Pemetrexed disodium hemipenta hydrate
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Pemetrexed disodium hemipenta hydrate
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CAS No:
357166-30-4
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Formula:
2(C20H19N5Na2O6).5(H2O)
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Chemical Name:
Pemetrexed disodium hemipenta hydrate
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CAS No:
Description
Pemetrexed disodium hemipenta hydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
Pemetrexed disodium hemipenta hydrate Use and Manufacturing
Pemetrexed Disodium Hydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Hydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.
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Pemetrexed disodium hemipenta hydrate
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