Amphotericin B raw powder CAS 1397-89-3 High Purity 99%
1397-89-3
Pharmaceutical Grade
99%
shenzhen
None
1kg/bag 25kg/drum
2026-09-21
API
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceAmphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
Amphotericin B is an antifungal agent with a broad spectrum of activity against many fungal species. Amphotericin B commonly causes mild to moderate serum aminotransferase elevations and can cause hyperbilirubinemia, but acute, clinically apparent drug induced liver injury from amphotericin B therapy is exceedingly rare.Basic Info-
Product Name:
Fungizone
Other Name:Amphotericin B;Fungizone;14,39-Dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid,33-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-,(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-;Fungilin;Ampho-Moronal;(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-Amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid;AmBisome;NS 718;Abelcet;LNS-AmB;Halizon;Amphozone;Amphocin;NSC 527017;Apothecon;Fungizona;Abelecet;Kalsome 10;1407-52-9;8055-20-7;30782-62-8;54482-28-9;170451-78-2;1802392-71-7
CAS No.:1397-89-3
Molecular Formula:C47H73NO17
InChIKeys:InChIKey=APKFDSVGJQXUKY-INPOYWNPSA-N
Molecular Weight:924.08
Exact Mass:924.08
EC Number:215-742-2
DSSTox ID:DTXSID9022601
Color/Form:Deep yellow prisms or needles from n,n-dimethylformamide|YELLOW TO ORANGE POWDER
ATC Code:A - Alimentary tract and metabolism|G - Genito urinary system and sex hormones|J - Antiinfectives for systemic use
Categories:
Characteristics-
PSA:
320
XLogP3:log Kow = -2.80 (est)
Appearance:yellow powder
Density:1.3±0.1 g/cm3
Melting Point:>170 °C (decomp)
Boiling Point:1140.365°C at 760 mmHg
Flash Point:643.5±34.3 °C
Refractive Index:1.614
Water Solubility:H2O: <0.1 g/100 mL at 21 ºC;sterile water: 20 mg/mL as a stock solution.
Storage Conditions:2-8°C
Vapor Pressure:0mmHg at 25°C
Toxicity:Intravenous-rat LD50: 11.3 mg/kg; peritoneal-mouse LD50: 27.74 mg/kg
Flammability characteristics:Flammable; heat produces toxic nitrogen oxide fumes
Specific rotation:D24 +333° (acidic DMF); -33.6° (0.1N methanolic HCl)
Odor:ODORLESS OR PRACTICALLY SO
Experimental Properties:Hydroxyl radical reaction rate constant = 6.5X10-10 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Conventional amphotericin B powder for injection should be stored at 2-8 deg C. Reconstituted colloidal dispersions of conventional amphotericin B should be protected from light and are stable for 24 hours at room temperature or 1 week when refrigerated at 2-8 deg C. Although the manufacturers state that reconstituted dispersions or IV infusions of amphotericin B should be protected from light during administration, potency is unaffected if the infusion is exposed to light for less than 8-24 hours.
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Seller Information
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Business Type:
Trader
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Main Products:
API
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Location:
1806 Building B,Science Building,Hongkong Road,Wuhan City,Hubei Province
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Year of Establishment:
2024
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
