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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Pemetrexed disodium hemipenta hydrate for Sale > Pemetrexed Disodium Hemipentahydrate CAS 357166-30-4 Antifolate API for NSCLC and Mesothelioma hfd
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Pemetrexed Disodium Hemipentahydrate CAS 357166-30-4 Antifolate API for NSCLC and Mesothelioma hfd

TDS

Unit Price:

$100-130/G FOB

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CAS No.:

357166-30-4

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

5g, 25g, 100g, 500g

Price valid (until):

2026-09-17

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Description

    —— Product Specification ——

    Parameter Specification Details
    Product Name Pemetrexed Disodium Hemipentahydrate Pemetrexed disodium salt 2.5 hydrate
    CAS Number 357166-30-4 357166-30-4
    Molecular Formula C₂₀H₁₉N₅Na₂O₆·2.5H₂O Equivalent to 2(C₂₀H₁₉N₅Na₂O₆)·5H₂O
    Molecular Weight 516.43 g/mol (anhydrous)
    Appearance White to off-white powder Visual inspection
    Purity ≥98.0% Determined by HPLC
    Ki (TS) 1.3 nM Thymidylate synthase inhibition
    Ki (DHFR) 7.2 nM Dihydrofolate reductase inhibition
    Ki (GARFT) 65 nM Glycinamide ribonucleotide formyltransferase inhibition
    Storage -20°C for long-term; 2-8°C for short-term Sealed containers, protect from light and moisture
    Packaging 10mg, 25mg, 50mg, 100mg, 1g Amber glass vials
    Application Research use only Antifolate research, antimetabolite studies, reference standard


    —— Product Detail ——

    Product Overview

    • Pemetrexed Disodium Hemipentahydrate (CAS 357166-30-4) is the hydrated disodium salt form of pemetrexed, a novel antifolate and multitargeted antimetabolite with a pyrrolo[2,3-d]pyrimidine core structure. It appears as a white to off-white powder with the molecular formula C₂₀H₁₉N₅Na₂O₆·2.5H₂O and a molecular weight of 516.43 g/mol. The compound is also known by the brand name Alimta.


    Packaging & Shipping

                  • Research quantities: 5mg, 10mg, 25mg amber glass vials

                  • Bulk quantities: 50mg, 100mg amber glass bottles

                  • Custom packaging available upon request

                  • Not classified as hazardous material for transport under normal conditions

                  • Product for research and analytical use only; not for human therapeutic use

    Shop CAS 18048-64-1 Eltrombopag Intermediate for Pharmaceutical Research  kr-Detailed Image 1

    Company profile ——


     Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 1

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

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    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    ECHEMI Editorial Reference
    Pemetrexed disodium hemipenta hydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.

    Certificates
    • Pemetrexed Disodium Hemipentahydrate CAS 357166-30-4 Antifolate API for NSCLC and Mesothelioma hfd Certificates 1 TDS

    Basic Info
    Product Name:

    Pemetrexed disodium hemipenta hydrate

    CAS No.:

    357166-30-4

    Molecular Formula:

    2(C20H19N5Na2O6).5(H2O)

    InChIKeys:

    ZCTCZKWJFTYNMZ-WKUCUCPSSA-J

    Molecular Weight:

    1032.84

    Exact Mass:

    1032.278967 g/mol

    EC Number:

    1806241-263-5

    Characteristics
    PSA:

    439.99000

    XLogP3:

    -2.38330

    Hazard Identification

    Classification of the substance or mixture

    Germ cell mutagenicity, Category 2

    Reproductive toxicity, Category 1B

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H341 Suspected of causing genetic defects

    H360 May damage fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Country Product Purchase Quantity Date Posted
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