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Pemetrexed disodium hemipenta hydrate

Pemetrexed disodium hemipenta hydrate structure

CAS No:
357166-30-4
Formula:
2(C20H19N5Na2O6).5(H2O)
Chemical Name:
Pemetrexed disodium hemipenta hydrate
Categories:
Biochemical Engineering > Amino Acids and Derivatives

Description

Pemetrexed disodium hemipenta hydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.

Pemetrexed disodium hemipenta hydrate Basic Attributes

Molecular Weight：

1032.84

Exact Mass：

1032.278967 g/mol

EC Number：

1806241-263-5

Characteristics

PSA：

439.99000

XLogP3：

-2.38330

Pemetrexed disodium hemipenta hydrate Use and Manufacturing

Pemetrexed Disodium Hydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Hydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.

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Pemetrexed Disodium Hemipentahydrate CAS 357166-30-4 Antifolate API for NSCLC and Mesothelioma hfd

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What is Palmitoyl Tripeptide -5

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What is Acetyl Tetrapeptide-5

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Guide of Pemetrexed disodium hemipenta hydrate

Description
Basic Attributes
Characteristics
Use and Manufacturing
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