NOT for therapeutic use.

    Mechanism:

    A synthetic 29-amino-acid peptide (H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂) identical to the amino-terminal segment of endogenous human GHRH. Sermorelin binds to the GHRH receptor (GHRHR) on anterior pituitary somatotrophs, stimulating pulsatile GH synthesis and secretion via the cAMP/PKA pathway. Unlike exogenous GH, sermorelin preserves the endogenous GH pulsatility and IGF-1 feedback loop.

    EC50 (Ghrhr Ec50):

    ~0.1–1 nM (cAMP accumulation in rat pituitary cells)

    Source:

    DrugBank: DB00010. Frohman LA, et al. Endocr Rev. 1986;7(3):223–253.DOI

    Clinical Development:

    NCT00001390; NCT00527397

    FDA:

    Geref (approved 1991-10-11)

    References
    ChEMBL:

    CHEMBL1201555

    DrugBank:

    DB00010

    KEGG DRUG:

    D08554

    PubChem:

    PubChem

    Disclaimer:

    Sermorelin was FDA-approved as a diagnostic agent (Geref) for growth hormone deficiency but has been discontinued (not for safety reasons). It is NOT approved for anti-aging, bodybuilding, or therapeutic GH replacement. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Tirzepatide,Retatrutide,NAD+,Samaglutide,GHK-CU,cagrilintide

    Location:

    1502A1, Building 4, Xinyuanxin Center, No. 3 Huaxin Road, Dongfeng Street, Licheng District, Jinan City, Shandong Province

    Payment Terms:

    TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    1

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    51-100

    Year of Establishment:

    2026

    Certifications:

    COA,COA,COA,COA,COA,COA,COA,COA,COA,COA,COA,COA

    COMPANY INTRODUCTION

    20 years of dedicated work in the peptide industry

    15 Years of Industry Experience

    We have been a high-tech company focused on the development, production, and marketing of various peptide products

     for 15 years. Through advanced laboratories and strict quality control, our internationally certified products are safe and 

    effective.


    Clients in Europe, the USA, Southeast Asia, and the Middle East

    As a global trading company, we serve clients across Europe, the USA, Southeast Asia, the Middle East, and beyond, providing

     customized solutions. Committed to "technology leading Health", we aim to innovate and deliver high-quality health products 

    worldwide.


    3,000sqm Factory with 60 Employees

    We have a factory covering 3,000 square meters and housing 60 employees to guarantee the highest quality all the time. We hired 

    three quality auditors with three years of experience. They meticulously inspect each item at every production stage.


    Contact Us Now

    Our products are exported to more than 130 countries and regions, which can be delivered fast within 5-14 days. We can provide

     OEM/ODM support to our customers. We have 10 professional after-sales staff to make 24-hour responses to our customers. 

    Contact us now to learn more. We hope to establish stable and strategic long-term business relationships with domestic and 

    foreign suppliers and customers, jointly pursuing a better future.


  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Sermorelin acetate HGRH

    1 KG Nov 25, 2025
    South Korea

    Sermorlin Acetate

    10  Jul 25, 2025
    Post an enquiry for this product
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