—— Product Specifications ——

—— Product Detail ——

Product Overview

4-Aminobenzoic acid (PABA, CAS 150-13-0) is an aromatic amino acid derivative with the molecular formula C₇H₇NO₂ and a molecular weight of 137.14 g/mol. It appears as a white to pale yellow crystalline powder that turns light yellow upon exposure to air and light. PABA is a component of folate (vitamin B9) and is widely distributed in nature, found in yeast, liver, bran, and malt. It is soluble in hot water, alcohol, ether, ethyl acetate, and glacial acetic acid, with a solubility of 4.7 g/L in water at 20°C and 121 g/L in ethanol. This compound is a key intermediate in the synthesis of local anesthetics (such as benzocaine and procaine), folic acid, and azo dyes. It is also used as a reagent for copper determination and in laboratory applications as a sulfonamide antagonist.

Synthetic Process

The synthesis of 4-aminobenzoic acid typically involves the reduction of 4-nitrobenzoic acid, followed by purification through recrystallization. It can also be produced through the Kolbe-Schmitt reaction or other synthetic routes from benzoic acid derivatives. Industrial production often employs catalytic hydrogenation of the nitro precursor.

Mechanism of Action

PABA functions as a growth factor for certain microorganisms and is a structural component of folic acid (pteroylglutamic acid). In biological systems, it acts as a competitive inhibitor of sulfonamide antibiotics, which are structural analogs of PABA. As a research reagent, it is used in studies of folate metabolism and as a precursor for various pharmaceutical compounds.

Quality Specifications

• Purity: ≥99.0% determined by HPLC and titration

• Identity confirmed by NMR and mass spectrometry

• Melting point: 186-189°C

• Loss on drying: ≤0.2%

• Residue on ignition: ≤0.1%

• Heavy metals: ≤0.002%

• Each batch accompanied by comprehensive Certificate of Analysis (COA)

• Store in a cool, dry place, protected from light (store under inert gas recommended)

Packaging & Shipping

• Research quantities: 25g, 100g amber glass vials

• Bulk quantities: 500g, 1kg amber glass bottles

• Custom packaging available upon request

• Shipped at ambient temperature for routine orders

— C ompany Profile ——

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

—— Q&A ——

Q1: How to confirm the product quality before placing orders?
A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

Q2: Can you supply free samples?
A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

Q3: How do you treat quality complaints?
A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

Q4: What is your MOQ? Is there a discount?
A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantities, we always support with better prices.

Q5: How to start orders or make payments?
A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.