China Origin ISO9001 Factory Direct Supply KissPeptin-10 5mg/10mg Lyophilized Powder for Export,

  Product Detail  

Product Name: Kisspeptin-10 (mouse, rat)

CAS Number: 478507-53-8

Molecular Formula: C63H83N17O15

Molecular Weight: 1318.44

Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2

Kisspeptin-10 (mouse, rat) is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10 (mouse, rat) is a ligand for the kissin receptor GPR54 (also known as KISS1). Kisspeptin-10 reduces methotrexate-induced reproductive toxicity and has potential antioxidant activity.

♔ Applications and Effects:

① Reproductive Regulation: Kisspeptin-10 plays a crucial role in reproductive biology and is a key regulator of the hypothalamic-pituitary-gonadal axis. It primarily regulates gonadal function and the reproductive cycle by binding to the kissin receptor GPR54 (also known as KISS1), influencing the secretion of gonadotropin-releasing hormone (GnRH). In rodent models, kisspeptin-10 plays a crucial role in the onset of puberty and the maintenance of reproductive function.

② Vasoconstriction and Angiogenesis: Kisspeptin-10 not only plays a role in the reproductive system but also has potential effects on the cardiovascular system. Studies have shown that kisspeptin-10 can increase cardiac contractility and induce fibrosis and changes in mitochondrial structure in rat heart tissue. These changes suggest that kisspeptin-10 may play a key role in the pathogenesis of heart disease.

③ Antioxidant Activity: Studies have shown that kisspeptin-10 also has potential antioxidant activity, potentially reducing the reproductive toxicity induced by certain drugs, such as methotrexate, this makes kisspeptin-10 a potential therapeutic peptide that can be used to improve sexual desire, muscle growth, and other aspects.