Fluconazole CAS 86386-73-4 Triazole Antifungal Agent for Candidiasis and Cryptococcosis hfd
TDS 16 Inquiries
86386-73-4
Reagent Grade
99%
qingdao
//
5g, 25g, 100g, 500g
2026-09-19
Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceFluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.Target: AntifungalFluconazole is a triazole antifungal intended for oral treatment of superficial and systemic mycoses. In tests done in standard mycological media, the compound had minimal inhibitory concentrations against pathogenic Candida species that were usually in excess of 100 mg/l. Fluconazole inhibited branching and hyphal development in C. albicans at co
Solid
Fluconazole is a member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis. It has a role as a P450 inhibitor, an environmental contaminant and a xenobiotic. It is a difluorobenzene, a conazole antifungal drug, a triazole antifungal drug and a tertiary alcohol. It derives from a 1,3-difluorobenzene. It derives from a hydride of a 1H-1,2,4-triazole.|Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as [ketoconazole] and [itraconazole]. Fluconazole has many advantages over the other antifungal drugs including the option of oral administration. The side effect profile of this drug is minimal. It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose.|Fluconazole is an Azole Antifungal. The mechanism of action of fluconazole is as a Cytochrome P450 2C19 Inhibitor, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inhibitor.|Fluconazole is a triazole fungistatic agent used in the treatment of systemic and superficial fungal infections. Fluconazole therapy can cause transient mild-to-moderate serum aminotransferase elevations and is a known cause of clinically apparent acute drug induced liver injury.|Fluconazole is a synthetic triazole with antifungal activity. Fluconazole preferentially inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols, the loss of normal fungal sterols, and fungistatic activity. Mammalian cell demethylation is much less sensitive to fluconazole inhibition.|Triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.Certificates-
TDS
Basic Info-
Product Name:
Fluconazole
Other Name:1H-1,2,4-Triazole-1-ethanol,α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-;α-(2,4-Difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol;UK 49858;Fluconazole;Diflucan;Flucostat;Biozolene;Elazor;Triflucan;Flusol;Zoltec;Flunazol;Flumycon;Fluzon;Difluconazole;Fluconal;1-(2,4-Difluorophenyl)-1,1-bis[(1H-1,2,4-triazol-1-yl)methyl]methanol;Triconal;Zocon;Flucan;Fungicon;Fungican;Alkanazole;Flutec;2-(2,4-Difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)-propan-2-ol;Floroxan;2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol;123631-92-5
CAS No.:86386-73-4
Molecular Formula:C13H12F2N6O
InChIKeys:InChIKey=RFHAOTPXVQNOHP-UHFFFAOYSA-N
Molecular Weight:306.27100
Exact Mass:306.27
UNII:8VZV102JFY
NSC Number:758661
DSSTox ID:DTXSID3020627
NCI Thesaurus Code:C500
Color/Form:White crystalline powder|Crystals from ethyl acetate/hexane
ATC Code:J02AC01|D - Dermatologicals|J - Antiinfectives for systemic use
HScode:2933990090
Categories:
Characteristics-
PSA:
81.65000
XLogP3:0.4
Appearance:Solid
Density:1.49 g/cm3
Melting Point:138-140 °C
Boiling Point:579.8ºC at 760 mmHg
Flash Point:304.4ºC
Refractive Index:1.663
Water Solubility:1g/L(temperature not stated)
Storage Conditions:-20ºC
Vapor Pressure:3.0X10-9 mm Hg at 25 deg C (est)
PKA:1.76None
Henrys Law Constant:Henry's Law constant = 1.0X10-13 atm-cu m/mole at 25 °C (est)
Dissociation Constants:1.76|pKa = 2.27 (1,2,4-triazole)
Collision Cross Section:163.9 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]|163.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Hydroxyl radical reaction rate constant = 11.1X10-12 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Reproductive toxicity, Category 1B
Specific target organ toxicity â single exposure, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H360 May damage fertility or the unborn child
H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P318 IF exposed or concerned, get medical advice.
P308+P316 IF exposed or concerned: Get emergency medical help immediately.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524
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Location:
RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2022
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Inquiry History16 Inquiries
Country Product Purchase Quantity Date Posted
India
Fluconazole 99% Best Price 86386-73-4 99% powder
1000 MT Sep 1, 2023
United States
Fluconazole (Diflucan) powder CAS 86386-73-4 Fluconazole for Anti-Bacterium
3 KG May 11, 2024
United States
China Most Professional Factory Supply High Qulity Fluconazole CAS 86386-73-4
5 KG Jun 16, 2026
Bangladesh
Fluconazole
1000.00 KG Dec 11, 2025
United States
Fluconazole 99% white powder
100 G Dec 14, 2023
Bangladesh
Fluconazole API USP
1000 KG Aug 20, 2026
India
Fluconazole.
500.00 KG May 8, 2025
Denmark
Fluconazole
1 KG Feb 22, 2024
United States
Fluconazole
2500 MG Sep 18, 2025
United States
Fluconazole
5 MT Aug 30, 2025
Pakistan
FLUCONAZOLE
75 KG Aug 25, 2025
Pakistan
FLUCONAZOLE
20 KG May 23, 2025
India
Fluconazole
500.00 KG Dec 25, 2024
United States
Flucanazole
25 G Jun 28, 2024
Tunisia
fluconazole
5 KG Dec 19, 2023
United States
Fluconozole 86386-73-4
30 G Dec 18, 2023 Post an enquiry for this product
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