PLX-4720
918505-84-7
98%
Shang Hai
1g/bag-1kg/bag
2026-08-14
SR17018
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferencePLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf.
PLX-4720 is a pyrrolopyridine that is vemurafenib in which the p-chlorophenyl group has been replaced by chlorine. It is a potent and selective inhibitor of the Raf kinase B-Raf(V600E). It has a role as a B-Raf inhibitor and an antineoplastic agent. It is a pyrrolopyridine, a sulfonamide, a difluorobenzene, an organochlorine compound and an aromatic ketone.Basic Info-
Product Name:
N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide
Other Name:1-Propanesulfonamide,N-[3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-;N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide;PLX 4720;1652573-84-6
CAS No.:918505-84-7
Molecular Formula:C17H14ClF2N3O3S
InChIKeys:InChIKey=YZDJQTHVDDOVHR-UHFFFAOYSA-N
Molecular Weight:413.831
Exact Mass:413.83
UNII:EQY31RO8HA
DSSTox ID:DTXSID10238711
Categories:
Characteristics-
PSA:
100
XLogP3:3.3
Density:1.5±0.1 g/cm3
Flash Point:329.6±34.3 °C
Refractive Index:1.646
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
SR17018
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Location:
No. 8 Crown Road, Daguan District, Anqing City
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2017
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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![Calix[4]arene](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/45889cbee0974913b72df67d6c9ad3fc.png "Calix[4]arene")
