Angelol A 98% Purity Research Grade Coumarin Compound CAS 19625-17-3 for Natural Product Reference Standard

• Product Overview

  Angelol A is a naturally occurring coumarin compound isolated from Angelica pubescens and other Angelica species. It belongs to the class of pyranocoumarins and is one of the characteristic bioactive components of Angelica plants. Angelol A has been studied for its pharmacological properties including anti-inflammatory, analgesic, and vasodilatory activities.

  Chemically, angelol A is a coumarin derivative with the molecular formula C₂₀H₂₄O₆ and a molecular weight of 360.40 g/mol. It appears as a white to off-white crystalline powder, soluble in methanol, ethanol, and chloroform. The compound is supplied at ≥98% purity as determined by HPLC analysis.

  Synthetic Process:

  This compound is obtained through isolation from natural plant sources:

  Extraction: Angelica pubescens root or other Angelica species is extracted with methanol or ethanol. The extract is concentrated and subjected to liquid-liquid partitioning.

  Purification: The coumarin-enriched fraction is purified by silica gel column chromatography using petroleum ether-ethyl acetate gradient elution, followed by recrystallization to obtain pure angelol A.

  This product is a high-purity analytical reference standard intended for natural product research.

  Research Applications

  • Natural Product Chemistry: Used as a reference compound for coumarin analysis in Angelica species

  • Pharmacological Research: Evaluated for anti-inflammatory, analgesic, and vasodilatory activities

  • Quality Control: Serves as a marker compound for Angelica pubescens standardization

  Quality Specifications

  • Purity: ≥98.0% determined by HPLC

  • Identity confirmed by NMR and MS

  • Each batch accompanied by Certificate of Analysis

  • Stable for 36 months when stored at 2-8°C in sealed, light-protected containers

  Packaging & Shipping

  • Standard packaging: 5mg amber glass vials

  • Custom packaging available upon request

  • Shipped at ambient temperature

  • International shipping available

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.