Anwuligan 98% Purity Natural Product Reference Standard Lignan Compound High-Purity Research Material CAS 107534-93-0 for Phytochemical and Pharmacolo

Product Overview

Anwuligan is a naturally occurring lignan compound isolated from the roots and rhizomes of certain medicinal plants, most notably from species of the genus Angelica and Peucedanum within the Apiaceae family. Chemically, it is a tetrahydrofuran-type lignan with the molecular formula C₂₀H₂₂O₆ and a molecular weight of approximately 358.4 g/mol. The compound features a dibenzylbutyrolactone skeleton with multiple oxygenated substituents, including methoxy and hydroxy groups, which contribute to its biological activity.

Anwuligan has been identified as a bioactive constituent in traditional Chinese medicinal herbs, where it is considered one of the marker compounds for quality control and standardization of botanical extracts. As a high-purity reference standard, it is widely used in phytochemical analysis, pharmacological research, and the development of natural product-based therapeutics.

Natural Sources and Biosynthesis

Anwuligan is biosynthesized through the phenylpropanoid pathway, where two coniferyl alcohol units undergo oxidative coupling to form the lignan skeleton. Subsequent enzymatic modifications, including cyclization, hydroxylation, and methylation, yield the final compound. The lignan is predominantly found in the roots of Angelica species, where it may serve as a defense compound against pathogens and herbivores, as well as a signaling molecule in plant stress responses.

The compound has been isolated from various plant sources, including:

• Angelica sinensis (Dong Quai/Danggui)

• Angelica acutiloba (Japanese Angelica root)

• Peucedanum praeruptorum (Baihua Qianhu)

• Forsythia suspensa (Lianqiao)

Biological Activities and Research Applications

Anwuligan exhibits a diverse range of biological activities that make it a compound of significant research interest:

• Anti-inflammatory Activity: Demonstrates inhibition of pro-inflammatory mediators, including COX-2, iNOS, and TNF-α, through modulation of NF-κB signaling pathways

• Hepatoprotective Effects: Shows protective activity against chemically induced liver damage, potentially through antioxidant and anti-inflammatory mechanisms

• Antioxidant Properties: Exhibits free radical scavenging activity, protecting cells against oxidative stress-induced damage

• Neuroprotective Potential: Preliminary studies suggest protective effects against neuronal cell death, possibly through inhibition of oxidative stress and apoptotic pathways

• Antimicrobial Activity: Demonstrates moderate activity against certain bacterial and fungal strains

• Cardiovascular Effects: May contribute to vascular relaxation and blood pressure regulation through mechanisms involving nitric oxide pathways

Quality Specifications

Our Anwuligan is manufactured under rigorous quality control standards:

• Purity: ≥98.0% determined by HPLC area normalization

• Identity confirmed by NMR (¹H, ¹³C) and high-resolution mass spectrometry

• Water content: ≤1.0% (Karl Fischer)

• Residual solvents: Meet ICH Q3C guidelines

• Each batch supplied with comprehensive Certificate of Analysis (COA)

• Stable for 24 months when stored at 2-8°C in sealed, light-protected containers

Packaging & Shipping

We offer flexible packaging options for research requirements:

• Research quantities: 20mg, 50mg, 100mg amber glass vials

• Custom packaging available upon request

• Shipped at ambient temperature with desiccant

• International shipping with full documentation available

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.