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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Mazdutide for Sale > 99% High Purity Mazdutide raw materials GLP-1 Weight Loss Peptides Cas 2259884-03-0 factory selling
99% High Purity Mazdutide raw materials GLP-1 Weight Loss Peptides  Cas 2259884-03-0 factory selling buy - large image1
99% High Purity Mazdutide raw materials GLP-1 Weight Loss Peptides  Cas 2259884-03-0 factory selling buy - image1
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99% High Purity Mazdutide raw materials GLP-1 Weight Loss Peptides  Cas 2259884-03-0 factory selling buy - image6

99% High Purity Mazdutide raw materials GLP-1 Weight Loss Peptides Cas 2259884-03-0 factory selling

5 Inquiries

Unit Price:

$184/UNIT FOB

Get Latest Price
CAS No.:

2259884-03-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

ZQ

Packaging:

10mg*10vials

Price valid (until):

2027-04-09

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Semaglutide

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

                                                                Sales manager:Kate
                                                      WhatsApp:+86 158 3071 9232
                                                          Email:kate@sjzenshi.com


      Product Detail  


    TMazdutide (brand name: Xinelem®) is a global first and the first to be approved for market use, a dual receptor for glucagon (GCG) and glucagon-like peptide-1 (GLP-1), belonging to a long-acting synthetic gastrin-releasing peptide (OXM) analog.
    Core efficacy
       1. Significant weight loss effect
    In overweight/obese adults, a 6 mg dose treatment for 48 weeks resulted in an average weight loss of 14.01%, and some patients achieved a maximum reduction of 21% (high dose 16 mg, in clinical trial stage)
    The proportion of patients with weight loss ≥ 5%: 82.8% in the 6 mg group (vs 11.5% in placebo)
    The average reduction in waist circumference: 10.96 cm (6 mg group)
       2. Improved blood glucose control (applicable to type 2 diabetes)
    After 24 weeks of treatment, glycated hemoglobin (HbA1c) decreased by 2.15% (6 mg group), superior to placebo (-0.14%) and dulaglutide
    In patients with type 2 diabetes combined with obesity, 48% of patients achieved the dual goals of HbA1c < 7.0% and weight loss ≥ 10%, significantly better than semaglutide (21%)
       3. Improved liver fat metabolism
    For patients with baseline liver fat content ≥ 10%, liver fat content decreased by 80.2% after 48 weeks of treatment
    Significantly increased the proportion of liver fat returning to normal (< 5%)
    Multiple metabolic benefits
    Blood pressure: Systolic blood pressure decreased by approximately 6.75 mmHg
    Blood lipids: Triglycerides ↓ 0.52 mmol/L, total cholesterol ↓ 0.45 mmol/L, LDL-C ↓ 0.31 mmol/L

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    Items Specifications
    CAS number 2259884-03-0
    Purity

    99%

    Molecular Weight

    4813.527g/mol

    Appearance

    White powder

    Storage

    Dry and Cool Place, Frozen

    Grade

    Pharmaceutical Grade

    Specification

    5mg 10mg







     Company Profile


    Our company is a modern advanced enterprise specializing in production and exportation of APIs, Pharmaceutical intermediates, plant extracts etc. Our products are widely used in medicine, health care products, cosmetics, nutritional supplements and food additives areas. Our factory covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Since its establishment, the company has attached great importance to the team training and technical reform. Our modern production equipment guarantees for a fast and effective production with a superior degree of accuracy throughout the whole production line, everything is done in-house, processing, extraction, packaging and transportation of all links, ensuring maximum quality and efficiency. We are constantly research and development new ingredients and innovative new products, have earned the respect & Admiration from the worldwide customers. After years of continuous development, company has been accumulated rich experience in international trade and customer resources, established a stable customer base and perfect marketing service network. In addition, the company has established long-term technical cooperation with experts and professors from many universities and research institutes in the province.

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    Since its establishment, the company has attached great importance to the team training and technical reform. Our modern production equipment guarantees for a fast and effective production with a superior degree of accuracy throughout the whole production line, everything is done in-house, processing, extraction, packaging and transportation of all links, ensuring maximum quality and efficiency. We are constantly research and development new ingredients and innovative new products, have earned the respect & Admiration from the worldwide customers. After years of continuous development, company has been accumulated rich experience in international trade and customer resources, established a stable customer base and perfect marketing service network. In addition, the company has established long-term technical cooperation with experts and professors from many universities and research institutes in the province.


    Product Usage  


    Mazdutide (IBI362) is a gastrinoreceptor (OXM) agonist.
    In terms of drug type, it belongs to the peptide class of drugs. This drug activates glucagon-like peptide - 1 receptor (GLP - 1R) and glucagon receptor (GCGR) and has multiple metabolic regulatory effects.
    In terms of therapeutic applications, it is mainly used in the treatment of diseases such as type 2 diabetes and obesity. It reduces body weight by regulating appetite and energy metabolism while improving glycemic control. For example, in clinical trials, Mazdutide demonstrated favorable effects in lowering blood glucose levels and reducing patient weight.

