Lovastatin Uniform particle size
3 Inquiries
75330-75-5
Pharmaceutical Grade
99%
shenzhen
Flying
10g/1kg/ 10kg/ 25kg
Yes
2026-09-12
vitamin
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceLovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.
Lovastatin is an orally-active hypocholesterolemic useful in the treatment of familial hypercholesterolemia. The drug acts by inhibiting the HMG-CoA reductase-catalyzed rate limiting step of cholesterol biosynthesis. While treatment with lovastatin leads to significant reductions in total and LDL cholesterol, its effect on atherosclerosis or coronary heart disease has not been established.
White Solid
Statins are the most extensively used class of lipid-lowering medication. Lovastatin is the second statin discovered by scientists.Later, the official name lovastatin was established. The activity of lovastatin is much better than compactin.In July 1982, lovastatin showed dramatic effects on lowering LDL cholesterol in patients with severe hypercholesterolemia who were unresponsive to the existedmedicines, with very few adverse reactions .
ChEBI: Lovastatin is a fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom). It has a role as an Aspergillus metabolite, a prodrug, an anticholesteremic drug and an antineoplastic agent. It is a polyketide, a statin (naturally occurring), a member of hexahydronaphthalenes, a delta-lactone and a fatty acid ester. It is functionally related to a (S)-2-methylbutyric acid and a mevastatin.Basic Info-
Product Name:
Lovastatin
Other Name:SiMvastatin EP IMpurity E;Lovastatin,Monacolin K;8-[2-(4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-nap;6alpha-Methylcompactin Mevinolin Monacolin K;)ethyl]-1-naphthalenylester;[1s-[1alpha(r*),3alpha,7beta,8beta(2s*,4s*),8abeta]]-2-methylbutanoicacid1,2,;1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobuty;2-methyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-butanoicaci
CAS No.:75330-75-5
Molecular Formula:C24H36O5
InChIKeys:PCZOHLXUXFIOCF-BXMDZJJMSA-N
Molecular Weight:404.54
Exact Mass:404.54
EC Number:616-212-7
Color/Form:White
HScode:29322090
Categories:
Characteristics-
PSA:
72.8
Physical Properties:Appearance: White, nonhygroscopic crystalline powder. Solubility: Insoluble in water (0.0004mg/mL); sparingly soluble in ethanol, methanol, isobutanol, isopropanol, acetonitrile, n-propanol; soluble in acetone, N-dimethylformamide; freely soluble in chloroform. Melting point: 174.5°C. Specific optical rotation: 25°C for D (sodium) line, +323° (concentration 0.5 g in 100 ml acetonitrile). Stability: Lovastatin is sensitive to light. Following exposure to extreme light conditions, the drug is stable for 24h or 1month when exposed to UV (approximately 3230 lux) or fluorescent (approximately 10,764 lux) light, respectively, at 28°C in air.
XLogP3:4.08
Appearance:Solid
Density:1.12±0.1 g/cm3(Predicted)
Melting Point:175°C
Boiling Point:559.2±50.0 °C(Predicted)
Flash Point:185.3±23.6 °C
Refractive Index:320 ° (C=0.5, CH3CN)
Water Solubility:0.0004 mg/mL at 25 ºC
Storage Conditions:2-8°C
Vapor Pressure:0Pa at 25℃
Toxicity:LD50 orally in mice: >1000 mg/kg (Endo)
Specific rotation:D25 +323° (c = 0.5 g in 100 ml acetonitrile)
PKA:13.49±0.40(Predicted)
Critical Temperature & Pressure:-20°C
Hazard IdentificationClassification of the substance or mixture
Skin sensitization, Category 1
Carcinogenicity, Category 2
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H317 May cause an allergic skin reaction
H351 Suspected of causing cancer
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
vitamin
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Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
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Average lead Time:
25 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Less than 5
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Year of Establishment:
2023
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted
United States
Lovastatin
1 KG Jun 28, 2024
United States
Red yeast rice
1 KG Apr 21, 2026
India
Red Yeast Rice Extract
1.00 MT Jun 29, 2026 Post an enquiry for this product
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