Adipotide/ 99% purity / 2mg 5mg AP2 AP5/ Fat loss

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I. Basic Information

• English Name: Adipotide; FTPP (Fat-Targeting Pro-apoptotic Peptide); Pro-Apo Fat peptide
• Chinese Name: Fat-Targeting Apoptotic Peptide; Lipolytic Peptide; Weight-Loss Peptide; Vascular-Targeted Lipid-Reducing Peptide
• Full Structural Formula: CKGGRAKDC-GG-D(KLAKLAK)₂
• II. Physicochemical Parameters

• Exact Mass: 2415.95 Da
• Molecular Formula: C₁₀₃H₁₈₇N₃₃O₂₉S₂
• Theoretical Isoelectric Point (pI): ≈ 9.8 (Strongly basic peptide)
• Appearance: White or off-white powder
• Solubility: Highly soluble in water, PBS, and normal saline
• Stability:
  • * Powder: Store at −20 °C in a dry, light-protected environment for long-term preservation.
  • * Solution: Store at 4 °C for short-term use. Freshly prepare before use and avoid repeated freeze-thaw cycles.

1. Precise Targeting
   •  *Enters the bloodstream.
   •  *Specifically binds to Annexin A2 on the vascular endothelial cells of adipose tissue.
   •  *Exhibits minimal accumulation in muscles, heart, brain, liver, and kidneys.
   •  *Demonstrates high organ selectivity.
2. Cellular Internalization
   •  *Endocytosed into the cell upon receptor binding.
   •  *The intact peptide chain enters the cytoplasm.
3. Mitochondrial Damage & Apoptosis Initiation
   •  *The C-terminal KLAK domain targets the mitochondria.
   •  *Inserts into the inner mitochondrial membrane → increases membrane permeability.
   •  *Collapse of membrane potential → release of Cytochrome C.
   •   *Activates the Caspase cascade → induces apoptosis in vascular endothelial cells.
4. Adipose Tissue Microvascular Degeneration
   •  *Massive apoptosis of adipose vasculature → collapse of the microvascular network.
   •  *Adipose tissue experiences ischemia, hypoxia, and nutrient deprivation.
   •  *Adipocytes cannot survive → triggering secondary apoptosis and lipolysis.
   •  *Results in reduced fat volume, decreased fat cell count, and attenuated inflammation.
5. Systemic Metabolic Improvement
   •  *Significant reduction in visceral fat.
   •  *Enhanced insulin sensitivity.
   •  *Improvement in blood glucose, blood lipids, and fatty liver.
   •  *Stable weight loss without rebound or muscle wasting.

1. Potent Lipid Reduction (Core Function)
   •  *Preferentially reduces: White adipose tissue, visceral fat, and abdominal fat.
   •  *No effect on: Central nervous system, heart, and skeletal muscle.
   •  *Does not cause: Fatigue, palpitations, diarrhea, or anorexia.
2. Improvement of Metabolic Diseases
   •  *Type 2 Diabetes: Ameliorates insulin resistance.
   •  *Metabolic Syndrome: Lowers blood glucose and lipids.
   •  *Non-Alcoholic Fatty Liver Disease (NAFLD): Alleviates hepatic steatosis (fat infiltration).
3. Anti-Inflammatory Effects
   •  *Chronic inflammation in adipose tissue is the root cause of metabolic diseases.
   •  *Adipotide reduces macrophage infiltration in adipose tissue.
   •  *Decreases inflammatory cytokines: TNF-α, IL-6, and MCP-1.
4. Potential in Tumor Research
   •  *Annexin A2 is also highly expressed in certain tumor vasculatures.
   •  *Can serve as a vascular-targeting carrier for tumors.
   •  *Applied in precision-targeted therapy research for solid tumors.
5. Anti-Aging & Weight Management
   •  *Reduces age-related visceral fat accumulation.
   •  *Improves metabolic aging phenotypes.
   •  *Enhances insulin sensitivity and extends healthspan.

•       For long-term storage, peptides should be kept in lyophilized powder form at a low temperature of -20°C or -80°C, strictly maintained in a dry, airtight, and light-protected environment. Under these conditions, most lyophilized peptides can remain stable for several years.
•       Peptides in solution are significantly less stable than in lyophilized powder form and are highly susceptible to bacterial degradation; therefore, long-term storage in solution is not recommended. Aqueous solutions should ideally be stored at 4°C for short-term use (typically no longer than 24 hours), and it is best to prepare them fresh right before use. If frozen storage is required after dissolution, the peptide must be aliquoted into small tubes. Thaw and use only one tube at a time; any remaining solution should be discarded immediately. Never mix fresh and used solutions, and strictly avoid repeated freeze-thaw cycles.

1. How to make an order?
Send me message and let me know what you need with quantity, then i will calculate to you.

2. What's the lead time and shipping ways?
We will delivery to the package by UPS, FEDEX, DHL paket and YANWEN express to you after receive your payment, it would take 10-15 days. We will also track the logistics throughout the entire process and update the logistics information for buyers in real time.

3.  What's the payment methods?
We could accept pay through Alipay, USDT, BTC and TT.

4.Does the product have a test report?
Each batch of our products undergoes testing before leaving the factory, and a Certificate of Analysis (COA) report is issued.

      Our company is located in Zhejiang Province and is a Chinese enterprise specializing in the production of peptide products.We are not intermediaries or resellers; we are the original manufacturer. This allows us to offer you the most competitive pricing. Our motto is: to manufacture products with care and serve customers with dedication.We are dedicated to serving every visitor with heart. No matter where you come from, you will experience our premium VIP service. We guarantee that every customer receives only the finest products, backed by exceptional after-sales support, as we strive to ensure your complete satisfaction.