    Acts on the appetite regulation center of the brain to reduce food intake by increasing satiety. Patients will feel fuller more easily and thus spontaneously reduce the amount of food they eat to control calorie intake.

    It can increase energy expenditure. It raises the body's basal metabolic rate, allowing the body to burn more calories even at rest, helping the user to lose weight, a role that is particularly important for obese or overweight patients with type 2 diabetes.
    Some studies have suggested a possible protective effect on the cardiovascular system. This may be through a variety of mechanisms such as improving cardiovascular risk factors such as blood glucose, blood pressure, and lipids, as well as reducing body weight to reduce the risk of cardiovascular disease. However this function needs to be confirmed by more research and clinical trials.

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    FAQ  


    1. How to make an order?
    Send me message and let me know what you need with quantity , then i will calculate to you

    2. What's the lead time and shipping ways?
    We will delivery to the package by USPS, FEDEX, DHL paket and YANWEN express to you after receive your payment, it would take around 5-15 days to your address.

    3. How do i keep the peptides when i receive it ?
    Peptides in the form of lyophilized powder can be transported at room temperature by vacuum packaging, while polypeptides in the dissolved state need to be refrigerated at 2°C - 8°C. For long-term storage, peptides should be stored in the form of lyophilized powder store at -20°C or -80°C in a sealed container with desiccant, which can avoid the degradation of peptides to the greatest extent.

    4. What's the payment methods?
    We could accept pay through paypal,bank transfer, X-Transfer and bitcoin.

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    Pls input...


      Packaging  


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      FQA  


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    Handling and Storage  


    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

    Pls input...

    ECHEMI Editorial Reference

    Mazdutide is a peptide-based GLP-1 and glucagon receptor (GCGR) dual agonist. As a pharmaceutical raw material, Mazdutide is characterized by its dual receptor activity and defined peptide structure. It is suitable for API research, analytical testing, pharmaceutical development, and related manufacturing processes.

    Basic Info
    Product Name:

    Mazdutide

    Other Name:

    Mazdutide;Mazdutide acetate;Mazdutide 10mg;Mazdutide 5mg 10mg;LY-3305677;Mazdutide (IBI-362;OXM-3)

    CAS No.:

    2259884-03-0

    Molecular Weight:

    0

    EC Number:

    884-103-0

    Color/Form:

    White to off-white

    Research
    Class:

    Dual GLP-1R/GCGR agonist (long-acting peptide)

    Status:

    Investigational — Phase 3 (China)

    Mechanism:

    A long-acting dual agonist of the GLP-1 receptor (GLP-1R, Ki = 28.6 nM) and glucagon receptor (GCGR, Ki = 17.7 nM). The dual activation provides both glycemic control (via GLP-1R) and increased energy expenditure / hepatic lipolysis (via GCGR), producing weight loss beyond what GLP-1R agonism alone achieves. Administered once weekly.

    EC50 (GLP1R Ki):

    28.6 nM

    EC50 (GCGR Ki):

    17.7 nM

    Source:

    GlpBio: Mazdutide (CAS 2259884-03-0); Innovent Phase Ib results (eClinicalMedicine 2022).DOI

    Clinical Development:

    NCT04930343; NCT05592656

    References
    PubChem:

    PubChem

    Disclaimer:

    Mazdutide is NOT FDA-approved or EMA-approved. It is in Phase 3 clinical trials in China. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Semaglutide

    Location:

    hangzhou

    Payment Terms:

    TT against copy of documents,D/P,L/C,TT against B/L draft before shipment

    Average lead Time:

    2

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2025

    Our company is a modern advanced enterprise specializing in production and exportation of APIs, Pharmaceutical intermediates, plant extracts etc. Our products are widely used in medicine, health care products, cosmetics, nutritional supplements and food additives areas. Our factory covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Since its establishment, the company has attached great importance to the team training and technical reform. Our modern production equipment guarantees for a fast and effective production with a superior degree of accuracy throughout the whole production line, everything is done in-house, processing, extraction, packaging and transportation of all links, ensuring maximum quality and efficiency. We are constantly research and development new ingredients and innovative new products, have earned the respect & Admiration from the worldwide customers. After years of continuous development, company has been accumulated rich experience in international trade and customer resources, established a stable customer base and perfect marketing service network. In addition, the company has established long-term technical cooperation with experts and professors from many universities and research institutes in the province.

  • Inquiry History
    5 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Mazdutide

    30 MG Jul 15, 2024
    United States

    Mazdutide

    25 MG Aug 12, 2026
    Nigeria

    Mazdutide 10mg

    20 PCS Mar 7, 2026
    United Kingdom

    Mazdutide

    1 KG Feb 10, 2026
    United States

    Mazddultide cas

    2 MT Nov 14, 2025
    Post an enquiry for this product
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