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Home > Encyclopedia > Pemetrexed disodium hemipenta hydrate

Pemetrexed disodium hemipenta hydrate

pharmaceutical raw materials
Pemetrexed disodium hemipenta hydrate structure

Pemetrexed disodium hemipenta hydrate 

structure

Description

Pemetrexed disodium hemipenta hydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.

Pemetrexed disodium hemipenta hydrate Basic Attributes

1032.84

1032.278967 g/mol

1806241-263-5

Characteristics

439.99000

-2.38330

Pemetrexed disodium hemipenta hydrate Use and Manufacturing

Pemetrexed Disodium Hydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Hydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.

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