emtricitabine CAS.143491-57-0
143491-57-0
Pharmaceutical Grade
99%
Shenzhen
Flying
10g/1kg/ 10kg/ 25kg
2026-09-06
vitamin
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceWhite to Off-White Crystalline SolidChEBI: An organofluorine compound that is 5-fluorocytosine substituted at the 1 position by a 2-(hydroxymethyl)-1,3-oxathiolan-5-yl group (2R,5S configuration). It is used in combination therapy for the treatment of HIV-1 infect on.Emtricitabine is a nucleoside reverse transcriptaseinhibitor (NRTI) which has been marketed for the prevention and treatment of HIV infection. It also exhibits clinical activity against the hepatitis B virus (HBV) (not yet approv
Solid
Emtricitabine is an organofluorine compound that is 5-fluorocytosine substituted at the 1 position by a 2-(hydroxymethyl)-1,3-oxathiolan-5-yl group (2R,5S configuration). It is used in combination therapy for the treatment of HIV-1 infection. It has a role as an antiviral drug and a HIV-1 reverse transcriptase inhibitor. It is a pyrimidone, an organofluorine compound, a monothioacetal and a nucleoside analogue.|Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with [tenofovir alafenamide] for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of HIV RNA to DNA. Emtricitabine was granted FDA approval on 2 July 2003.|Emtricitabine is a Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of emtricitabine is as a Nucleoside Reverse Transcriptase Inhibitor.|Emtricitabine is a nucleoside analogue and reverse transcriptase inhibitor used in combination with other agents for treatment and prevention of human immunodeficiency virus (HIV) infection and the acquired immunodeficiency syndrome (AIDS). Emtricitabine does not appear to be a significant cause of drug induced liver injury, but may cause flares of disease in patients with underlying chronic hepatitis B virus (HBV) infection.|Emtricitabine is a synthetic fluoro derivative of thiacytidine with potent antiviral activity. Emtricitabine is phosphorylated to form emtricitabine 5'-triphosphate within the cell. This metabolite inhibits the activity of human immunodeficiency virus (HIV) reverse transcriptase both by competing with the natural substrate deoxycytidine 5'-triphosphate and by incorporation into viral DNA causing a termination of DNA chain elongation (due to the lack of the essential 3'-OH group).|A deoxycytidine analog and REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B viruses. It is used to treat HIV INFECTIONS.Basic Info-
Product Name:
Emtricitabine
Other Name:2(1H)-Pyrimidinone,4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-;2(1H)-Pyrimidinone,4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,(2R-cis)-;1,3-Oxathiolane,2(1H)-pyrimidinone deriv.;4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone;(-)-FTC;FTC,(-)-;(-)-2′-Deoxy-5-fluoro-3′-thiacytidine;524W91;BW 524W91;Emtricitabine;Coviracil;BW 1592;Emtriva;(-)-2′,3′-Dideoxy-5-fluoro-3′-thiacytidine;(-)-Emtricitabine
CAS No.:143491-57-0
Molecular Formula:C8H10FN3O3S
InChIKeys:InChIKey=XQSPYNMVSIKCOC-NTSWFWBYSA-N
Molecular Weight:247.24700
Exact Mass:247.25
EC Number:604-363-1
UNII:G70B4ETF4S
DSSTox ID:DTXSID0040129
NCI Thesaurus Code:C47509
Color/Form:White to off white powder|White solid from ether and methanol
ATC Code:J05AR03|J05AR06|J05AR|J05AR17|J05AR19|J05|J05AF09|J05AR08|J05AR09|J - Antiinfectives for systemic use
HScode:2934999090
Categories:
Characteristics-
PSA:
115.67000
XLogP3:-0.6
Density:1.82 g/cm3
Melting Point:136-140ºC
Boiling Point:443.3ºC at 760 mmHg
Flash Point:221.9ºC
Refractive Index:1.731
Water Solubility:2.00e+00 g/L
Storage Conditions:Store at 25 deg C (77 deg F); excursions permitted to 15 deg C-30 deg C (59 deg F-86 deg F)
Vapor Pressure:0mmHg at 25°C
Henrys Law Constant:Henry's Law constant = 1.08X10-17 atm-cu m/mole at 25 °C (est)
Dissociation Constants:2.65|pKa = 2.65 (amine)
Experimental Properties:Hydroxy radical reaction rate constant = 1.34X10-10 cu cm/molec-sec at 25 °C (est)|Ozone reaction rate constant = 7.0X10-19 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
vitamin
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Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
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Average lead Time:
25
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Less than 5
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Year of Establishment:
2023
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