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API Emtricitabine

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CAS No.:

143491-57-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Price valid (until):

2025-05-21

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Description

    Name

    Emtricitabine

    CAS number

    143491-57-0

    Synonym

    Emtricitabine; 2-FTC; 524W91; BW 1592; BW-1592; BW1592; BW 524W91; BW-524W91; BW524W91; Coviracil; dOTFC; DRG-0208; DRG 0208; DRG0208; Emtriva.

    Description

    Emtricitabine is a nucleoside analogue which inhibits the reverse nucleoside transcriptase enzyme. Structurally this antiviral agent is similar to Lamivudine. This agent is effective at targeting HIV and HBV viruses since these viruses replicate in a reverse transcriptase manner. Studies indicate that the structure of Emtricitabine, specifically the unnatural β-L structural configuration produce greater antiviral effects in vitro on HIV and HBV than other antiviral agents.

    Molecular Formula

    C8H10FN3O3S

    Molecular Weight

    247.250

    Appearance

    Solid powder

    Quality Standard

    USP, EP, BP, CP

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Dry, dark and at 0 – 4 for short term (days to weeks) or -20 for long term (months to years).

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China


    Emtricitabine More Info

    Emtricitabine, with trade name Emtriva (formerly Coviracil), is a nucleoside reverse-transcriptase inhibitor (NRTI) for the prevention and treatment of HIV infection in adults and children. In 2019, it was the 494th most commonly prescribed medication in the United States, with more than 3 thousand prescriptions.

     

    Emtricitabine makes up one fourth of the Quad pill (brand names: Stribild and Genvoya). It is also marketed in a fixed-dose combination with tenofovir disoproxil (Viread) under the brand name Truvada, and with tenofovir alafenamide (Vemlidy) under the brand name Descovy. In fixed-dose combinations with tenofovir or with efavirenz and tenofovir it is on the World Health Organization's List of Essential Medicines. A fixed-dose triple combination of emtricitabine, tenofovir and efavirenz (Sustiva, marketed by Bristol-Myers Squibb) was approved by the U.S. Food and Drug Administration (FDA) on July 12, 2006, under the brand name Atripla.


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    Certificates

    Basic Info
    Product Name:

    Emtricitabine

    Other Name:

    2(1H)-Pyrimidinone,4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-;2(1H)-Pyrimidinone,4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,(2R-cis)-;1,3-Oxathiolane,2(1H)-pyrimidinone deriv.;4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone;(-)-FTC;FTC,(-)-;(-)-2′-Deoxy-5-fluoro-3′-thiacytidine;524W91;BW 524W91;Emtricitabine;Coviracil;BW 1592;Emtriva;(-)-2′,3′-Dideoxy-5-fluoro-3′-thiacytidine;(-)-Emtricitabine

    CAS No.:

    143491-57-0

    Molecular Formula:

    C8H10FN3O3S

    InChIKeys:

    InChIKey=XQSPYNMVSIKCOC-NTSWFWBYSA-N

    Molecular Weight:

    247.24700

    Exact Mass:

    247.25

    EC Number:

    604-363-1

    UNII:

    G70B4ETF4S

    DSSTox ID:

    DTXSID0040129

    NCI Thesaurus Code:

    C47509

    Color/Form:

    White to off white powder|White solid from ether and methanol

    ATC Code:

    J05AR03|J05AR06|J05AR|J05AR17|J05AR19|J05|J05AF09|J05AR08|J05AR09|J - Antiinfectives for systemic use

    HScode:

    2934999090

    Characteristics
    PSA:

    115.67000

    XLogP3:

    -0.6

    Density:

    1.82 g/cm3

    Melting Point:

    136-140ºC

    Boiling Point:

    443.3ºC at 760 mmHg

    Flash Point:

    221.9ºC

    Refractive Index:

    1.731

    Water Solubility:

    2.00e+00 g/L

    Storage Conditions:

    Store at 25 deg C (77 deg F); excursions permitted to 15 deg C-30 deg C (59 deg F-86 deg F)

    Vapor Pressure:

    0mmHg at 25°C

    Henrys Law Constant:

    Henry's Law constant = 1.08X10-17 atm-cu m/mole at 25 °C (est)

    Dissociation Constants:

    2.65|pKa = 2.65 (amine)

    Experimental Properties:

    Hydroxy radical reaction rate constant = 1.34X10-10 cu cm/molec-sec at 25 °C (est)|Ozone reaction rate constant = 7.0X10-19 cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

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